ENSDARG00000076247


Danio rerio

Features
Gene ID: ENSDARG00000076247
  
Biological name :dlk2
  
Synonyms : delta-like 2 homolog (Drosophila) / dlk2
  
Possible biological names infered from orthology : 2 / delta like non-canonical Notch ligand 2 / Q6UY11 / Q8K1E3
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 4205724
Gene end: 4213909
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000118418
swissprot - F1QL03
ZFIN ID - ZDB-GENE-081107-4
Ensembl - ENSDARG00000076247
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DLK2ENSGALG00000010386Gallus gallus
 DLK2ENSG00000171462Homo sapiens
 2 ENSMUSG00000047428Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
crb2a / crumbs family member 2a / 2 * / CRB2* / Q5IJ48* / Q80YA8* / crumbs 2, cell polarity complex component*ENSDARG0000006010628
slit3 / slit homolog 3 (Drosophila) / Q9WVB4* / O75094* / slit guidance ligand 3* / Slit homolog 3 protein *ENSDARG0000003426826
slit2 / slit homolog 2 (Drosophila) / O94813* / Q9R1B9* / slit guidance ligand 2*ENSDARG0000000424625
crb1 / crumbs family member 1, photoreceptor morphogenesis associated / 1 * / P82279* / Q8VHS2* / crumbs 1, cell polarity complex component*ENSDARG0000010050625
slit1a / slit homolog 1a (Drosophila) / SLIT1* / Q80TR4* / O75093* / slit guidance ligand 1* / Slit homolog 1 protein *ENSDARG0000004495424
slit1b / slit homolog 1b (Drosophila) / SLIT1* / Q80TR4* / O75093* / slit guidance ligand 1* / Slit homolog 1 protein *ENSDARG0000009944624
dner / delta/notch-like EGF repeat containing / Q8NFT8*ENSDARG0000006103123
CABZ01102109.1 / DLK1* / P80370* / delta like non-canonical Notch ligand 1*ENSDARG0000011422622
crb2b / crumbs family member 2b / CRB2* / Q5IJ48* / crumbs 2, cell polarity complex component*ENSDARG0000006008116
CR456624.1 / DLL3* / O88516* / Q9NYJ7* / Delta-like protein 3 * / delta like canonical Notch ligand 3*ENSDARG000000795197


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0045746 negative regulation of Notch signaling pathway IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005035 subintestinal vein subintestinal vein sprouting angiogenesis increased occurrence , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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