ENSMUSG00000042700


Mus musculus

Features
Gene ID: ENSMUSG00000042700
  
Biological name :Sipa1l1
  
Synonyms : Q8C0T5 / Signal-induced proliferation-associated 1-like protein 1 / Sipa1l1
  
Possible biological names infered from orthology : O43166 / signal induced proliferation associated 1 like 1
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: D1
Gene start: 82169320
Gene end: 82451786
  
Corresponding Affymetrix probe sets: 10397002 (MoGene1.0st)   1434222_at (Mouse Genome 430 2.0 Array)   1439755_at (Mouse Genome 430 2.0 Array)   1440119_at (Mouse Genome 430 2.0 Array)   1440647_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152681
Ensembl peptide - ENSMUSP00000152356
Ensembl peptide - ENSMUSP00000152485
Ensembl peptide - ENSMUSP00000061014
Ensembl peptide - ENSMUSP00000131030
Ensembl peptide - ENSMUSP00000152212
NCBI entrez gene - 217692     See in Manteia.
MGI - MGI:2443679
RefSeq - XM_017315029
RefSeq - NM_001167983
RefSeq - NM_172579
RefSeq - XM_011244069
RefSeq - XM_017315025
RefSeq - XM_017315026
RefSeq - XM_017315027
RefSeq - XM_017315028
RefSeq - XM_006515684
RefSeq - XM_011244060
RefSeq - XM_011244061
RefSeq - XM_011244062
RefSeq - XM_011244063
RefSeq - XM_011244064
RefSeq - XM_011244066
RefSeq - XM_011244067
RefSeq - XM_011244068
RefSeq Peptide - NP_001161455
RefSeq Peptide - NP_766167
swissprot - Q4VBF8
swissprot - Q8C0T5
swissprot - A0A1Y7VJM1
Ensembl - ENSMUSG00000042700
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sipa1l1ENSDARG00000020134Danio rerio
 SIPA1L1ENSGALG00000009381Gallus gallus
 O43166ENSG00000197555Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80TE4 / Sipa1l2 / Mus musculus signal-induced proliferation-associated 1 like 2 (Sipa1l2), transcript variant 2, mRNA. / Q9P2F8* / signal induced proliferation associated 1 like 2*ENSMUSG0000000199551
G3X9J0 / Sipa1l3 / signal-induced proliferation-associated 1 like 3 / O60292*ENSMUSG0000003058348
Sipa1 / signal-induced proliferation-associated 1 / Q96FS4*ENSMUSG0000005691725
Garnl3 / Q3V0G7 / Mus musculus GTPase activating RANGAP domain-like 3 (Garnl3), transcript variant 2, mRNA. / Q5VVW2* / GTPase activating Rap/RanGAP domain like 3*ENSMUSG0000003886013
Q5SVL6 / Rap1gap2 / Rap1 GTPase-activating protein 2 / Q684P5*ENSMUSG0000003880712
Q6GYP7 / Ralgapa1 / Ral GTPase activating protein, alpha subunit 1 / Q6GYQ0* / Ral GTPase activating protein catalytic alpha subunit 1*ENSMUSG0000002102712
A3KGS3 / Ralgapa2 / Ral GTPase-activating protein subunit alpha-2 / Q2PPJ7* / Ral GTPase activating protein catalytic alpha subunit 2*ENSMUSG0000003711012
A2ALS5 / Rap1gap / Mus musculus Rap1 GTPase-activating protein (Rap1gap), transcript variant 5, mRNA. / P47736* / RAP1 GTPase activating protein*ENSMUSG0000004135111
Tsc2 / tuberous sclerosis 2 / P49815* / TSC complex subunit 2*ENSMUSG000000024969


Protein motifs (from Interpro)
Interpro ID Name
 IPR000331  Rap GTPase activating protein domain
 IPR001478  PDZ domain
 IPR011993  PH-like domain superfamily
 IPR021818  Signal-induced proliferation-associated 1-like protein, C-terminal
 IPR030770  Signal-induced proliferation-associated 1-like protein 1
 IPR035974  Rap/Ran-GAP superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031532 actin cytoskeleton reorganization ISS
 biological_processGO:0043087 regulation of GTPase activity IMP
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IMP
 biological_processGO:0048167 regulation of synaptic plasticity ISS
 biological_processGO:0048814 regulation of dendrite morphogenesis IEA
 biological_processGO:0050770 regulation of axonogenesis IDA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 biological_processGO:0061001 regulation of dendritic spine morphogenesis ISS
 biological_processGO:0090630 activation of GTPase activity ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043197 dendritic spine ISS
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046875 ephrin receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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