ENSGALG00000033885


Gallus gallus

Features
Gene ID: ENSGALG00000033885
  
Biological name :RAP1GAP2
  
Synonyms : RAP1GAP2 / rap1 GTPase-activating protein 2
  
Possible biological names infered from orthology : Q5SVL6 / Q684P5
  
Species: Gallus gallus
  
Chr. number: 19
Strand: 1
Band:
Gene start: 9545881
Gene end: 9595390
  
Corresponding Affymetrix probe sets: GgaAffx.12594.1.S1_at (Chicken Array)   GgaAffx.3667.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044591
Ensembl peptide - ENSGALP00000055176
Ensembl peptide - ENSGALP00000051088
Ensembl peptide - ENSGALP00000047532
NCBI entrez gene - 427841     See in Manteia.
RefSeq - XM_015295821
RefSeq - XM_015295816
RefSeq - XM_015295817
RefSeq - XM_015295818
RefSeq - XM_015295819
RefSeq - XM_015295820
RefSeq - NM_001031478
RefSeq - XM_015295815
RefSeq Peptide - NP_001026649
swissprot - A0A1D5PQL1
swissprot - A0A1D5PE87
swissprot - A0A1D5P4C4
swissprot - A0A1D5NW55
Ensembl - ENSGALG00000033885
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rap1gap2aENSDARG00000061551Danio rerio
 rap1gap2bENSDARG00000074222Danio rerio
 Q684P5ENSG00000132359Homo sapiens
 Q5SVL6ENSMUSG00000038807Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAP1GAP1 / RAP1 GTPase activating protein / P47736* / A2ALS5* / RAP1GAP* / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA.*ENSGALG0000001470137
SIPA1L1 / O43166* / Q8C0T5* / signal induced proliferation associated 1 like 1* / Signal-induced proliferation-associated 1-like protein 1 *ENSGALG0000000938128
SIPA1L2 / signal induced proliferation associated 1 like 2 / Q80TE4* / Q9P2F8* / Mus musculus signal-induced proliferation-associated 1 like 2 (Sipa1l2), transcript variant 2, mRNA.*ENSGALG0000003750626
GARNL3 / GTPase-activating Rap/Ran-GAP domain-like protein 3 / Q3V0G7* / Q5VVW2* / GTPase activating Rap/RanGAP domain like 3* / Mus musculus GTPase activating RANGAP domain-like 3 (Garnl3...ENSGALG0000000084723
RALGAPA1 / ral GTPase-activating protein subunit alpha-1 isoform 3 / Q6GYQ0* / Q6GYP7* / Ral GTPase activating protein, alpha subunit 1* / Ral GTPase activating protein catalytic alpha subunit 1*ENSGALG0000001008813
TSC2 / TSC complex subunit 2 / P49815* / tuberous sclerosis 2*ENSGALG0000000564610
A3KGS3* / Q2PPJ7* / RALGAPA2* / Ral GTPase-activating protein subunit alpha-2 * / Ral GTPase activating protein catalytic alpha subunit 2*ENSGALG000000447304
A3KGS3* / Q2PPJ7* / RALGAPA2* / Ral GTPase-activating protein subunit alpha-2 * / Ral GTPase activating protein catalytic alpha subunit 2*ENSGALG000000329642


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008361 regulation of cell size IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0005096 GTPase activator activity IEA


Pathways (from Reactome)
Pathway description
Rap1 signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003805 PRKG1 / protein kinase, cGMP-dependent, type I / P0C605* / Q13976*  / reaction
 ENSGALG00000004143 YWHAB / Q5ZLQ6 / 14-3-3 protein beta/alpha / Q9CQV8* / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta* / tyrosine 3-monooxygenase/tryptophan 5-monoox...  / complex / reaction
 ENSGALG00000031387 YWHAZ / Q5ZKC9 / 14-3-3 protein zeta / P63104* / P63101* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenas...  / complex / reaction
 ENSGALG00000001476 RAP1A / RAP1A, member of RAS oncogene family / P62834* / P62835* / RAS-related protein 1a*  / reaction
 ENSGALG00000009927 RAP1B / Q5ZHX1 / Ras-related protein Rap-1b / Q99JI6* / P61224* / RAS related protein 1b* / RAP1B, member of RAS oncogene family*  / reaction






 

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