ENSDARG00000037997


Danio rerio

Features
Gene ID: ENSDARG00000037997
  
Biological name :tubb5
  
Synonyms : tubb5 / tubulin, beta 5
  
Possible biological names infered from orthology : P07437 / P99024 / TUBB / tubulin, beta 5 class I / tubulin beta class I
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 10318893
Gene end: 10327620
  
Corresponding Affymetrix probe sets: Dr.4416.1.A1_at (Zebrafish Array)   Dr.4416.3.A1_at (Zebrafish Array)   NM_198818_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000055379
NCBI entrez gene - 386701     See in Manteia.
RefSeq - XM_005173471
RefSeq - NM_198818
RefSeq Peptide - NP_942113
swissprot - Q6NW90
ZFIN ID - ZDB-GENE-031110-4
Ensembl - ENSDARG00000037997
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TUBBENSG00000196230Homo sapiens
 Tubb5ENSMUSG00000001525Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tubb4b / tubulin, beta 4B class IVbENSDARG0000000234498
zgc:153426ENSDARG0000010443698
zgc:55461 / P04350* / Q9D6F9* / TUBB4A* / tubulin beta 4A class IVa*ENSDARG0000004172397
tubb2b / tubulin, beta 2b / Q9D6F9* / P04350* / TUBB4A* / tubulin beta 4A class IVa*ENSDARG0000009859197
zgc:65894ENSDARG0000001630196
tubb2 / tubulin, beta 2A class IIa / Q9BVA1* / Q9CWF2* / Q13885* / TUBB2A* / TUBB2B* / Q7TMM9* / tubulin beta 2B class IIb*ENSDARG0000003952294
tubb6 / tubulin, beta 6 class V / Q922F4* / Q9BUF5*ENSDARG0000010480190
tubb1 / tubulin, beta 1 class VI / A2AQ07* / Q9H4B7*ENSDARG0000005306682
tube1 / tubulin, epsilon 1 / Q9D6T1* / Q9UJT0* / epsilon-tubulin 1*ENSDARG0000009662033
tube1 / tubulin, epsilon 1 / Q9D6T1* / Q9UJT0* / epsilon-tubulin 1*ENSDARG0000004398233
tubd1 / tubulin, delta 1 / Q9R1K7* / Q9UJT1*ENSDARG0000005821923


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002453  Beta tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR013838  Beta tubulin, autoregulation binding site
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007017 microtubule-based process IEA
 biological_processGO:0031101 fin regeneration IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton NAS
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005198 structural molecule activity NAS
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Neutrophil degranulation
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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