ENSDARG00000056554


Danio rerio

Features
Gene ID: ENSDARG00000056554
  
Biological name :rap1gap
  
Synonyms : rap1gap / RAP1 GTPase activating protein
  
Possible biological names infered from orthology : A2ALS5 / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA. / P47736
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 22267374
Gene end: 22425257
  
Corresponding Affymetrix probe sets: Dr.26323.1.A1_at (Zebrafish Array)   Dr.26401.1.S1_at (Zebrafish Array)   Dr.4316.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000073491
Ensembl peptide - ENSDARP00000114327
NCBI entrez gene - 100144557     See in Manteia.
RefSeq - NM_001123053
RefSeq Peptide - NP_001116525
swissprot - F1QIU1
swissprot - A0A0A0MPJ2
ZFIN ID - ZDB-GENE-080402-9
Ensembl - ENSDARG00000056554
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAP1GAP1ENSGALG00000014701Gallus gallus
 P47736ENSG00000076864Homo sapiens
 A2ALS5ENSMUSG00000041351Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-166d12.2 / P47736* / RAP1GAP* / RAP1 GTPase activating protein*ENSDARG0000005327276
rap1gap2b / RAP1 GTPase activating protein 2b / Q5SVL6* / Q684P5* / RAP1GAP2* / RAP1 GTPase activating protein 2*ENSDARG0000007422246
rap1gap2a / RAP1 GTPase activating protein 2a / Q5SVL6* / Q684P5* / RAP1GAP2* / RAP1 GTPase activating protein 2*ENSDARG0000006155140
si:ch1073-90m23.1ENSDARG0000009157333
sipa1l3 / signal-induced proliferation-associated 1 like 3 / G3X9J0* / O60292*ENSDARG0000006169929
sipa1l1 / signal-induced proliferation-associated 1 like 1 / O43166* / Q8C0T5* / Signal-induced proliferation-associated 1-like protein 1 *ENSDARG0000002013429
sipa1l2 / signal-induced proliferation-associated 1 like 2 / Q80TE4* / Q9P2F8* / Mus musculus signal-induced proliferation-associated 1 like 2 (Sipa1l2), transcript variant 2, mRNA.*ENSDARG0000006164027
A5PF44 / si:ch211-182d3.1 / GARNL3* / Q5VVW2* / GTPase activating Rap/RanGAP domain like 3*ENSDARG0000006063125
zmp:0000001168 / SIPA1* / Q96FS4* / signal-induced proliferation-associated 1*ENSDARG0000007669722
ralgapa2 / Ral GTPase activating protein, alpha subunit 2 (catalytic) / Q2PPJ7* / A3KGS3* / Ral GTPase-activating protein subunit alpha-2 * / Ral GTPase activating protein catalytic alpha subunit 2*ENSDARG0000000586114
ralgapa1 / Ral GTPase activating protein, alpha subunit 1 (catalytic) / Q6GYQ0* / Q6GYP7* / Ral GTPase activating protein, alpha subunit 1* / Ral GTPase activating protein catalytic alpha subunit 1*ENSDARG0000007688913
tsc2 / TSC complex subunit 2ENSDARG000001031258
CABZ01067150.1ENSDARG000001161221


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain
 IPR003109  GoLoco motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0030695 GTPase regulator activity IEA


Pathways (from Reactome)
Pathway description
Rap1 signalling
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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