ENSGALG00000014701


Gallus gallus

Features
Gene ID: ENSGALG00000014701
  
Biological name :RAP1GAP1
  
Synonyms : RAP1GAP1 / RAP1 GTPase activating protein
  
Possible biological names infered from orthology : A2ALS5 / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA. / P47736 / RAP1GAP
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 77714268
Gene end: 77753043
  
Corresponding Affymetrix probe sets: Gga.2753.1.S1_at (Chicken Array)   Gga.2753.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036270
NCBI entrez gene - 395647     See in Manteia.
RefSeq - XM_015293180
RefSeq - NM_204843
RefSeq - XM_015293174
RefSeq - XM_015293176
RefSeq - XM_015293172
RefSeq Peptide - NP_990174
swissprot - Q9PWA2
Ensembl - ENSGALG00000014701
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rap1gapENSDARG00000056554Danio rerio
 si:dkey-166d12.2ENSDARG00000053272Danio rerio
 P47736ENSG00000076864Homo sapiens
 A2ALS5ENSMUSG00000041351Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAP1GAP2 / rap1 GTPase-activating protein 2 / Q5SVL6* / Q684P5*ENSGALG0000003388553
SIPA1L2 / signal induced proliferation associated 1 like 2 / Q80TE4* / Q9P2F8* / Mus musculus signal-induced proliferation-associated 1 like 2 (Sipa1l2), transcript variant 2, mRNA.*ENSGALG0000003750630
SIPA1L1 / O43166* / Q8C0T5* / signal induced proliferation associated 1 like 1* / Signal-induced proliferation-associated 1-like protein 1 *ENSGALG0000000938130
GARNL3 / GTPase-activating Rap/Ran-GAP domain-like protein 3 / Q3V0G7* / Q5VVW2* / GTPase activating Rap/RanGAP domain like 3* / Mus musculus GTPase activating RANGAP domain-like 3 (Garnl3...ENSGALG0000000084727
RALGAPA1 / ral GTPase-activating protein subunit alpha-1 isoform 3 / Q6GYQ0* / Q6GYP7* / Ral GTPase activating protein, alpha subunit 1* / Ral GTPase activating protein catalytic alpha subunit 1*ENSGALG0000001008813
TSC2 / TSC complex subunit 2 / P49815* / tuberous sclerosis 2*ENSGALG0000000564611
A3KGS3* / Q2PPJ7* / RALGAPA2* / Ral GTPase-activating protein subunit alpha-2 * / Ral GTPase activating protein catalytic alpha subunit 2*ENSGALG000000447304
A3KGS3* / Q2PPJ7* / RALGAPA2* / Ral GTPase-activating protein subunit alpha-2 * / Ral GTPase activating protein catalytic alpha subunit 2*ENSGALG000000329640


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain
 IPR003109  GoLoco motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0030695 GTPase regulator activity IEA


Pathways (from Reactome)
Pathway description
Rap1 signalling
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002555 RET / ret proto-oncogene / P07949* / P35546* / Proto-onco tyrosine-protein kinase receptor Ret Soluble RET kinase fragment Extracellular cell-membrane anchored RET cadherin 120 kDa fragment*  / complex / reaction
 ENSGALG00000009173 GFRA1 / O13156 / GDNF family receptor alpha-1 / P56159* / P97785*  / complex / reaction
 ENSGALG00000003716 GDNF / glial cell derived neurotrophic factor / P39905* / P48540* / Mus musculus glial cell line derived neurotrophic factor (Gdnf), transcript variant 3, mRNA.*  / reaction / complex
 ENSGALG00000007620 GFRA3 / GDNF family receptor alpha 3 / O35118* / O60609*  / reaction / complex
 ENSGALG00000021647 NRTN / neurturin / P97463* / Q99748*  / reaction / complex
 ENSGALG00000009927 RAP1B / Q5ZHX1 / Ras-related protein Rap-1b / Q99JI6* / P61224* / RAS related protein 1b* / RAP1B, member of RAS oncogene family*  / reaction
 ENSGALG00000001476 RAP1A / RAP1A, member of RAS oncogene family / P62834* / P62835* / RAS-related protein 1a*  / reaction






 

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