ENSDARG00000103394


Danio rerio

Features
Gene ID: ENSDARG00000103394
  
Biological name :kif5bb
  
Synonyms : kif5ba / kif5bb / kinesin family member 5B, b
  
Possible biological names infered from orthology : KIF5B / Kinesin-1 heavy chain / kinesin family member 5B / P33176 / Q61768
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 41510492
Gene end: 41551599
  
Corresponding Affymetrix probe sets: Dr.11327.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000144042
Ensembl peptide - ENSDARP00000138324
NCBI entrez gene - 334108     See in Manteia.
swissprot - F1R5M2
swissprot - A0A0R4IRM1
ZFIN ID - ZDB-GENE-070629-4
ZFIN ID - ZDB-GENE-070629-2
Ensembl - ENSDARG00000103394
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KIF5BENSGALG00000007215Gallus gallus
 KIF5BENSG00000170759Homo sapiens
 Kif5bENSMUSG00000006740Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kif5ba / kinesin family member 5B, a / KIF5B* / Q61768* / P33176* / Kinesin-1 heavy chain * / kinesin family member 5B*ENSDARG0000007413191
kif5c / kinesin family member 5C / O60282* / P28738* / Kinesin heavy chain isoform 5C *ENSDARG0000007602770
kif5aa / kinesin family member 5A, a / KIF5A* / Q12840* / kinesin family member 5A*ENSDARG0000009893666
kif5ab / kinesin family member 5A, b / KIF5A* / P33175* / Q12840* / kinesin family member 5A* / Kinesin heavy chain isoform 5A *ENSDARG0000005981864
kif21a / kinesin family member 21A / Q7Z4S6* / Q9QXL2* / Kinesin-like protein KIF21A *ENSDARG0000006113126
kif7 / kinesin family member 7 / Q2M1P5*ENSDARG0000003309925
kif21b / kinesin family member 21B / O75037*ENSDARG0000000973325
kif4 / kinesin family member 4 / KIF4A* / KIF4B* / Q2VIQ3* / O95239* / P33174* / kinesin family member 4A* / kinesin family member 4B* / Chromosome-associated kinesin KIF4 *ENSDARG0000000546223
kif11 / kinesin family member 11 / P52732* / Q6P9P6* / Kinesin-like protein KIF11 *ENSDARG0000001094823
kif15 / kinesin family member 15 / Q6P9L6* / Q9NS87* / Kinesin-like protein KIF15 *ENSDARG0000001207323
cenpe / centromere protein E / Q02224*ENSDARG0000006338522
kif17 / kinesin family member 17 / Q99PW8* / Q9P2E2* / Kinesin-like protein KIF17 *ENSDARG0000005523822
kif3b / kinesin family member 3B / O15066* / Q61771* / Kinesin-like protein KIF3B Kinesin-like protein KIF3B, N-terminally processed*ENSDARG0000010112021
kif3ca / kinesin family member 3Ca / KIF3C* / O14782* / kinesin family member 3C*ENSDARG0000001716221
kif3a / kinesin family member 3A / P28741* / Q9Y496* / Kinesin-like protein KIF3A *ENSDARG0000008753820
kif3cb / kinesin family member 3Cb / KIF3C* / O14782* / O35066* / kinesin family member 3C* / Kinesin-like protein KIF3C *ENSDARG0000007950020
CABZ01066312.1ENSDARG000001006243


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007281 germ cell development IMP
 biological_processGO:0007411 axon guidance IBA
 biological_processGO:0007519 skeletal muscle tissue development IGI
 biological_processGO:0008104 protein localization IBA
 biological_processGO:0030705 cytoskeleton-dependent intracellular transport IBA
 biological_processGO:0051216 cartilage development IGI
 biological_processGO:0060349 bone morphogenesis IGI
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA


Pathways (from Reactome)
Pathway description
RHO GTPases activate KTN1
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
Show

 ZFA:0000093 blastomere blastomere cleavage furrow absent , abnormal
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 ZFA:0000155 somite somite cuboid , abnormal
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 ZFA:0000191 dentary dentary decreased size , abnormal
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 ZFA:0000476 branchiostegal ray branchiostegal ray decreased size , abnormal
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 ZFA:0000511 extraocular musculature extraocular musculature M band morphology , abnormal
Show

 ZFA:0000598 testis testis lacks all parts of type germ line cell , abnormal
Show

 ZFA:0000657 entopterygoid entopterygoid decreased size , abnormal
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 ZFA:0001058 caudal fin caudal fin skeletal muscle cell broken , abnormal
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 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
whole organism lacks all parts of type notochord , abnormal
whole organism lacks all parts of type primordial germ cell , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head flattened , abnormal
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 ZFA:0001115 trunk trunk skeletal muscle cell broken , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage curved , abnormal
Meckels cartilage shortened , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton chondrocyte position , abnormal
mandibular arch skeleton protruding , abnormal
mandibular arch skeleton chondrocyte morphology , abnormal
mandibular arch skeleton protruding , exacerbated
mandibular arch skeleton decreased size , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage shortened , abnormal
palatoquadrate cartilage chondrocyte position , abnormal
palatoquadrate cartilage chondrocyte circular , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage curved , abnormal
ceratohyal cartilage shortened , abnormal
ceratohyal cartilage increased angle to ceratohyal cartilage , abnormal
ceratohyal cartilage apoptotic process increased occurrence , abnormal
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 ZFA:0001570 unfertilized egg unfertilized egg increased amount , abnormal
unfertilized egg posterior region increased amount , abnormal
unfertilized egg posterior region increased distribution , abnormal
unfertilized egg posterior region has extra parts of type unfertilized egg cortical granule, abnormal
unfertilized egg microtubule disorganized , abnormal
unfertilized egg posterior region mislocalised , abnormal
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 ZFA:0001591 endochondral bone endochondral bone bone mineralization decreased occurrence , abnormal
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 ZFA:0001630 perichondral bone perichondral bone autophagy occurrence , abnormal
perichondral bone bone mineralization decreased occurrence , abnormal
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 ZFA:0001634 perichondrium perichondrium disorganized , abnormal
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 ZFA:0009084 chondrocyte chondrocyte mitochondrion position , abnormal
chondrocyte endoplasmic reticulum position , abnormal
chondrocyte extracellular matrix spatial pattern , abnormal
chondrocyte secretion decreased occurrence , abnormal
chondrocyte increased amount , abnormal
chondrocyte degenerate , abnormal
chondrocyte vacuole increased amount , abnormal
chondrocyte rough endoplasmic reticulum distended , abnormal
chondrocyte decreased amount , abnormal
chondrocyte lysosome increased size , abnormal
chondrocyte apoptotic process increased occurrence , abnormal
chondrocyte centrosome position , abnormal
chondrocyte centrosome polarity , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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