ENSDARG00000034268


Danio rerio

Features
Gene ID: ENSDARG00000034268
  
Biological name :slit3
  
Synonyms : slit3 / slit homolog 3 (Drosophila)
  
Possible biological names infered from orthology : O75094 / Q9WVB4 / slit guidance ligand 3 / Slit homolog 3 protein
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 24491818
Gene end: 24761161
  
Corresponding Affymetrix probe sets: Dr.10716.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000112770
NCBI entrez gene - 80354     See in Manteia.
RefSeq - NM_131736
RefSeq Peptide - NP_571811
swissprot - F1RCV3
ZFIN ID - ZDB-GENE-010306-4
Ensembl - ENSDARG00000034268
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLIT3ENSGALG00000001916Gallus gallus
 SLIT3ENSG00000184347Homo sapiens
 Slit3ENSMUSG00000056427Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slit2 / slit homolog 2 (Drosophila) / O94813* / Q9R1B9* / slit guidance ligand 2*ENSDARG0000000424662
slit1a / slit homolog 1a (Drosophila) / SLIT1* / Q80TR4* / O75093* / slit guidance ligand 1* / Slit homolog 1 protein *ENSDARG0000004495456
slit1b / slit homolog 1b (Drosophila) / SLIT1* / Q80TR4* / O75093* / slit guidance ligand 1* / Slit homolog 1 protein *ENSDARG0000009944655
crb1 / crumbs family member 1, photoreceptor morphogenesis associated / 1 * / P82279* / Q8VHS2* / crumbs 1, cell polarity complex component*ENSDARG0000010050615
crb2a / crumbs family member 2a / 2 * / CRB2* / Q5IJ48* / Q80YA8* / crumbs 2, cell polarity complex component*ENSDARG0000006010615
dner / delta/notch-like EGF repeat containing / Q8NFT8*ENSDARG000000610319
crb2b / crumbs family member 2b / CRB2* / Q5IJ48* / crumbs 2, cell polarity complex component*ENSDARG000000600819
dlk2 / delta-like 2 homolog (Drosophila) / 2 * / Q6UY11* / Q8K1E3* / delta like non-canonical Notch ligand 2*ENSDARG000000762476
CR456624.1 / DLL3* / O88516* / Q9NYJ7* / Delta-like protein 3 * / delta like canonical Notch ligand 3*ENSDARG000000795194
CABZ01102109.1 / DLK1* / P80370* / delta like non-canonical Notch ligand 1*ENSDARG000001142263


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR000742  EGF-like domain
 IPR001611  Leucine-rich repeat
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR003591  Leucine-rich repeat, typical subtype
 IPR006207  Cystine knot, C-terminal
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018097  EGF-like calcium-binding, conserved site
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0021952 central nervous system projection neuron axonogenesis IMP
 biological_processGO:0030517 negative regulation of axon extension IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Signaling by ROBO receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001657 supraoptic tract supraoptic tract axon extension process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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