ENSDARG00000030215


Danio rerio

Features
Gene ID: ENSDARG00000030215
  
Biological name :matn1
  
Synonyms : matn1 / matrilin 1
  
Possible biological names infered from orthology : Cartilage matrix protein / matrilin 1, cartilage matrix protein / P21941 / P51942
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 43314700
Gene end: 43338280
  
Corresponding Affymetrix probe sets: Dr.21066.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000049044
Ensembl peptide - ENSDARP00000114207
NCBI entrez gene - 403023     See in Manteia.
RefSeq - NM_001099740
RefSeq Peptide - NP_001093210
swissprot - A5WWJ5
swissprot - A5WWJ4
ZFIN ID - ZDB-GENE-050307-3
Ensembl - ENSDARG00000030215
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MATN1ENSGALG00000043185Gallus gallus
 MATN1ENSG00000162510Homo sapiens
 Matn1ENSMUSG00000040533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
matn4 / matrilin 4 / Q8VCP9* / O95460* / Q86T13* / CLEC14A* / C-type lectin domain containing 14A* / C-type lectin domain family 14 member A *ENSDARG0000001594752
matn3a / matrilin 3a / MATN3* / O35701* / O15232* / matrilin 3*ENSDARG0000006924528
matn3b / matrilin 3b / MATN3* / O35701* / O15232* / matrilin 3*ENSDARG0000006926525
vwa1 / von Willebrand factor A domain containing 1 / Q6PCB0* / Q8R2Z5*ENSDARG0000007546816
scube3 / signal peptide, CUB domain, EGF-like 3 / Q8IX30* / signal peptide, CUB domain and EGF like domain containing 3*ENSDARG0000001149012
scube2 / signal peptide, CUB domain, EGF-like 2 / Q9NQ36* / Q9JJS0* / signal peptide, CUB domain and EGF like domain containing 2* / Signal peptide, CUB and EGF-like domain-containing protein 2 *ENSDARG0000003736212
scube1 / signal peptide, CUB domain, EGF-like 1 / Q6NZL8* / Q8IWY4* / signal peptide, CUB domain and EGF like domain containing 1*ENSDARG0000006309711
cd248b / CD248 molecule, endosialin b / CD248* / Q9HCU0* / Q91V98* / Endosialin * / CD248 molecule*ENSDARG000000779389
thbd / thrombomodulin / P07204* / P15306*ENSDARG000000924709
cd248a / CD248 molecule, endosialin a / CD248* / Q9HCU0* / Q91V98* / Endosialin * / CD248 molecule*ENSDARG000001037139
si:dkey-163f14.6ENSDARG000000916026


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR002035  von Willebrand factor, type A
 IPR013032  EGF-like, conserved site
 IPR019466  Matrilin, coiled-coil trimerisation domain
 IPR030751  Matrilin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051216 cartilage development IMP
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord apoptotic DNA fragmentation increased process quality , abnormal
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 ZFA:0000106 extension extension shortened , abnormal
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 ZFA:0000107 eye eye apoptotic DNA fragmentation increased process quality , abnormal
eye decreased pigmentation , abnormal
Show

 ZFA:0000368 integument integument detached from whole organism , abnormal
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 ZFA:0001058 caudal fin caudal fin curved , abnormal
caudal fin deformed , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism decreased pigmentation , abnormal
Show

 ZFA:0001114 head head malformed , abnormal
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 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0001306 pharyngeal arch pharyngeal arch cartilage element immature , abnormal
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 ZFA:0001461 chondrocranium cartilage chondrocranium cartilage cartilage element immature , abnormal
Show

 ZFA:0001462 somite border somite border deformed , abnormal
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 ZFA:0009084 chondrocyte chondrocyte endoplasmic reticulum increased size , abnormal
chondrocyte endoplasmic reticulum disorganized , abnormal
chondrocyte endoplasmic reticulum lumen distended , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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