ENSDARG00000061551


Danio rerio

Features
Gene ID: ENSDARG00000061551
  
Biological name :rap1gap2a
  
Synonyms : rap1gap2a / RAP1 GTPase activating protein 2a
  
Possible biological names infered from orthology : Q5SVL6 / Q684P5 / RAP1GAP2 / RAP1 GTPase activating protein 2
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 29276508
Gene end: 29317067
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000110618
Ensembl peptide - ENSDARP00000131877
Ensembl peptide - ENSDARP00000120602
Ensembl peptide - ENSDARP00000090668
NCBI entrez gene - 561339     See in Manteia.
RefSeq - NM_001326443
RefSeq - NM_001326442
RefSeq Peptide - NP_001313371
RefSeq Peptide - NP_001313372
swissprot - E7F869
swissprot - A3KNF9
swissprot - F1QBC6
ZFIN ID - ZDB-GENE-061013-179
Ensembl - ENSDARG00000061551
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAP1GAP2ENSGALG00000033885Gallus gallus
 Q684P5ENSG00000132359Homo sapiens
 Q5SVL6ENSMUSG00000038807Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rap1gap2b / RAP1 GTPase activating protein 2b / Q5SVL6* / Q684P5* / RAP1GAP2* / RAP1 GTPase activating protein 2*ENSDARG0000007422265
rap1gap / RAP1 GTPase activating protein / A2ALS5* / P47736* / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA.*ENSDARG0000005655459
si:dkey-166d12.2 / P47736* / RAP1GAP* / RAP1 GTPase activating protein*ENSDARG0000005327256
si:ch1073-90m23.1ENSDARG0000009157341
sipa1l1 / signal-induced proliferation-associated 1 like 1 / O43166* / Q8C0T5* / Signal-induced proliferation-associated 1-like protein 1 *ENSDARG0000002013431
sipa1l3 / signal-induced proliferation-associated 1 like 3 / G3X9J0* / O60292*ENSDARG0000006169931
zmp:0000001168 / SIPA1* / Q96FS4* / signal-induced proliferation-associated 1*ENSDARG0000007669730
sipa1l2 / signal-induced proliferation-associated 1 like 2 / Q80TE4* / Q9P2F8* / Mus musculus signal-induced proliferation-associated 1 like 2 (Sipa1l2), transcript variant 2, mRNA.*ENSDARG0000006164030
A5PF44 / si:ch211-182d3.1 / GARNL3* / Q5VVW2* / GTPase activating Rap/RanGAP domain like 3*ENSDARG0000006063128
ralgapa2 / Ral GTPase activating protein, alpha subunit 2 (catalytic) / Q2PPJ7* / A3KGS3* / Ral GTPase-activating protein subunit alpha-2 * / Ral GTPase activating protein catalytic alpha subunit 2*ENSDARG0000000586112
ralgapa1 / Ral GTPase activating protein, alpha subunit 1 (catalytic) / Q6GYQ0* / Q6GYP7* / Ral GTPase activating protein, alpha subunit 1* / Ral GTPase activating protein catalytic alpha subunit 1*ENSDARG0000007688911
tsc2 / TSC complex subunit 2ENSDARG000001031259
CABZ01067150.1ENSDARG000001161221


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 molecular_functionGO:0005096 GTPase activator activity IEA


Pathways (from Reactome)
Pathway description
Rap1 signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000031702 prkg1b / protein kinase, cGMP-dependent, type Ib / PRKG1* / P0C605* / Q13976* / protein kinase, cGMP-dependent, type I*  / reaction
 ENSDARG00000059125 prkacbb / protein kinase, cAMP-dependent, catalytic, beta b / P22694* / PRKACB* / protein kinase cAMP-activated catalytic subunit beta*  / reaction
 ENSDARG00000013078 ywhaba / Q5PRD0 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a / YWHAB* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activat...  / reaction / complex
 ENSDARG00000012553 rap1aa / RAP1A, member of RAS oncogene family a / RAP1B* / Q99JI6* / P61224* / RAS related protein 1b* / RAP1B, member of RAS oncogene family*  / reaction
 ENSDARG00000087346 rap1ab / RAP1A, member of RAS oncogene family b / RAP1B* / Q99JI6* / P61224* / RAS related protein 1b* / RAP1B, member of RAS oncogene family*  / reaction
 ENSDARG00000008867 rap1b / Q6TEN1 / RAP1B, member of RAS oncogene family / Q99JI6* / P61224* / RAS related protein 1b*  / reaction






 

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