ENSG00000135090


Homo sapiens

Features
Gene ID: ENSG00000135090
  
Biological name :TAOK3
  
Synonyms : Q9H2K8 / TAOK3 / TAO kinase 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.23
Gene start: 118149801
Gene end: 118372945
  
Corresponding Affymetrix probe sets: 220761_s_at (Human Genome U133 Plus 2.0 Array)   221508_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444057
Ensembl peptide - ENSP00000443487
Ensembl peptide - ENSP00000443834
Ensembl peptide - ENSP00000376317
Ensembl peptide - ENSP00000416374
Ensembl peptide - ENSP00000437389
Ensembl peptide - ENSP00000438766
Ensembl peptide - ENSP00000438820
Ensembl peptide - ENSP00000439620
Ensembl peptide - ENSP00000440315
Ensembl peptide - ENSP00000441071
Ensembl peptide - ENSP00000441932
Ensembl peptide - ENSP00000442541
Ensembl peptide - ENSP00000443465
NCBI entrez gene - 51347     See in Manteia.
OMIM - 616711
RefSeq - XM_017019413
RefSeq - NM_001346489
RefSeq - NM_016281
RefSeq - XM_005253897
RefSeq - XM_005253898
RefSeq - XM_006719445
RefSeq - XM_011538437
RefSeq - XM_011538439
RefSeq - XM_017019408
RefSeq - XM_017019409
RefSeq - XM_017019410
RefSeq - XM_017019411
RefSeq - XM_017019412
RefSeq Peptide - NP_001333417
RefSeq Peptide - NP_001333418
RefSeq Peptide - NP_057365
swissprot - F5H005
swissprot - F5H0M3
swissprot - F5H1I2
swissprot - F5H3L7
swissprot - F5H5C7
swissprot - F5H5E0
swissprot - F5H7G4
swissprot - G3V1Q8
swissprot - H0YF68
swissprot - F5GWV8
swissprot - Q9H2K8
swissprot - F5GX96
swissprot - F5GY38
Ensembl - ENSG00000135090
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taok3aENSDARG00000060751Danio rerio
 TAOK3ENSGALG00000007396Gallus gallus
 Taok3ENSMUSG00000061288Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAOK1 / Q7L7X3 / TAO kinase 1ENSG0000016055173
TAOK2 / Q9UL54 / TAO kinase 2ENSG0000014993057
BUB1B-PAK6 / BUB1B-PAK6 readthroughENSG0000025928813
PAK3 / O75914 / p21 (RAC1) activated kinase 3ENSG0000007726413
PAK4 / O96013 / p21 (RAC1) activated kinase 4ENSG0000013066913
PAK1 / Q13153 / p21 (RAC1) activated kinase 1ENSG0000014926913
PAK2 / Q13177 / p21 (RAC1) activated kinase 2ENSG0000018037013
PAK6 / Q9NQU5 / p21 (RAC1) activated kinase 6ENSG0000013784313
PAK5 / Q9P286 / p21 (RAC1) activated kinase 5ENSG0000010134913


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IMP
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IMP
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IMP
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043507 positive regulation of JUN kinase activity IMP
 biological_processGO:0046329 negative regulation of JNK cascade IDA
 biological_processGO:0046330 positive regulation of JNK cascade IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004860 protein kinase inhibitor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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