ENSMUSG00000017291


Mus musculus

Features
Gene ID: ENSMUSG00000017291
  
Biological name :Taok1
  
Synonyms : Q5F2E8 / Taok1 / TAO kinase 1
  
Possible biological names infered from orthology : Q7L7X3
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B5
Gene start: 77529162
Gene end: 77607815
  
Corresponding Affymetrix probe sets: 10388682 (MoGene1.0st)   10388684 (MoGene1.0st)   1424657_at (Mouse Genome 430 2.0 Array)   1424658_at (Mouse Genome 430 2.0 Array)   1426357_at (Mouse Genome 430 2.0 Array)   1426358_at (Mouse Genome 430 2.0 Array)   1455432_at (Mouse Genome 430 2.0 Array)   1456975_at (Mouse Genome 430 2.0 Array)   1459770_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000017435
Ensembl peptide - ENSMUSP00000055470
NCBI entrez gene - 216965     See in Manteia.
MGI - MGI:1914490
RefSeq - XM_011248931
RefSeq - NM_144825
RefSeq - XM_006532960
RefSeq - XM_011248929
RefSeq - XM_011248930
RefSeq - XM_006532958
RefSeq - XM_006532959
RefSeq Peptide - NP_659074
swissprot - Q5F2E8
swissprot - B2RX66
Ensembl - ENSMUSG00000017291
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taok1aENSDARG00000069603Danio rerio
 taok1bENSDARG00000098304Danio rerio
 TAOK1ENSGALG00000004082Gallus gallus
 TAOK1ENSG00000160551Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Taok3 / Q8BYC6 / TAO kinase 3 / Q9H2K8*ENSMUSG0000006128865
Taok2 / Q6ZQ29 / Serine/threonine-protein kinase TAO2 / Q9UL54* / TAO kinase 2*ENSMUSG0000005998160
Pak3 / Q61036 / Serine/threonine-protein kinase PAK 3 / O75914* / p21 (RAC1) activated kinase 3*ENSMUSG0000003128413
Pak1 / Mus musculus p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), transcript variant 3, mRNA. / Q13153* / p21 (RAC1) activated kinase 1*ENSMUSG0000003077413
Pak2 / Q8CIN4 / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34 / Q13177* / p21 (RAC1) activated kinase 2*ENSMUSG0000002278112
Pak4 / Q8BTW9 / Serine/threonine-protein kinase PAK 4 / O96013* / p21 (RAC1) activated kinase 4*ENSMUSG0000003060212
Pak6 / Q3ULB5 / Serine/threonine-protein kinase PAK 6 / Q9NQU5* / BUB1B-PAK6* / BUB1B-PAK6 readthrough* / p21 (RAC1) activated kinase 6*ENSMUSG0000007492311
Pak7 / Q8C015 / Serine/threonine-protein kinase PAK 5 / PAK5* / Q9P286* / p21 (RAC1) activated kinase 5*ENSMUSG0000003991311


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint ISO
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade ISS
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0046330 positive regulation of JNK cascade ISS
 biological_processGO:0051493 regulation of cytoskeleton organization ISS
 biological_processGO:0097194 execution phase of apoptosis ISS
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISS
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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