ENSMUSG00000038807


Mus musculus

Features
Gene ID: ENSMUSG00000038807
  
Biological name :Rap1gap2
  
Synonyms : Q5SVL6 / Rap1gap2 / Rap1 GTPase-activating protein 2
  
Possible biological names infered from orthology : Q684P5
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B5
Gene start: 74383356
Gene end: 74610915
  
Corresponding Affymetrix probe sets: 10388310 (MoGene1.0st)   1434754_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146728
Ensembl peptide - ENSMUSP00000040180
Ensembl peptide - ENSMUSP00000099580
Ensembl peptide - ENSMUSP00000117290
NCBI entrez gene - 380711     See in Manteia.
MGI - MGI:3028623
RefSeq - XM_011249098
RefSeq - XM_006533626
RefSeq - XM_006533627
RefSeq - XM_006533628
RefSeq - XM_006533629
RefSeq - XM_006533631
RefSeq - NM_001015046
RefSeq - XM_006533621
RefSeq - XM_006533622
RefSeq - XM_006533624
RefSeq Peptide - NP_001015046
swissprot - A0A171EBK8
swissprot - A0A140LI95
swissprot - Q5SUE5
swissprot - Q5SVL6
Ensembl - ENSMUSG00000038807
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rap1gap2aENSDARG00000061551Danio rerio
 rap1gap2bENSDARG00000074222Danio rerio
 RAP1GAP2ENSGALG00000033885Gallus gallus
 Q684P5ENSG00000132359Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2ALS5 / Rap1gap / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA. / P47736* / RAP1 GTPase activating protein*ENSMUSG0000004135148
G3X9J0 / Sipa1l3 / signal-induced proliferation-associated 1 like 3 / O60292*ENSMUSG0000003058332
Q8C0T5 / Sipa1l1 / Signal-induced proliferation-associated 1-like protein 1 / O43166* / signal induced proliferation associated 1 like 1*ENSMUSG0000004270031
Q80TE4 / Sipa1l2 / Mus musculus signal-induced proliferation-associated 1 like 2 (Sipa1l2), transcript variant 2, mRNA. / Q9P2F8* / signal induced proliferation associated 1 like 2*ENSMUSG0000000199530
Sipa1 / signal-induced proliferation-associated 1 / Q96FS4*ENSMUSG0000005691726
Garnl3 / Q3V0G7 / Mus musculus GTPase activating RANGAP domain-like 3 (Garnl3), transcript variant 2, mRNA. / Q5VVW2* / GTPase activating Rap/RanGAP domain like 3*ENSMUSG0000003886024
A3KGS3 / Ralgapa2 / Ral GTPase-activating protein subunit alpha-2 / Q2PPJ7* / Ral GTPase activating protein catalytic alpha subunit 2*ENSMUSG0000003711014
Q6GYP7 / Ralgapa1 / Ral GTPase activating protein, alpha subunit 1 / Q6GYQ0* / Ral GTPase activating protein catalytic alpha subunit 1*ENSMUSG0000002102714
Tsc2 / tuberous sclerosis 2 / P49815* / TSC complex subunit 2*ENSMUSG0000000249611


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain
 IPR035974  Rap/Ran-GAP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008361 regulation of cell size IEA
 biological_processGO:0010977 negative regulation of neuron projection development IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0043005 neuron projection IDA
 molecular_functionGO:0005096 GTPase activator activity IEA


Pathways (from Reactome)
Pathway description
Rap1 signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005469 P05132 / Prkaca / protein kinase, cAMP dependent, catalytic, alpha / P17612* / protein kinase cAMP-activated catalytic subunit alpha*  / reaction
 ENSMUSG00000005034 P68181 / Prkacb / protein kinase, cAMP dependent, catalytic, beta / P22694* / protein kinase cAMP-activated catalytic subunit beta*  / reaction
 ENSMUSG00000018326 Ywhab / Q9CQV8 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta*  / reaction / complex
 ENSMUSG00000068798 Rap1a / P62835 / RAS-related protein 1a / P62834* / RAP1A, member of RAS oncogene family*  / reaction
 ENSMUSG00000052681 Rap1b / Q99JI6 / RAS related protein 1b / P61224* / RAP1B, member of RAS oncogene family*  / reaction
 ENSMUSG00000052920 Prkg1 / P0C605 / protein kinase, cGMP-dependent, type I / Q13976*  / reaction






 

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