Manteia

ENSMUSG00000018428

Mus musculus

Features

Gene ID:	ENSMUSG00000018428

Biological name :	Akap1

Synonyms :	Akap1 / A-kinase anchor protein 1, mitochondrial / O08715

Possible biological names infered from orthology :	A-kinase anchoring protein 1 / Q92667

Species:	Mus musculus

Chr. number:	11
Strand:	-1
Band:	C
Gene start:	88830792
Gene end:	88864586

Corresponding Affymetrix probe sets:	10389701 (MoGene1.0st) 1418279_a_at (Mouse Genome 430 2.0 Array) 1449019_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000103537 Ensembl peptide - ENSMUSP00000123018 Ensembl peptide - ENSMUSP00000018572 Ensembl peptide - ENSMUSP00000103536 Ensembl peptide - ENSMUSP00000122295 NCBI entrez gene - 11640 See in Manteia. MGI - MGI:104729 RefSeq - NM_001042541 RefSeq - NM_009648 RefSeq Peptide - NP_001036006 RefSeq Peptide - NP_033778 swissprot - O08715 swissprot - F6V317 Ensembl - ENSMUSG00000018428

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR002999	Tudor domain
IPR004087	K Homology domain
IPR004088	K Homology domain, type 1
IPR033104	A-kinase anchor protein 1, mitochondrial
IPR035437	SNase-like, OB-fold superfamily
IPR036612	K Homology domain, type 1 superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0010738	regulation of protein kinase A signaling	IEA
cellular_component	GO:0005739	mitochondrion	ISO
cellular_component	GO:0005741	mitochondrial outer membrane	TAS
cellular_component	GO:0005783	endoplasmic reticulum	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0003676	nucleic acid binding	IEA
molecular_function	GO:0003723	RNA binding	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0034237	protein kinase A regulatory subunit binding	ISO

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001923	reduced female fertility	"reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Ppp1r1b^tm2Pggd/Ppp1r1b^tm2Pggd Genetic Background: involves: 129 * C57BL/6
MP:0001935	reduced litter size	"fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ppp1r1b^tm2Pggd/Ppp1r1b^tm2Pggd Genetic Background: involves: 129 * C57BL/6
MP:0005168	abnormal female meiosis	"malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ppp1r1b^tm2Pggd/Ppp1r1b^tm2Pggd Genetic Background: involves: 129 * C57BL/6

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000005034	P68181 / Prkacb / protein kinase, cAMP dependent, catalytic, beta / P22694* / protein kinase cAMP-activated catalytic subunit beta*	/ reaction / complex
ENSMUSG00000025855	P12849 / Prkar1b / protein kinase, cAMP dependent regulatory, type I beta / P31321* / protein kinase cAMP-dependent type I regulatory subunit beta*	/ reaction / complex
ENSMUSG00000020612	Q9DBC7 / Prkar1a / protein kinase, cAMP dependent regulatory, type I, alpha / P10644* / protein kinase cAMP-dependent type I regulatory subunit alpha*	/ reaction / complex
ENSMUSG00000032601	Prkar2a / protein kinase, cAMP dependent regulatory, type II alpha / P13861* / protein kinase cAMP-dependent type II regulatory subunit alpha*	/ complex / reaction
ENSMUSG00000005469	P05132 / Prkaca / protein kinase, cAMP dependent, catalytic, alpha / P17612* / protein kinase cAMP-activated catalytic subunit alpha*	/ reaction / complex
ENSMUSG00000002997	P31324 / Prkar2b / protein kinase, cAMP dependent regulatory, type II beta / P31323* / protein kinase cAMP-dependent type II regulatory subunit beta*	/ reaction / complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr