ENSDARG00000045641


Danio rerio

Features
Gene ID: ENSDARG00000045641
  
Biological name :usp3
  
Synonyms : ubiquitin specific peptidase 3 / usp3
  
Possible biological names infered from orthology : Q91W36 / Q9Y6I4
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 26738450
Gene end: 26753196
  
Corresponding Affymetrix probe sets: Dr.6883.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000129176
NCBI entrez gene - 569679     See in Manteia.
RefSeq - NM_001199871
RefSeq Peptide - NP_001186800
swissprot - X1WG21
ZFIN ID - ZDB-GENE-030131-5142
Ensembl - ENSDARG00000045641
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USP3ENSGALG00000003427Gallus gallus
 USP3ENSG00000140455Homo sapiens
 Usp3ENSMUSG00000032376Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
usp44 / ubiquitin specific peptidase 44 / Q9H0E7*ENSDARG0000008986133
usp49 / ubiquitin specific peptidase 49 / Q6P9L4* / Q70CQ1*ENSDARG0000000022931
usp22 / A6H8I0 / ubiquitin specific peptidase 22 / USP51* / Q70EK9* / Q8CEG8* / Q9UPT9* / B1AY15* / Q5DU02* / A6NNY8* / USP27X* / ubiquitin specific protease 51* / ubiquitin specific peptid...ENSDARG0000004040726
usp36 / ubiquitin specific peptidase 36 / B1AQJ2* / Q9P275*ENSDARG0000003232721
usp42 / ubiquitin specific peptidase 42 / B2RQC2* / Q9H9J4*ENSDARG0000007730021


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000155 somite somite fused with somite , abnormal
Show

 ZFA:0000445 optic tectum optic tectum increased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk decreased thickness , abnormal
trunk bent , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curled , abnormal
Show

 ZFA:0001604 caudal fin upper lobe caudal fin upper lobe fused with caudal fin lower lobe , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr