ENSDARG00000098591


Danio rerio

Features
Gene ID: ENSDARG00000098591
  
Biological name :tubb2b
  
Synonyms : tubb2b / tubulin, beta 2b
  
Possible biological names infered from orthology : P04350 / Q9D6F9 / TUBB4A / tubulin beta 4A class IVa
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 52713232
Gene end: 52715911
  
Corresponding Affymetrix probe sets: Dr.5605.3.S1_at (Zebrafish Array)   Dr.5605.3.S1_x_at (Zebrafish Array)   NM_001037410_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000137515
NCBI entrez gene - 641421     See in Manteia.
RefSeq - NM_001037410
RefSeq Peptide - NP_001032487
swissprot - A0A0R4IPH2
ZFIN ID - ZDB-GENE-030131-722
Ensembl - ENSDARG00000098591
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P04350ENSG00000104833Homo sapiens
 Q9D6F9ENSMUSG00000062591Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tubb4b / tubulin, beta 4B class IVbENSDARG0000000234499
zgc:55461 / P04350* / Q9D6F9* / TUBB4A* / tubulin beta 4A class IVa*ENSDARG0000004172399
zgc:153426ENSDARG0000010443698
zgc:65894ENSDARG0000001630197
tubb5 / tubulin, beta 5 / TUBB* / P99024* / P07437* / tubulin beta class I* / tubulin, beta 5 class I*ENSDARG0000003799796
tubb2 / tubulin, beta 2A class IIa / Q9BVA1* / Q9CWF2* / Q13885* / TUBB2A* / TUBB2B* / Q7TMM9* / tubulin beta 2B class IIb*ENSDARG0000003952294
tubb6 / tubulin, beta 6 class V / Q922F4* / Q9BUF5*ENSDARG0000010480190
tubb1 / tubulin, beta 1 class VI / A2AQ07* / Q9H4B7*ENSDARG0000005306683
tube1 / tubulin, epsilon 1 / Q9D6T1* / Q9UJT0* / epsilon-tubulin 1*ENSDARG0000004398234
tube1 / tubulin, epsilon 1 / Q9D6T1* / Q9UJT0* / epsilon-tubulin 1*ENSDARG0000009662034
tubd1 / tubulin, delta 1 / Q9R1K7* / Q9UJT1*ENSDARG0000005821924


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002453  Beta tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR013838  Beta tubulin, autoregulation binding site
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007017 microtubule-based process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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