ENSG00000171462


Homo sapiens

Features
Gene ID: ENSG00000171462
  
Biological name :DLK2
  
Synonyms : delta like non-canonical Notch ligand 2 / DLK2 / Q6UY11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.1
Gene start: 43450352
Gene end: 43456632
  
Corresponding Affymetrix probe sets: 220262_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000399829
Ensembl peptide - ENSP00000349893
Ensembl peptide - ENSP00000361563
Ensembl peptide - ENSP00000361566
NCBI entrez gene - 65989     See in Manteia.
RefSeq - XM_017011204
RefSeq - NM_001286655
RefSeq - NM_001286656
RefSeq - NM_023932
RefSeq - NM_206539
RefSeq - XM_005249308
RefSeq - XM_011514823
RefSeq Peptide - NP_001273585
RefSeq Peptide - NP_076421
RefSeq Peptide - NP_996262
RefSeq Peptide - NP_001273584
swissprot - Q5T3T9
swissprot - Q6UY11
swissprot - H0Y5P1
swissprot - A0A024RD55
Ensembl - ENSG00000171462
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dlk2ENSDARG00000076247Danio rerio
 DLK2ENSGALG00000010386Gallus gallus
 2 ENSMUSG00000047428Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DLK1 / P80370 / delta like non-canonical Notch ligand 1ENSG0000018555932
CRB2 / Q5IJ48 / crumbs 2, cell polarity complex componentENSG0000014820430
CRB1 / P82279 / crumbs 1, cell polarity complex componentENSG0000013437629
SLIT1 / O75093 / slit guidance ligand 1ENSG0000018712228
SLIT3 / O75094 / slit guidance ligand 3ENSG0000018434727
SLIT2 / O94813 / slit guidance ligand 2ENSG0000014514726
DNER / Q8NFT8 / delta/notch like EGF repeat containingENSG0000018795722
DLL3 / Q9NYJ7 / delta like canonical Notch ligand 3ENSG0000009093219


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045598 regulation of fat cell differentiation IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr