ENSMUSG00000005469


Mus musculus

Features
Gene ID: ENSMUSG00000005469
  
Biological name :Prkaca
  
Synonyms : P05132 / Prkaca / protein kinase, cAMP dependent, catalytic, alpha
  
Possible biological names infered from orthology : P17612 / protein kinase cAMP-activated catalytic subunit alpha
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C2
Gene start: 83972993
Gene end: 83996443
  
Corresponding Affymetrix probe sets: 10573266 (MoGene1.0st)   1447720_x_at (Mouse Genome 430 2.0 Array)   1450519_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000005606
Ensembl peptide - ENSMUSP00000147256
NCBI entrez gene - 18747     See in Manteia.
MGI - MGI:97592
RefSeq - NM_001277898
RefSeq - NM_008854
RefSeq Peptide - NP_001264827
RefSeq Peptide - NP_032880
swissprot - P05132
Ensembl - ENSMUSG00000005469
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P17612ENSG00000072062Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P68181 / Prkacb / protein kinase, cAMP dependent, catalytic, beta / P22694* / protein kinase cAMP-activated catalytic subunit beta*ENSMUSG0000000503489
Prkx / Q922R0 / cAMP-dependent protein kinase catalytic subunit PRKX / P51817* / protein kinase, X-linked*ENSMUSG0000003572548
Prkg1 / P0C605 / protein kinase, cGMP-dependent, type I / Q13976*ENSMUSG0000005292043
Prkg2 / protein kinase, cGMP-dependent, type II / Q13237*ENSMUSG0000002933442


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001707 mesoderm formation IGI
 biological_processGO:0001843 neural tube closure IGI
 biological_processGO:0006397 mRNA processing ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IMP
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0034605 cellular response to heat ISS
 biological_processGO:0045667 regulation of osteoblast differentiation ISO
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0046827 positive regulation of protein export from nucleus IMP
 biological_processGO:0048240 sperm capacitation IDA
 biological_processGO:0050804 modulation of chemical synaptic transmission IMP
 biological_processGO:0061136 regulation of proteasomal protein catabolic process ISO
 biological_processGO:0070613 regulation of protein processing IGI
 biological_processGO:0071158 positive regulation of cell cycle arrest IDA
 biological_processGO:0071333 cellular response to glucose stimulus ISO
 biological_processGO:0071374 cellular response to parathyroid hormone stimulus IMP
 biological_processGO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning IGI
 biological_processGO:2000810 regulation of bicellular tight junction assembly ISO
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005930 axoneme ISO
 cellular_componentGO:0005952 cAMP-dependent protein kinase complex IMP
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031514 motile cilium IEA
 cellular_componentGO:0031588 nucleotide-activated protein kinase complex ISO
 cellular_componentGO:0031594 neuromuscular junction IDA
 cellular_componentGO:0036126 sperm flagellum IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine IDA
 cellular_componentGO:0044853 plasma membrane raft ISO
 cellular_componentGO:0045171 intercellular bridge ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 cellular_componentGO:0097225 sperm midpiece ISO
 cellular_componentGO:0097546 ciliary base IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity IMP
 molecular_functionGO:0004691 cAMP-dependent protein kinase activity TAS
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IMP
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0030145 manganese ion binding IMP
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding IPI


Pathways (from Reactome)
Pathway description
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Rap1 signalling
Vasopressin regulates renal water homeostasis via Aquaporins
VEGFA-VEGFR2 Pathway
CREB phosphorylation through the activation of Adenylate Cyclase
Interleukin-3, Interleukin-5 and GM-CSF signaling
Ion homeostasis
GLI3 is processed to GLI3R by the proteasome
Hedgehog off state
Anchoring of the basal body to the plasma membrane
CD209 (DC-SIGN) signaling
MAPK6/MAPK4 signaling
RET signaling
AURKA Activation by TPX2
HDL assembly
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Prkacatm2Gsm/Prkacatm2Gsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000961 abnormal dorsal root ganglia morphology "malformed group of nerve cell bodies of each segmental nerve projecting from the spinal cord " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:60159]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000962 disorganized dorsal root ganglia "loss of segmentation pattern of DRGs; loss of regular spacing " [J:62022, J:62023]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001787 pericardial edema "accumulation of watery fluid in the pericardial sac of the heart" [J:52597]
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Allelic Composition: Prkar1atm1Gsm/Prkar1atm1Gsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

Allelic Composition: Prkacatm2Gsm/Prkacatm2Gsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Tpi1a-m6Neu/Tpi1+
Genetic Background: involves: 101/El * C3H/El

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

Allelic Composition: Prkacatm2Gsm/Prkacatm2Gsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0002948 abnormal neuronal specification "defects in the developmental patterning of neurons resulting in ectopic placement, decreased numbers or absence of mature neurons" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:87948]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002963 decreased protein excretion "less than the normal amount of serum proteins voided by the kidneys" [RGD:Rat Genome Database submission]
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Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

 MP:0003054 spina bifida "common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003059 decreased insulin secretion "less than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003789 osteosarcoma "malignant neoplasm derived from bone" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0003797 abnormal compact bone morphology "structural anomaly of the outer layers of solid, hard bone that covers spongy bone; consists of parallel osteons containing mineral deposits and interstitial lamellae" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0004174 abnormal spine curvature "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004261 abnormal embryonic neuroepithelium morphology "any structural anomaly in the epithelial cell layer that lines the neural tube and develops into the nervous system and into the neural crest cells" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition", MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004599 abnormal vertebral arch morphology "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004703 abnormal vertebral column "any structural anomaly of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0005438 abnormal glycogen homeostasis "abnormal processing and or utilization of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0005439 decreased glycogen level "less than the normal concentration of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
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Allelic Composition: Prkacatm3Gsm/Prkacatm3Gsm,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0009346 decreased cancellous bone thickness "thinner than normal bone with a lattice-like or spongy structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0010079 osteochondroma "a benign cartilagenous neoplasm that consists of a pedicle of normal bone capped by a region of proliferating cartilage cells; most often associated with one or more of the long bones" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0010280 increased skeletal tumor incidence "greater than the expected number of neoplasms in the skeletal tissue, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0010971 abnormal periosteum morphology "any structural anomaly of the thick fibrous membrane that closely invests the entire surface of a bone except the articular cartilage at synovial joints" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
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Allelic Composition: Prkacatm1Gsm/Prkacatm1Gsm,Prkacbtm1Gsm/Prkacb+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0012505 increased neural tube apoptosis "increase in the number of cells of the neural tube undergoing programmed cell death" [MGI:anna]
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Allelic Composition: Vegfatm4Pec/Vegfatm4Pec
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002997 P31324 / Prkar2b / protein kinase, cAMP dependent regulatory, type II beta / P31323* / protein kinase cAMP-dependent type II regulatory subunit beta*  / complex
 ENSMUSG00000035458 Tnni3 / P48787 / troponin I, cardiac 3 / P19429* / troponin I3, cardiac type*  / reaction
 ENSMUSG00000068758 Il3ra / P26952 / Interleukin-3 receptor subunit alpha / P26951*  / reaction
 ENSMUSG00000024789 Jak2 / Janus kinase 2 / O60674*  / reaction
 ENSMUSG00000024927 Rela / Q04207 / v-rel reticuloendotheliosis viral oncogene homolog A (avian) / Q04206* / RELA proto-oncogene, NF-kB subunit*  / reaction
 ENSMUSG00000005034 P68181 / Prkacb / protein kinase, cAMP dependent, catalytic, beta / P22694* / protein kinase cAMP-activated catalytic subunit beta*  / complex
 ENSMUSG00000038807 Q5SVL6 / Rap1gap2 / Rap1 GTPase-activating protein 2 / Q684P5*  / reaction
 ENSMUSG00000059326 Csf2ra / Q00941 / Granulocyte-macrophage colony-stimulating factor receptor subunit alpha / P15509* / colony stimulating factor 2 receptor alpha subunit*  / reaction
 ENSMUSG00000018916 Csf2 / P01587 / Granulocyte-macrophage colony-stimulating factor / P04141* / colony stimulating factor 2*  / reaction
 ENSMUSG00000023013 Aqp2 / P56402 / Aquaporin-2 / P41181*  / reaction
 ENSMUSG00000071714 P26954 / Csf2rb2 / Interleukin-3 receptor class 2 subunit beta / CSF2RB* / P32927* / colony stimulating factor 2 receptor beta common subunit*  / reaction
 ENSMUSG00000071713 Csf2rb / P26955 / Mus musculus colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (Csf2rb), transcript variant 1, mRNA. / P32927* / colony stimulating factor ...  / reaction
 ENSMUSG00000021318 Gli3 / Q61602 / Transcriptional activator GLI3 Transcriptional repressor GLI3R / P10071* / GLI family zinc finger 3*  / reaction
 ENSMUSG00000030546 Plin1 / Q8CGN5 / Perilipin-1 / O60240*  / reaction
 ENSMUSG00000029454 O54992 / Mapkapk5 / MAP kinase-activated protein kinase 5 / Q8IW41* / mitogen-activated protein kinase-activated protein kinase 5*  / reaction
 ENSMUSG00000048402 Gli2 / Q0VGT2 / Zinc finger protein GLI2 / P10070* / GLI family zinc finger 2*  / reaction
 ENSMUSG00000005364 Il5ra / P21183 / Interleukin-5 receptor subunit alpha / Q01344*  / reaction
 ENSMUSG00000038583 Pln / P61014 / Cardiac phospholamban / P26678* / phospholamban*  / reaction
 ENSMUSG00000028163 Nfkb1 / P25799 / Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p50 subunit / P19838* / nuclear factor kappa B subunit 1*  / reaction
 ENSMUSG00000025231 Sufu / Q9Z0P7 / SUFU negative regulator of hedgehog signaling / Q9UMX1*  / reaction
 ENSMUSG00000015243 Abca1 / P41233 / ATP-binding cassette, sub-family A (ABC1), member 1 / O95477* / ATP binding cassette subfamily A member 1*  / reaction
 ENSMUSG00000005469 P05132 / Prkaca / protein kinase, cAMP dependent, catalytic, alpha / P17612* / protein kinase cAMP-activated catalytic subunit alpha*  / complex
 ENSMUSG00000036117 Il5 / P04401 / Interleukin-5 / P05113*  / reaction
 ENSMUSG00000021057 Akap5 / D3YVF0 / A-kinase anchor protein 5 / P24588* / A-kinase anchoring protein 5*  / reaction / complex
 ENSMUSG00000005373 Mlxipl / Q99MZ3 / Carbohydrate-responsive element-binding protein / Q9NP71* / MLX interacting protein like*  / reaction
 ENSMUSG00000018428 Akap1 / O08715 / A-kinase anchor protein 1, mitochondrial / Q92667* / A-kinase anchoring protein 1*  / reaction / complex
 ENSMUSG00000025855 P12849 / Prkar1b / protein kinase, cAMP dependent regulatory, type I beta / P31321* / protein kinase cAMP-dependent type I regulatory subunit beta*  / complex
 ENSMUSG00000032601 Prkar2a / protein kinase, cAMP dependent regulatory, type II alpha / P13861* / protein kinase cAMP-dependent type II regulatory subunit alpha*  / complex
 ENSMUSG00000020612 Q9DBC7 / Prkar1a / protein kinase, cAMP dependent regulatory, type I, alpha / P10644* / protein kinase cAMP-dependent type I regulatory subunit alpha*  / complex
 ENSMUSG00000047804 Akap10 / O88845 / A-kinase anchor protein 10, mitochondrial / O43572* / A-kinase anchoring protein 10*  / reaction / complex






 

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