ENSMUSG00000061288


Mus musculus

Features
Gene ID: ENSMUSG00000061288
  
Biological name :Taok3
  
Synonyms : Q8BYC6 / Taok3 / TAO kinase 3
  
Possible biological names infered from orthology : Q9H2K8
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 117120129
Gene end: 117275219
  
Corresponding Affymetrix probe sets: 10524844 (MoGene1.0st)   1435964_a_at (Mouse Genome 430 2.0 Array)   1444881_at (Mouse Genome 430 2.0 Array)   1448019_at (Mouse Genome 430 2.0 Array)   1455733_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119998
Ensembl peptide - ENSMUSP00000117841
Ensembl peptide - ENSMUSP00000136750
Ensembl peptide - ENSMUSP00000090565
Ensembl peptide - ENSMUSP00000107606
Ensembl peptide - ENSMUSP00000107609
Ensembl peptide - ENSMUSP00000116920
NCBI entrez gene - 330177     See in Manteia.
MGI - MGI:3041177
RefSeq - XM_011248221
RefSeq - NM_001081308
RefSeq - NM_001199685
RefSeq - NM_183306
RefSeq - XM_006530385
RefSeq - XM_011248219
RefSeq - XM_011248220
RefSeq Peptide - NP_001186614
RefSeq Peptide - NP_899129
RefSeq Peptide - NP_001074777
swissprot - E9Q364
swissprot - Q3V3K3
swissprot - Q8BYC6
swissprot - A0A0R4J1T3
swissprot - F6RXB5
Ensembl - ENSMUSG00000061288
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taok3aENSDARG00000060751Danio rerio
 TAOK3ENSGALG00000007396Gallus gallus
 TAOK3ENSG00000135090Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Taok1 / Q5F2E8 / TAO kinase 1 / Q7L7X3*ENSMUSG0000001729173
Taok2 / Q6ZQ29 / Serine/threonine-protein kinase TAO2 / Q9UL54* / TAO kinase 2*ENSMUSG0000005998156
Pak6 / Q3ULB5 / Serine/threonine-protein kinase PAK 6 / Q9NQU5* / BUB1B-PAK6* / BUB1B-PAK6 readthrough* / p21 (RAC1) activated kinase 6*ENSMUSG0000007492313
Pak3 / Q61036 / Serine/threonine-protein kinase PAK 3 / O75914* / p21 (RAC1) activated kinase 3*ENSMUSG0000003128413
Pak1 / Mus musculus p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), transcript variant 3, mRNA. / Q13153* / p21 (RAC1) activated kinase 1*ENSMUSG0000003077413
Pak2 / Q8CIN4 / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34 / Q13177* / p21 (RAC1) activated kinase 2*ENSMUSG0000002278113
Pak7 / Q8C015 / Serine/threonine-protein kinase PAK 5 / PAK5* / Q9P286* / p21 (RAC1) activated kinase 5*ENSMUSG0000003991313
Pak4 / Q8BTW9 / Serine/threonine-protein kinase PAK 4 / O96013* / p21 (RAC1) activated kinase 4*ENSMUSG0000003060213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade ISO
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint ISO
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade ISS
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043507 positive regulation of JUN kinase activity ISO
 biological_processGO:0046329 negative regulation of JNK cascade ISO
 biological_processGO:0046330 positive regulation of JNK cascade ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0097194 execution phase of apoptosis IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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