ENSG00000259288


Homo sapiens

Features
Gene ID: ENSG00000259288
  
Biological name :BUB1B-PAK6
  
Synonyms : BUB1B-PAK6 / BUB1B-PAK6 readthrough
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q15.1
Gene start: 40217428
Gene end: 40276396
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000406873
Ensembl peptide - ENSP00000457109
Ensembl peptide - ENSP00000456785
Ensembl peptide - ENSP00000401153
NCBI entrez gene - 106821730     See in Manteia.
RefSeq - NM_001128628
RefSeq Peptide - NP_001122100
swissprot - A0A0U1RQB7
swissprot - A0A024R9Q4
swissprot - H3BSN5
swissprot - H3BTB9
Ensembl - ENSG00000259288
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pak6aENSDARG00000027564Danio rerio
 pak6bENSDARG00000052405Danio rerio
 ENSGALG00000034605Gallus gallus
 Pak6ENSMUSG00000074923Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PAK6 / Q9NQU5 / p21 (RAC1) activated kinase 6ENSG00000137843100
PAK5 / Q9P286 / p21 (RAC1) activated kinase 5ENSG0000010134949
PAK4 / O96013 / p21 (RAC1) activated kinase 4ENSG0000013066947
PAK1 / Q13153 / p21 (RAC1) activated kinase 1ENSG0000014926928
PAK3 / O75914 / p21 (RAC1) activated kinase 3ENSG0000007726428
PAK2 / Q13177 / p21 (RAC1) activated kinase 2ENSG0000018037028
TAOK1 / Q7L7X3 / TAO kinase 1ENSG0000016055117
TAOK3 / Q9H2K8 / TAO kinase 3ENSG0000013509017
TAOK2 / Q9UL54 / TAO kinase 2ENSG0000014993017


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR033923  p21 activated kinase binding domain
 IPR035066  Serine/threonine-protein kinase PAK 6
 IPR036936  CRIB domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007094 mitotic spindle assembly checkpoint IEA
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0030054 cell junction IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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