ENSDARG00000052405


Danio rerio

Features
Gene ID: ENSDARG00000052405
  
Biological name :pak6b
  
Synonyms : p21 protein (Cdc42/Rac)-activated kinase 6b / pak6b
  
Possible biological names infered from orthology : BUB1B-PAK6 / BUB1B-PAK6 readthrough / p21 (RAC1) activated kinase 6 / PAK6 / Q3ULB5 / Q9NQU5 / Serine/threonine-protein kinase PAK 6
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 53521648
Gene end: 53568849
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000090883
Ensembl peptide - ENSDARP00000114247
Ensembl peptide - ENSDARP00000113873
NCBI entrez gene - 567874     See in Manteia.
RefSeq - NM_001162487
RefSeq Peptide - NP_001155959
swissprot - A8DZ62
swissprot - A5PEY8
ZFIN ID - ZDB-GENE-041014-121
Ensembl - ENSDARG00000052405
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000034605Gallus gallus
 BUB1B-PAK6ENSG00000259288Homo sapiens
 PAK6ENSG00000137843Homo sapiens
 Pak6ENSMUSG00000074923Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pak6a / p21 protein (Cdc42/Rac)-activated kinase 6a / PAK6* / Q9NQU5* / BUB1B-PAK6* / BUB1B-PAK6 readthrough* / p21 (RAC1) activated kinase 6*ENSDARG0000002756466
pak4 / p21 protein (Cdc42/Rac)-activated kinase 4 / Q8BTW9* / O96013* / p21 (RAC1) activated kinase 4* / Serine/threonine-protein kinase PAK 4 *ENSDARG0000001811046
pak7 / p21 protein (Cdc42/Rac)-activated kinase 7 / PAK5* / Q8C015* / Q9P286* / p21 (RAC1) activated kinase 5* / Serine/threonine-protein kinase PAK 5 *ENSDARG0000003015442
pak1 / p21 protein (Cdc42/Rac)-activated kinase 1ENSDARG0000010395929
pak2b / p21 protein (Cdc42/Rac)-activated kinase 2b / PAK2* / Q13177* / Q8CIN4* / p21 (RAC1) activated kinase 2* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*ENSDARG0000001847628
pak2a / p21 protein (Cdc42/Rac)-activated kinase 2a / PAK2* / Q13177* / Q8CIN4* / p21 (RAC1) activated kinase 2* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*ENSDARG0000006817728
taok3a / TAO kinase 3a / TAOK3* / Q9H2K8* / Q8BYC6* / TAO kinase 3*ENSDARG0000006075118
taok1b / TAO kinase 1b / TAOK1* / Q7L7X3* / Q5F2E8* / TAO kinase 1*ENSDARG0000009830418
taok1a / TAO kinase 1a / TAOK1* / Q7L7X3* / Q5F2E8* / TAO kinase 1*ENSDARG0000006960318
taok2a / TAO kinase 2a / TAOK2* / Q9UL54* / Q6ZQ29* / TAO kinase 2* / Serine/threonine-protein kinase TAO2 *ENSDARG0000007489917
taok2b / TAO kinase 2b / TAOK2* / Q9UL54* / Q6ZQ29* / TAO kinase 2* / Serine/threonine-protein kinase TAO2 *ENSDARG0000010062017
taok3b / TAO kinase 3bENSDARG000000940521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR033923  p21 activated kinase binding domain
 IPR035066  Serine/threonine-protein kinase PAK 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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