ENSG00000149930


Homo sapiens

Features
Gene ID: ENSG00000149930
  
Biological name :TAOK2
  
Synonyms : Q9UL54 / TAOK2 / TAO kinase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 29973641
Gene end: 29992261
  
Corresponding Affymetrix probe sets: 204877_s_at (Human Genome U133 Plus 2.0 Array)   204878_s_at (Human Genome U133 Plus 2.0 Array)   204986_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000279394
Ensembl peptide - ENSP00000310094
Ensembl peptide - ENSP00000393048
Ensembl peptide - ENSP00000440336
NCBI entrez gene - 9344     See in Manteia.
OMIM - 613199
RefSeq - XM_011545986
RefSeq - NM_001252043
RefSeq - NM_004783
RefSeq - NM_016151
RefSeq - XM_011545982
RefSeq - XM_011545983
RefSeq - XM_011545984
RefSeq - XM_011545985
RefSeq Peptide - NP_004774
RefSeq Peptide - NP_057235
RefSeq Peptide - NP_001238972
swissprot - Q9UL54
Ensembl - ENSG00000149930
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taok2aENSDARG00000074899Danio rerio
 taok2bENSDARG00000100620Danio rerio
 Taok2ENSMUSG00000059981Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAOK1 / Q7L7X3 / TAO kinase 1ENSG0000016055149
TAOK3 / Q9H2K8 / TAO kinase 3ENSG0000013509041
PAK3 / O75914 / p21 (RAC1) activated kinase 3ENSG0000007726410
PAK2 / Q13177 / p21 (RAC1) activated kinase 2ENSG0000018037010
PAK1 / Q13153 / p21 (RAC1) activated kinase 1ENSG0000014926910
PAK5 / Q9P286 / p21 (RAC1) activated kinase 5ENSG000001013499
PAK4 / O96013 / p21 (RAC1) activated kinase 4ENSG000001306699
PAK6 / Q9NQU5 / p21 (RAC1) activated kinase 6ENSG000001378439
BUB1B-PAK6 / BUB1B-PAK6 readthroughENSG000002592889


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity IDA
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0001558 regulation of cell growth NAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006612 protein targeting to membrane NAS
 biological_processGO:0006915 apoptotic process NAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IMP
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0007409 axonogenesis ISS
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration NAS
 biological_processGO:0030036 actin cytoskeleton organization IDA
 biological_processGO:0031954 positive regulation of protein autophosphorylation TAS
 biological_processGO:0032147 activation of protein kinase activity TAS
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IMP
 biological_processGO:0032956 regulation of actin cytoskeleton organization ISS
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0046330 positive regulation of JNK cascade ISS
 biological_processGO:0046777 protein autophosphorylation TAS
 biological_processGO:0048041 focal adhesion assembly IDA
 biological_processGO:0051403 stress-activated MAPK cascade IDA
 biological_processGO:0150019 basal dendrite morphogenesis ISS
 biological_processGO:0150020 basal dendrite arborization ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:0044294 dendritic growth cone ISS
 cellular_componentGO:0044295 axonal growth cone ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity NAS
 molecular_functionGO:0004709 MAP kinase kinase kinase activity NAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IPI
 molecular_functionGO:0038191 neuropilin binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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