ENSG00000121057


Homo sapiens

Features
Gene ID: ENSG00000121057
  
Biological name :AKAP1
  
Synonyms : AKAP1 / A-kinase anchoring protein 1 / Q92667
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q22
Gene start: 57085092
Gene end: 57121349
  
Corresponding Affymetrix probe sets: 201674_s_at (Human Genome U133 Plus 2.0 Array)   201675_at (Human Genome U133 Plus 2.0 Array)   210625_s_at (Human Genome U133 Plus 2.0 Array)   210626_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458378
Ensembl peptide - ENSP00000314075
Ensembl peptide - ENSP00000337736
Ensembl peptide - ENSP00000433212
Ensembl peptide - ENSP00000443139
Ensembl peptide - ENSP00000458164
Ensembl peptide - ENSP00000458370
Ensembl peptide - ENSP00000458982
Ensembl peptide - ENSP00000459521
Ensembl peptide - ENSP00000459808
Ensembl peptide - ENSP00000459895
Ensembl peptide - ENSP00000459968
Ensembl peptide - ENSP00000460209
Ensembl peptide - ENSP00000460514
Ensembl peptide - ENSP00000460557
Ensembl peptide - ENSP00000460762
Ensembl peptide - ENSP00000461418
Ensembl peptide - ENSP00000461854
Ensembl peptide - ENSP00000478212
NCBI entrez gene - 8165     See in Manteia.
OMIM - 602449
RefSeq - XM_017025190
RefSeq - XM_017025191
RefSeq - XM_005257709
RefSeq - XM_017025189
RefSeq - NM_001242902
RefSeq - NM_001242903
RefSeq - NM_003488
RefSeq - XM_005257707
RefSeq Peptide - NP_001229832
RefSeq Peptide - NP_001229831
RefSeq Peptide - NP_003479
swissprot - I3L3K1
swissprot - I3L3L9
swissprot - I3L3V6
swissprot - I3NI36
swissprot - I3L0K6
swissprot - Q92667
swissprot - I3L0W0
swissprot - I3L2A2
swissprot - I3L0V5
swissprot - A0A140VK05
swissprot - A0A0G2JLF7
swissprot - I3L2N7
swissprot - I3L364
Ensembl - ENSG00000121057
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akap1bENSDARG00000006062Danio rerio
 AKAP1ENSGALG00000005575Gallus gallus
 Akap1ENSMUSG00000018428Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002999  Tudor domain
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR018459  RII binding domain
 IPR033104  A-kinase anchor protein 1, mitochondrial
 IPR035437  SNase-like, OB-fold superfamily
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0010738 regulation of protein kinase A signaling IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding IPI


Pathways (from Reactome)
Pathway description
Mitochondrial calcium ion transport
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100678 P57103 / SLC8A3 / solute carrier family 8 member A3  / complex
 ENSG00000165059 P22612 / PRKACG / protein kinase cAMP-activated catalytic subunit gamma  / reaction / complex
 ENSG00000114302 P13861 / PRKAR2A / protein kinase cAMP-dependent type II regulatory subunit alpha  / reaction / complex
 ENSG00000005249 P31323 / PRKAR2B / protein kinase cAMP-dependent type II regulatory subunit beta  / reaction / complex
 ENSG00000108946 P10644 / PRKAR1A / protein kinase cAMP-dependent type I regulatory subunit alpha  / reaction / complex
 ENSG00000072062 P17612 / PRKACA / protein kinase cAMP-activated catalytic subunit alpha  / complex / reaction
 ENSG00000142875 P22694 / PRKACB / protein kinase cAMP-activated catalytic subunit beta  / complex / reaction
 ENSG00000188191 P31321 / PRKAR1B / protein kinase cAMP-dependent type I regulatory subunit beta  / complex / reaction






 

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