ENSDARG00000037362


Danio rerio

Features
Gene ID: ENSDARG00000037362
  
Biological name :scube2
  
Synonyms : scube2 / signal peptide, CUB domain, EGF-like 2
  
Possible biological names infered from orthology : Q9JJS0 / Q9NQ36 / Signal peptide, CUB and EGF-like domain-containing protein 2 / signal peptide, CUB domain and EGF like domain containing 2
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 28569266
Gene end: 28611145
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000054365
NCBI entrez gene - 503728     See in Manteia.
RefSeq - XM_005166391
RefSeq - XM_021477521
RefSeq - NM_001014813
RefSeq - XM_005166390
RefSeq Peptide - NP_001014813
swissprot - F1Q6K4
ZFIN ID - ZDB-GENE-050302-80
Ensembl - ENSDARG00000037362
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SCUBE2ENSGALG00000032161Gallus gallus
 Q9NQ36ENSG00000175356Homo sapiens
 Q9JJS0ENSMUSG00000007279Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
scube1 / signal peptide, CUB domain, EGF-like 1 / Q6NZL8* / Q8IWY4* / signal peptide, CUB domain and EGF like domain containing 1*ENSDARG0000006309766
scube3 / signal peptide, CUB domain, EGF-like 3 / Q8IX30* / signal peptide, CUB domain and EGF like domain containing 3*ENSDARG0000001149059
cd248a / CD248 molecule, endosialin a / CD248* / Q9HCU0* / Q91V98* / Endosialin * / CD248 molecule*ENSDARG0000010371313
matn4 / matrilin 4 / Q8VCP9* / O95460* / Q86T13* / CLEC14A* / C-type lectin domain containing 14A* / C-type lectin domain family 14 member A *ENSDARG0000001594713
si:dkey-163f14.6ENSDARG0000009160212
cd248b / CD248 molecule, endosialin b / CD248* / Q9HCU0* / Q91V98* / Endosialin * / CD248 molecule*ENSDARG0000007793812
thbd / thrombomodulin / P07204* / P15306*ENSDARG0000009247011
matn1 / matrilin 1 / P21941* / P51942* / Cartilage matrix protein * / matrilin 1, cartilage matrix protein*ENSDARG000000302156
matn3a / matrilin 3a / MATN3* / O35701* / O15232* / matrilin 3*ENSDARG000000692453
matn3b / matrilin 3b / MATN3* / O35701* / O15232* / matrilin 3*ENSDARG000000692653
vwa1 / von Willebrand factor A domain containing 1 / Q6PCB0* / Q8R2Z5*ENSDARG000000754683


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR000859  CUB domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR024731  EGF domain
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000022 floor plate floor plate morphology , abnormal
floor plate quality , abnormal
Show

 ZFA:0000135 notochord notochord quality , abnormal
notochord morphology , abnormal
Show

 ZFA:0000155 somite somite U-shaped , abnormal
somite contractile fiber decreased amount , abnormal
somite quality , abnormal
somite morphology , abnormal
somite anterior region lacks parts or has fewer parts of type slow muscle cell , abnormal
somite has fewer parts of type muscle pioneer , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum hypoplastic , abnormal
horizontal myoseptum aplastic , abnormal
Show

 ZFA:0001056 myotome myotome U-shaped , abnormal
Show

 ZFA:0001089 myoseptum myoseptum quality , abnormal
Show

 ZFA:0001094 whole organism whole organism movement behavioral quality , abnormal
Show

 ZFA:0001115 trunk trunk muscle pioneer decreased amount , abnormal
trunk fast muscle cell decreased amount , abnormal
Show

 ZFA:0001117 post-vent region post-vent region contractile fiber patchy , abnormal
post-vent region slow muscle cell decreased amount , abnormal
post-vent region structure , abnormal
Show

 ZFA:0009091 melanocyte melanocyte quality , abnormal
melanocyte morphology , abnormal
melanocyte irregular spatial pattern , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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