ENSDARG00000053272


Danio rerio

Features
Gene ID: ENSDARG00000053272
  
Biological name :si:dkey-166d12.2
  
Synonyms : si:dkey-166d12.2
  
Possible biological names infered from orthology : A2ALS5 / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA. / P47736 / RAP1GAP / RAP1 GTPase activating protein
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 47869397
Gene end: 47953829
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000069758
Ensembl peptide - ENSDARP00000129011
NCBI entrez gene - 100538309     See in Manteia.
RefSeq - XM_009302683
swissprot - F1Q8E0
ZFIN ID - ZDB-GENE-131119-39
Ensembl - ENSDARG00000053272
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAP1GAP1ENSGALG00000014701Gallus gallus
 P47736ENSG00000076864Homo sapiens
 A2ALS5ENSMUSG00000041351Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rap1gap / RAP1 GTPase activating protein / A2ALS5* / P47736* / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA.*ENSDARG0000005655474
rap1gap2b / RAP1 GTPase activating protein 2b / Q5SVL6* / Q684P5* / RAP1GAP2* / RAP1 GTPase activating protein 2*ENSDARG0000007422244
rap1gap2a / RAP1 GTPase activating protein 2a / Q5SVL6* / Q684P5* / RAP1GAP2* / RAP1 GTPase activating protein 2*ENSDARG0000006155137
si:ch1073-90m23.1ENSDARG0000009157332
sipa1l1 / signal-induced proliferation-associated 1 like 1 / O43166* / Q8C0T5* / Signal-induced proliferation-associated 1-like protein 1 *ENSDARG0000002013428
sipa1l2 / signal-induced proliferation-associated 1 like 2 / Q80TE4* / Q9P2F8* / Mus musculus signal-induced proliferation-associated 1 like 2 (Sipa1l2), transcript variant 2, mRNA.*ENSDARG0000006164026
sipa1l3 / signal-induced proliferation-associated 1 like 3 / G3X9J0* / O60292*ENSDARG0000006169926
A5PF44 / si:ch211-182d3.1 / GARNL3* / Q5VVW2* / GTPase activating Rap/RanGAP domain like 3*ENSDARG0000006063122
zmp:0000001168 / SIPA1* / Q96FS4* / signal-induced proliferation-associated 1*ENSDARG0000007669722
ralgapa2 / Ral GTPase activating protein, alpha subunit 2 (catalytic) / Q2PPJ7* / A3KGS3* / Ral GTPase-activating protein subunit alpha-2 * / Ral GTPase activating protein catalytic alpha subunit 2*ENSDARG0000000586112
ralgapa1 / Ral GTPase activating protein, alpha subunit 1 (catalytic) / Q6GYQ0* / Q6GYP7* / Ral GTPase activating protein, alpha subunit 1* / Ral GTPase activating protein catalytic alpha subunit 1*ENSDARG0000007688912
tsc2 / TSC complex subunit 2ENSDARG000001031257
CABZ01067150.1ENSDARG000001161221


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 molecular_functionGO:0005096 GTPase activator activity IEA


Pathways (from Reactome)
Pathway description
Rap1 signalling
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042723 gfra2a / GDNF family receptor alpha 2a / GFRA2* / O00451* / O08842* / GDNF family receptor alpha 2*  / complex / reaction
 ENSDARG00000044015 gfra2b / GDNF family receptor alpha 2b / GFRA2* / O00451* / O08842* / GDNF family receptor alpha 2*  / complex / reaction
 ENSDARG00000055305 ret / ret proto-oncogene receptor tyrosine kinase / P07949* / P35546* / ret proto-oncogene* / Proto-onco tyrosine-protein kinase receptor Ret Soluble RET kinase fragment Extracellular cell-...  / complex / reaction
 ENSDARG00000008867 rap1b / Q6TEN1 / RAP1B, member of RAS oncogene family / Q99JI6* / P61224* / RAS related protein 1b*  / reaction
 ENSDARG00000012553 rap1aa / RAP1A, member of RAS oncogene family a / RAP1B* / Q99JI6* / P61224* / RAS related protein 1b* / RAP1B, member of RAS oncogene family*  / reaction
 ENSDARG00000087346 rap1ab / RAP1A, member of RAS oncogene family b / RAP1B* / Q99JI6* / P61224* / RAS related protein 1b* / RAP1B, member of RAS oncogene family*  / reaction
 ENSDARG00000079849 nrtn / neurturin / P97463* / Q99748*  / complex / reaction
 ENSDARG00000074582 gfra4b / GDNF family receptor alpha 4b / GFRA4* / Q9GZZ7* / Q9JJT2* / GDNF family receptor alpha 4*  / complex / reaction
 ENSDARG00000087704 gfra3 / GDNF family receptor alpha 3 / O35118* / O60609*  / reaction / complex
 ENSDARG00000039959 gdnfa / glial cell derived neurotrophic factor a / GDNF* / P39905* / P48540* / glial cell derived neurotrophic factor* / Mus musculus glial cell line derived neurotrophic factor (Gdnf), tra...  / reaction / complex






 

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