ENSGALG00000007620


Gallus gallus

Features
Gene ID: ENSGALG00000007620
  
Biological name :GFRA3
  
Synonyms : GDNF family receptor alpha 3 / GFRA3
  
Possible biological names infered from orthology : O35118 / O60609
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 18211398
Gene end: 18219351
  
Corresponding Affymetrix probe sets: GgaAffx.22298.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012311
NCBI entrez gene - 416353     See in Manteia.
RefSeq - XM_015294043
swissprot - F1NKR0
Ensembl - ENSGALG00000007620
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gfra3ENSDARG00000087704Danio rerio
 GFRA3ENSG00000146013Homo sapiens
 Gfra3ENSMUSG00000024366Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GFRA1 / O13156 / GDNF family receptor alpha-1 / P56159* / P97785*ENSGALG0000000917335
GFRA4 / GDNF family receptor alpha-4 precursor / Q9GZZ7* / Q9JJT2* / GDNF family receptor alpha 4*ENSGALG0000003658935
GFRA2 / GDNF family receptor alpha-2 precursor / O00451* / O08842* / GDNF family receptor alpha 2*ENSGALG0000003285634


Protein motifs (from Interpro)
Interpro ID Name
 IPR003438  Glial cell line-derived neurotrophic factor receptor
 IPR016017  GDNF/GAS1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0048485 sympathetic nervous system development IEA
 biological_processGO:0048666 neuron development IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 molecular_functionGO:0008046 axon guidance receptor activity IEA


Pathways (from Reactome)
Pathway description
RAF/MAP kinase cascade
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004821 PTPN11 / Q90687 / Tyrosine-protein phosphatase non-receptor type 11 / P35235* / Q06124* / protein tyrosine phosphatase, non-receptor type 11*  / complex / reaction
 ENSGALG00000003716 GDNF / glial cell derived neurotrophic factor / P39905* / P48540* / Mus musculus glial cell line derived neurotrophic factor (Gdnf), transcript variant 3, mRNA.*  / complex / reaction
 ENSGALG00000003750 PLCG1 / phospholipase C gamma 1 / P19174* / Q62077* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 *  / complex / reaction
 ENSGALG00000003855 SRC / P00523 / Proto-oncogene tyrosine-protein kinase Src / P12931* / P05480* / Neuronal proto-onco tyrosine-protein kinase Src * / SRC proto-oncogene, non-receptor tyrosine kinase*  / complex / reaction
 ENSGALG00000021647 NRTN / neurturin / P97463* / Q99748*  / complex / reaction
 ENSGALG00000002583 PIK3CD / phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform / O00329* / O35904* / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta*  / complex
 ENSGALG00000002555 RET / ret proto-oncogene / P07949* / P35546* / Proto-onco tyrosine-protein kinase receptor Ret Soluble RET kinase fragment Extracellular cell-membrane anchored RET cadherin 120 kDa fragment*  / complex / reaction
 ENSGALG00000013100 GRB10 / growth factor receptor bound protein 10 / Q13322* / Q60760*  / complex / reaction
 ENSGALG00000009898 GAB1 / GRB2 associated binding protein 1 / Q13480* / Q9QYY0*  / complex
 ENSGALG00000007620 GFRA3 / GDNF family receptor alpha 3 / O35118* / O60609*  / complex / reaction
 ENSGALG00000008934 PIK3CA / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *  / complex
 ENSGALG00000005505 PIK3CB / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta / P42338* / Q8BTI9* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform *  / complex
 ENSGALG00000036500 GRB7 / growth factor receptor bound protein 7 / Q03160* / Q14451*  / complex / reaction
 ENSGALG00000014786 PIK3R1 / phosphoinositide-3-kinase regulatory subunit 1 / P26450* / P27986*  / complex
 ENSGALG00000008016 GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*  / reaction / complex
 ENSGALG00000010688 SHC3 / SHC adaptor protein 3 / Q61120* / Q92529* / src homology 2 domain-containing transforming protein C3*  / reaction / complex
 ENSGALG00000009966 FRS2 / fibroblast growth factor receptor substrate 2 / Q8C180* / Q8WU20*  / reaction / complex
 ENSGALG00000009173 GFRA1 / O13156 / GDNF family receptor alpha-1 / P56159* / P97785*  / reaction / complex
 ENSGALG00000014701 RAP1GAP1 / RAP1 GTPase activating protein / P47736* / A2ALS5* / RAP1GAP* / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA.*  / complex / reaction
 ENSGALG00000025950 PRKCA / protein kinase C alpha / P17252*  / reaction / complex
 ENSGALG00000039775 SHC1 / SHC adaptor protein 1 / P29353* / P98083* / SHC-transforming protein 1 *  / complex / reaction
 ENSGALG00000039450 SOS1 / SOS Ras/Rac guanine nucleotide exchange factor 1 / Q07889* / Q62245* / Son of sevenless homolog 1 *  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr