ENSMUSG00000001995


Mus musculus

Features
Gene ID: ENSMUSG00000001995
  
Biological name :Sipa1l2
  
Synonyms : Mus musculus signal-induced proliferation-associated 1 like 2 (Sipa1l2), transcript variant 2, mRNA. / Q80TE4 / Sipa1l2
  
Possible biological names infered from orthology : Q9P2F8 / signal induced proliferation associated 1 like 2
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: E2
Gene start: 125418063
Gene end: 125569808
  
Corresponding Affymetrix probe sets: 10582719 (MoGene1.0st)   1434261_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000104405
Ensembl peptide - ENSMUSP00000148536
Ensembl peptide - ENSMUSP00000148557
NCBI entrez gene - 244668     See in Manteia.
MGI - MGI:2676970
RefSeq - XM_011248389
RefSeq - NM_001081337
RefSeq - NM_001357372
RefSeq - XM_006531024
RefSeq - XM_006531025
RefSeq Peptide - NP_001074806
RefSeq Peptide - NP_001344301
swissprot - Q80TE4
swissprot - A0A1D5RLY9
Ensembl - ENSMUSG00000001995
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sipa1l2ENSDARG00000061640Danio rerio
 SIPA1L2ENSGALG00000037506Gallus gallus
 Q9P2F8ENSG00000116991Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8C0T5 / Sipa1l1 / Signal-induced proliferation-associated 1-like protein 1 / O43166* / signal induced proliferation associated 1 like 1*ENSMUSG0000004270053
G3X9J0 / Sipa1l3 / signal-induced proliferation-associated 1 like 3 / O60292*ENSMUSG0000003058347
Sipa1 / signal-induced proliferation-associated 1 / Q96FS4*ENSMUSG0000005691726
Garnl3 / Q3V0G7 / Mus musculus GTPase activating RANGAP domain-like 3 (Garnl3), transcript variant 2, mRNA. / Q5VVW2* / GTPase activating Rap/RanGAP domain like 3*ENSMUSG0000003886014
Q5SVL6 / Rap1gap2 / Rap1 GTPase-activating protein 2 / Q684P5*ENSMUSG0000003880712
Q6GYP7 / Ralgapa1 / Ral GTPase activating protein, alpha subunit 1 / Q6GYQ0* / Ral GTPase activating protein catalytic alpha subunit 1*ENSMUSG0000002102712
A2ALS5 / Rap1gap / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA. / P47736* / RAP1 GTPase activating protein*ENSMUSG0000004135112
A3KGS3 / Ralgapa2 / Ral GTPase-activating protein subunit alpha-2 / Q2PPJ7* / Ral GTPase activating protein catalytic alpha subunit 2*ENSMUSG0000003711011
Tsc2 / tuberous sclerosis 2 / P49815* / TSC complex subunit 2*ENSMUSG000000024969


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain
 IPR001478  PDZ domain
 IPR021818  Signal-induced proliferation-associated 1-like protein, C-terminal
 IPR031203  Signal-induced proliferation-associated 1-like protein 2
 IPR035974  Rap/Ran-GAP superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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