ENSMUSG00000021318


Mus musculus

Features
Gene ID: ENSMUSG00000021318
  
Biological name :Gli3
  
Synonyms : Gli3 / Q61602 / Transcriptional activator GLI3 Transcriptional repressor GLI3R
  
Possible biological names infered from orthology : GLI family zinc finger 3 / P10071
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A1
Gene start: 15463235
Gene end: 15730026
  
Corresponding Affymetrix probe sets: 10403727 (MoGene1.0st)   1450525_at (Mouse Genome 430 2.0 Array)   1455154_at (Mouse Genome 430 2.0 Array)   1456067_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115989
Ensembl peptide - ENSMUSP00000152092
Ensembl peptide - ENSMUSP00000106137
NCBI entrez gene - 14634     See in Manteia.
MGI - MGI:95729
RefSeq - NM_008130
RefSeq - XM_006516552
RefSeq Peptide - NP_032156
swissprot - B2RUG4
swissprot - Q3UMJ8
swissprot - Q61602
swissprot - A0A1Y7VKQ8
Ensembl - ENSMUSG00000021318
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLI3ENSGALG00000040266Gallus gallus
 GLI3ENSG00000106571Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gli2 / Q0VGT2 / Zinc finger protein GLI2 / P10070* / GLI family zinc finger 2*ENSMUSG0000004840244
Gli1 / P47806 / Zinc finger protein GLI1 / P08151* / GLI family zinc finger 1*ENSMUSG0000002540726
Glis3 / Q6XP49 / Zinc finger protein GLIS3 / Q8NEA6* / GLIS family zinc finger 3*ENSMUSG0000005294216
Glis1 / Q8K1M4 / Zinc finger protein GLIS1 / Q8NBF1* / GLIS family zinc finger 1*ENSMUSG0000003476213
Zic2 / zinc finger protein of the cerebellum 2 / O95409* / Zic family member 2*ENSMUSG0000006152410
Zic5 / zinc finger protein of the cerebellum 5 / Q96T25* / Zic family member 5*ENSMUSG0000004170310
Glis2 / Q8VDL9 / Zinc finger protein GLIS2 / Q9BZE0* / GLIS family zinc finger 2*ENSMUSG0000001430310
Zic3 / Q62521 / zinc finger protein of the cerebellum 3 / O60481* / Zic family member 3*ENSMUSG000000678609
Zic1 / P46684 / zinc finger protein of the cerebellum 1 / Q15915* / Zic family member 1*ENSMUSG000000323689
Zic4 / Q61467 / zinc finger protein of the cerebellum 4 / Q8N9L1* / Zic family member 4*ENSMUSG000000369727


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR032851  Transcription factor GLI3
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001656 metanephros development IGI
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IGI
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001822 kidney development IGI
 biological_processGO:0002052 positive regulation of neuroblast proliferation IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0007224 smoothened signaling pathway IGI
 biological_processGO:0007389 pattern specification process IGI
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0007442 hindgut morphogenesis IGI
 biological_processGO:0007507 heart development IGI
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0009954 proximal/distal pattern formation IMP
 biological_processGO:0010468 regulation of gene expression IGI
 biological_processGO:0016485 protein processing IDA
 biological_processGO:0021513 spinal cord dorsal/ventral patterning IGI
 biological_processGO:0021522 spinal cord motor neuron differentiation IGI
 biological_processGO:0021537 telencephalon development IMP
 biological_processGO:0021543 pallium development IMP
 biological_processGO:0021544 subpallium development IMP
 biological_processGO:0021631 optic nerve morphogenesis IMP
 biological_processGO:0021766 hippocampus development IMP
 biological_processGO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification IGI
 biological_processGO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification IGI
 biological_processGO:0021798 forebrain dorsal/ventral pattern formation IMP
 biological_processGO:0021801 cerebral cortex radial glia guided migration IMP
 biological_processGO:0021819 layer formation in cerebral cortex IMP
 biological_processGO:0021861 forebrain radial glial cell differentiation IMP
 biological_processGO:0021915 neural tube development IMP
 biological_processGO:0022018 lateral ganglionic eminence cell proliferation IMP
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0030324 lung development IMP
 biological_processGO:0030326 embryonic limb morphogenesis IMP
 biological_processGO:0030850 prostate gland development IEA
 biological_processGO:0030879 mammary gland development IMP
 biological_processGO:0030900 forebrain development IMP
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IMP
 biological_processGO:0033077 T cell differentiation in thymus IMP
 biological_processGO:0035108 limb morphogenesis ISO
 biological_processGO:0035295 tube development IGI
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042127 regulation of cell proliferation IGI
 biological_processGO:0042307 positive regulation of protein import into nucleus IGI
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IGI
 biological_processGO:0042733 embryonic digit morphogenesis IMP
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0043010 camera-type eye development IGI
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043586 tongue development IMP
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045060 negative thymic T cell selection IMP
 biological_processGO:0045595 regulation of cell differentiation IGI
 biological_processGO:0045596 negative regulation of cell differentiation IGI
 biological_processGO:0045665 negative regulation of neuron differentiation IMP
 biological_processGO:0045669 positive regulation of osteoblast differentiation IMP
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046638 positive regulation of alpha-beta T cell differentiation IMP
 biological_processGO:0046639 negative regulation of alpha-beta T cell differentiation IMP
 biological_processGO:0048557 embryonic digestive tract morphogenesis IMP
 biological_processGO:0048566 embryonic digestive tract development IMP
 biological_processGO:0048568 embryonic organ development IEA
 biological_processGO:0048589 developmental growth IMP
 biological_processGO:0048593 camera-type eye morphogenesis IMP
 biological_processGO:0048598 embryonic morphogenesis IMP
 biological_processGO:0048646 anatomical structure formation involved in morphogenesis IGI
 biological_processGO:0048663 neuron fate commitment IMP
 biological_processGO:0048704 embryonic skeletal system morphogenesis IGI
 biological_processGO:0048709 oligodendrocyte differentiation IGI
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IMP
 biological_processGO:0048839 inner ear development IGI
 biological_processGO:0048856 anatomical structure development IGI
 biological_processGO:0060021 roof of mouth development IMP
 biological_processGO:0060173 limb development IMP
 biological_processGO:0060364 frontal suture morphogenesis IMP
 biological_processGO:0060366 lambdoid suture morphogenesis IMP
 biological_processGO:0060367 sagittal suture morphogenesis IMP
 biological_processGO:0060594 mammary gland specification IGI
 biological_processGO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning IGI
 biological_processGO:0060840 artery development IGI
 biological_processGO:0060873 anterior semicircular canal development IMP
 biological_processGO:0060875 lateral semicircular canal development IMP
 biological_processGO:0061005 cell differentiation involved in kidney development IGI
 biological_processGO:0070242 thymocyte apoptotic process IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0097421 liver regeneration IEA
 biological_processGO:1903010 regulation of bone development IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005929 cilium ISO
 cellular_componentGO:0005930 axoneme IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016592 mediator complex IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IGI
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0035035 histone acetyltransferase binding ISO
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
GLI3 is processed to GLI3R by the proteasome
Hedgehog off state
Hedgehog on state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000023 abnormal ear distance/ position "anomaly in the space between or the placement of the outer ears " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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 MP:0000039 abnormal otic capsule morphology "malformation of the cartilage or bony capsule surrounding the inner ear mechanism" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0000065 abnormal bone marrow cavities "absence or abnormal size or shape of the medullary cavities of the bones" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+,Ihhtm1Amc/Ihhtm1Amc,Tg(Col2a1-cre)3Amc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

 MP:0000074 abnormal neurocranium morphology "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0000075 absent neurocranium "missing bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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 MP:0000106 abnormal basisphenoid bone morphology "malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0000116 abnormal tooth development "anomalous formation of the teeth" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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 MP:0000137 abnormal vertebrae morphology "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000149 abnormal scapula morphology "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15+
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3tm1.2Zllr/Gli3+,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000157 abnormal sternum morphology "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]
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Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: C3H/HeJ * CD-1

 MP:0000159 abnormal xiphoid process "malformed posterior tip of the sternum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:42932]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: C3H/HeJ * CD-1

 MP:0000164 abnormal cartilage development "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000288 abnormal pericardium morphology "malformation of the fibroserous membrane covering the heart and beginning of the great vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:54408]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0000373 belly spot "the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Mos1/Gli3+
Genetic Background: involves: BALB/cJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3+,Sox10tm1Weg/Sox10+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

Allelic Composition: Gli3Mos1/Gli3+,Sox10tm1Weg/Sox10+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J

 MP:0000413 polyphalangy "increased number of phalanges in any of the digits" [J:13069, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm1Alj/Gli2+,Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3Xt-J/Gli3+
Genetic Background: involves: 129/Sv * C3H/HeJ * C57BL/6

 MP:0000428 abnormal craniofacial morphology "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ccr8tm1Gma/Ccr8tm1Gma
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0000439 enlarged skull 
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000455 abnormal maxilla morphology "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0000460 mandible hypoplasia "arrested growth or atrophy of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

 MP:0000462 abnormal digestive system morphology "anomalous structure of the system dedicated to the mechanical, chemical, and enzymatic processing of food" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli3tm1Alj/Gli3tm1Alj,Nkx3-2tm1(cre)Wez/Nkx3-2+,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * 129X1/SvJ

 MP:0000474 abnormal foregut morphology "malformed cephalic portion of the primitive digestive tube of the embryo" [J:35802]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0000477 abnormal intestine morphology "malformation of the digestive tube passing from the stomach to the anus" [J:48968]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000495 abnormal colon morphology "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000547 short limbs "reduced average length of the extremities" [MGI:CLS, J:61509]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+,Ihhtm1Amc/Ihhtm1Amc,Tg(Col2a1-cre)3Amc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000550 abnormal forelimb morphology "malformation of the entire anterior extremities" [MGI:tc]
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Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000553 absent radius "missing the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54637]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000556 abnormal hindlimb morphology "malformation of the entire posterior extremities" [MGI:tc]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000561 adactyly "missing all digits; usually refered to as a congenital condition" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637]
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Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: C3H/HeJ

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Skitm1Cco/Ski+
Genetic Background: involves: C3H * C57BL/6

Allelic Composition: Gli3Pdn/Gli3+
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3Xt-J/Gli3+
Genetic Background: involves: C3H * CD-1

Allelic Composition: Gli2tm1Alj/Gli2+,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli1tm1Alj/Gli1tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/Sv * CD-1

Allelic Composition: Gli3Xt/Gli3Xt,Glis1tm1Mnks/Glis1tm1Mnks
Genetic Background: mixed

Allelic Composition: Gli3tm1Blnw/Gli3tm1Blnw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3tm1Blnw/Gli3Xt-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6

Allelic Composition: Gli3tm1Urt/Gli3+
Genetic Background: either: 129P2/OlaHsd-Gli3Tm1Urt or (involves: 129P2/OlaHsd * C57BL/6)

Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3Xt-J/Gli3+
Genetic Background: C3HeB/FeJ-Mc1rE-so Gli3Xt-J/J

Allelic Composition: Gas1tm2Fan/Gas1tm2Fan,Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129/Sv * C3H/HeJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129/Sv * C3H/HeJ * C57BL/6J

Allelic Composition: Gli3tm2Blnw/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt/Gli3+
Genetic Background: involves: 101/H * 129/Sv * C3H/HeH * C57BL/6

Allelic Composition: Gli3tm2Blnw/Gli3tm2Blnw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129/Sv * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3tm2Blnw/Gli3+,Shhtm1Chg/Shhtm1Chg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt-2H/Gli3Xt-2H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-5H/Gli3Xt-5H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-6H/Gli3Xt-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3Xt-J/Gli3+
Genetic Background: involves: C3H/HeJ * C57BL/6J * C57BL/6NHsd

Allelic Composition: Bmp4tm1Blh/Bmp4+,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S2/SvPas * C3H/HeJ * C57BL/6J * C57BL/6NHsd

Allelic Composition: Gli3add/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H * SJL

Allelic Composition: Gli3Xt-J/Gli3+,Tulp3hhkr/Tulp3+
Genetic Background: involves: C3H/HeH * C3H/HeJ * C57BL/6

Allelic Composition: Gli3Xt-J/Gli3+,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C3H/HeJ * C57BL/6

Allelic Composition: Gli2tm3.1(Gli1)Alj/Gli2+,Gli3Xt-J/Gli3+
Genetic Background: either: (involves: 129S6/SvEvTac * C3H/HeJ) or (involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ)

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: C3H/HeJ * CD-1

Allelic Composition: Gli3TgBR/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6J * CBA/H

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: C3H/HeJ * NMRI

Allelic Composition: Gli3tm1.2Zllr/Gli3Xt-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6J * NMRI

Allelic Composition: Gli3tm1.1Zllr/Gli3tm1.2Zllr,Hoxa13tm1.1(cre)Makm/Hoxa13+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3Xt-J/Gli3+,Rr26tm1Svok/Rr26tm1Svok
Genetic Background: involves: 129X1/SvJ * C3H/HeJ

Allelic Composition: Gli3Xt-J/Gli3+,Rr26tm1Svok/Rr26+
Genetic Background: involves: 129X1/SvJ * C3H/HeJ

Allelic Composition: Gli3tm1Urt/Gli3tm2Blnw
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0000564 syndactyly "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000565 oligodactyly "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000566 synostosis "osseous union of two bones that are not normally connected" [J:13049]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3tm2Blnw/Gli3tm2Blnw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3tm2Blnw/Gli3+,Shhtm1Chg/Shhtm1Chg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0000571 interdigital webbing "fold of skin, or web, between the toes that is not normally present" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000572 abnormal autopod morphology "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gli3tm2Blnw/Gli3+,Shhtm1Chg/Shhtm1Chg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Bmp4tm1Blh/Bmp4+,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S2/SvPas * C3H/HeJ * C57BL/6J * C57BL/6NHsd

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Hand2tm1.1Zllr/Hand2tm1.2Zllr,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129/Sv * BALB/cJ * C3H/HeJ * C57BL/6 * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0000579 abnormal nail morphology "structural or developmental anomaly of any of the thin, horny, translucent plates covering the dorsal surface of the distal end of each terminal phalanx of the digits" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000757 herniated abdominal wall "protrusions through and/or into the abdominal wall often resulting in the extrusion of viscera" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Ccr8tm1Gma/Ccr8tm1Gma
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000776 abnormal inferior colliculus "dysmorphology or disorganization of the paired inferior eminence of the mesencephalic tectum that is involved in preliminary visual processing, and control of eye movements" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

 MP:0000783 abnormal forebrain morphology "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0000790 abnormal stratification in cerebral cortex "abnormal formation or pattern of the layers of the cerebral cortex " [J:64289, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0000820 abnormal choroid plexus morphology "malformed or absent fringe of the tela choroidea of the cerebral ventricles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

 MP:0000823 abnormal lateral ventricle morphology "malformation or absence of cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

 MP:0000841 abnormal hindbrain morphology "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0000846 abnormal medulla oblongata "anomaly in the most caudal region of the brainstem that lies directly rostral to the spinal cord; includes regions responsible for autonomic functions such as digestion, breathing and control of heart rate" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0000849 abnormal cerebellum morphology "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
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Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0000857 abnormal cerebellar foliation "malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951]
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Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0000873 thin external granule cell layer "reduced thickness of the transient layer of the cerebellar cortex which is composed of dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]
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Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0000875 abnormal cerebellar Purkinje cell layer "any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

 MP:0000897 abnormal midbrain "malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

 MP:0000904 abnormal superior colliculus "dysmorphology or disorganization of the paired superior eminence of the mesencephalic tectum that is involved in auditory processing" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: C3H/HeJ * CD-1

Allelic Composition: Gli3tm1Alj/Gli3+,Tgif1tm1Caw/Tgif1tm1Caw,Tgif2tm1Dwot/Tgif2tm1Dwot,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA

 MP:0000925 abnormal floor plate morphology "malformation or absence of a transient group of neuroepithelial cells located at the ventral midline of the neural tube that profoundly influences the development of the vertebrate central nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tmem107schlei/Tmem107schlei
Genetic Background: involves: C3H/HeJ * C3HeB/FeJ * C57BL/6J

 MP:0000926 absent floor plate "missing ventral midline thinning of the developing neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35802]
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Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm5.1(GLI3)Alj/Gli2tm5.1(GLI3)Alj
Genetic Background: involves: 129S6/SvEvTac * Swiss Webster

Allelic Composition: Gli1tm2Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0000928 incomplete cephalic closure "arrest of the fusion of the cephalic neural folds" [J:12622]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

 MP:0000930 wavy neural tube "undulations in the embryonic neural tube" [J:37888]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0000933 abnormal rhombomere morphology "malformation of the transverse segments in the hindbrain region of the developing neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]
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Allelic Composition: X/SryCB
Genetic Background: C57BL/6JEi-Chr YCB/EiJ

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0000934 abnormal telencephalon development "malformed or incomplete differentiation of the anterior division of the embryonic prosencephalon " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:49840]
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Allelic Composition: X/SryCB
Genetic Background: C57BL/6JEi-Chr YCB/EiJ

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3Mos1/Gli3Mos1,Tg(Dct-LacZ)A12Jkn/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6J * CBA

 MP:0000935 abnormal folding of telencephalic vesicles "malformation of the stereotypic invaginations forming the paired diverticula of the telencephalon" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

 MP:0000937 abnormal motor neuron morphology "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: Gli2tm5.1(GLI3)Alj/Gli2tm5.1(GLI3)Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0000939 reduced motor neuron number "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: a/a,Mlphln/Mlphln,Tyrp1b/Tyrp1b
Genetic Background: C57L/J

Allelic Composition: Gli1tm2Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0000955 abnormal spinal cord morphology "malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli1tm2Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0001081 abnormal cranial ganglia morphology "any anomaly, deformity, or malformation of the groups of nerve cell bodies associated with the twelve cranial nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001175 abnormal lung morphology "malformed organ of respiration" [J:35802]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001176 abnormal lung development "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001178 pulmonary hypoplasia "reduced size of the respiratory organ due to incomplete development of all or part of the organ " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001181 absent lungs "missing organs of respiration" [J:51966, J:50768]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001216 abnormal epidermal layer morphology "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001231 abnormal basal cell layer morphology "structural anomaly of the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+,Ihhtm1Amc/Ihhtm1Amc,Tg(Col2a1-cre)3Amc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

 MP:0001286 abnormal eye development "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001293 anophthalmia "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]
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Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
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Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001302 eyelids open at birth "widely open eyes instead of closed at perinatal stage" [J:51966]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001333 absent optic nerve "absence of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

 MP:0001678 thick apical ectodermal ridge "increase in the thickness of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [MGI:tc]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001685 abnormal endoderm development "failure or abnormality in the formation of the endoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001699 enlarged embryo size "larger proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0001785 edema "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: C3H/HeJ * CD-1

 MP:0001786 skin edema "accumulation of an excessive amount of fluid in the skin" [J:65039]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Gli2tm3.1(Gli1)Alj/Gli2+,Gli3Xt-J/Gli3+
Genetic Background: either: (involves: 129S6/SvEvTac * C3H/HeJ) or (involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ)

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002081 perinatal lethality "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ccr8tm1Gma/Ccr8tm1Gma
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3Mos1/Gli3Xt-J
Genetic Background: involves: BALB/cJ * C3H/HeJ * C57BL/6J

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm3.1(Gli1)Alj/Gli2+
Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Ptgs2tm1.1Fun/Ptgs2tm1.1Fun
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: C3H/HeJ * NMRI

 MP:0002098 abnormal vibrissae morphology "irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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 MP:0002109 abnormal limb morphology "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ccr8tm1Gma/Ccr8tm1Gma
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3tm2Blnw/Gli3+,Shhtm1Chg/Shhtm1Chg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0002110 abnormal digit morphology "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp8btm1Blh/Bmp8btm1Blh
Genetic Background: B6.129-Bmp8btm1Blh

Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3Xt/Gli3+
Genetic Background: involves: 101/H * 129/Sv * C3H/HeH * C57BL/6

Allelic Composition: Gli3tm2Blnw/Gli3tm2Blnw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129/Sv * C3H/HeJ * C57BL/6

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129/Sv * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3tm2Blnw/Gli3+,Shhtm1Chg/Shhtm1Chg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt-2H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-2H/Gli3Xt-2H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-4H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-5H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-6H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-5H/Gli3Xt-5H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-6H/Gli3Xt-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-7H/Gli3Xt-7H
Genetic Background: mixed

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Skitm1Cco/Ski+
Genetic Background: involves: 129P2/OlaHsd * Black Swiss

 MP:0002114 abnormal axial skeleton morphology "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0002115 abnormal skeleton extremities morphology "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3tm1Urt/Gli3+
Genetic Background: either: 129P2/OlaHsd-Gli3Tm1Urt or (involves: 129P2/OlaHsd * C57BL/6)

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3Xt/?,Kif7maki/Kif7maki,Tg(Hlxb9-GFP)1Tmj/?
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6J * CBA/H * FVB/N

Allelic Composition: Cdk20tm1.1Jegg/Cdk20tm1.1Jegg,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S7/SvEvBrd * C3H/HeJ * FVB/N

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
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Allelic Composition: Gli3Xt/Gli3Xt,Glis1tm1Mnks/Glis1tm1Mnks
Genetic Background: mixed

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm1.2Zllr/Gli3Xt-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6J * NMRI

 MP:0002184 abnormal innervation "the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa2tm1.1Fmr/Hoxa2tm1.1Fmr,Tg(CAG-cre/ERT2)F34Fmr/0
Genetic Background: involves: 129/Sv * C57BL/6 * CD-1

 MP:0002196 acallosal "absence of the commissural plate interconnecting the cortical hemispheres of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0002233 abnormal nose morphology "any structural anomaly of the organ that is specialized for smell and is part of the respiratory system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0002237 abnormal nasal cavity morphology "any structural anomaly of the portion of the respiratory tract that extends from the nares to the pharynx; the nasal cavity is lined with ciliated mucosa" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0002239 abnormal nasal septum morphology "any structural anomaly of the structure that separates the two nasal cavities " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0002256 abnormal laryngeal cartilage morphology "any structural anomaly of the cartilagenous structures that support the larynx" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002543 brachyphalangia "abnormally short phalanges" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002544 brachydactyly "abnormally short digits" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0002621 delayed neural tube closure "delayed fusion of the neuroepithelial layer in early development" [J:79790, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0002654 spongiform encephalopathy "a neurodegenerative state characterized by the appearance of large vacuolated areas in the brain cells, resembling a sponge" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0002671 belted "the appearance of a stripe of white fur around the circumference of the abdomen" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt-J/Gli3+,Sox10tm1Weg/Sox10+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

Allelic Composition: Gli3Mos1/Gli3+,Sox10tm1Weg/Sox10+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J

 MP:0002728 absent tibia "missing the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3+
Genetic Background: involves: 101/H * 129/Sv * C3H/HeH * C57BL/6

Allelic Composition: Gli3tm2Blnw/Gli3tm2Blnw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129/Sv * C3H/HeJ * C57BL/6

Allelic Composition: Gli3tm2Blnw/Gli3+,Shhtm1Chg/Shhtm1Chg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3tm2Blnw/Gli3tm2Blnw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3tm2Blnw/Gli3+,Shhtm1Chg/Shhtm1Chg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3tm1.2Zllr/Gli3+,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0002765 short fibula "reduced length of the lateral and smaller of bone of the lower leg" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:12736]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0002884 abnormal branchial arches "malformation or anomaly in the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003052 omphalocele "protrusion of abdominal viscera at the base of the umbilical cord, with a covering membranous sac of peritoneum-amnion" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003069 abnormal superior semicircular canal "anomaly of the upper, superior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003072 abnormal metatarsal bone morphology "anomaly in the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003073 abnormal metacarpal bone morphology "anomaly in the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003109 short femur "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0003120 abnormal tracheal cartilage "any structural anomaly of the cartilaginous structures that support the trachea" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:97123]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003130 anal atresia "absence of a connection between the anal pit and the rectum" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91491]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003160 abnormal esophageal development "aberrant formation of the part of the digestive canal through which food passes from the pharynx to the stomach" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003161 absent lateral semicircular canal 
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003232 abnormal forebrain development "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gli3tm1Alj/Gli3+,Tgif1tm1Caw/Tgif1tm1Caw,Tgif2tm1Dwot/Tgif2tm1Dwot,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA

 MP:0003276 esophageal atresia "congenital blockage or absence of the lumen of the esophagus" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003321 tracheoesophageal fistula "an abnormal passage between the esophagus and the trachea, acquired or congenital, often associated with esophageal atresia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003419 delayed endochondral bone ossification "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
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Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3tm1.2Zllr/Gli3+,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003425 abnormal optic vesicle formation "anomalous formation of the hollow outgrowth from the lateral aspects of the embryonic forebrain from which the retina and optic nerve develop" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94391]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003451 absent olfactory bulb "absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003604 single kidney 
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003641 small lung "reduced size of the lung relative to normal" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95332]
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Allelic Composition: Gabra1tm2Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0003648 abnormal radial glial cell morphology "anomalous structure, number, or composition of the supporting cells of the developing central nervous system that guide neuronal migration during development and exchange metabolites with developing and migrating neurons; these cells differentiate into astrocytes and some neuronal types in the adult" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0003723 abnormal long bone morphology "malformation of any of the several elongated bones of the extremities " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003743 abnormal facial morphology "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003841 abnormal lambdoidal suture morphology "malformation of the articulation of the parietal bones and the occipital bone" [Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0003854 abnormal forelimb stylopod morphology 
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Hand2tm1.1Zllr/Hand2tm1.2Zllr,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129/Sv * BALB/cJ * C3H/HeJ * C57BL/6 * SJL

 MP:0003855 abnormal forelimb zeugopod morphology 
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Hand2tm1.1Zllr/Hand2tm1.2Zllr,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129/Sv * BALB/cJ * C3H/HeJ * C57BL/6 * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0003935 abnormal craniofacial development "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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 MP:0003938 abnormal ear development "developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004083 polysyndactyly "greater than 5 digits present on an autopod with interdigital webbing also present" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tulp3hhkr/Tulp3+
Genetic Background: involves: C3H/HeH * C3H/HeJ * C57BL/6

 MP:0004100 abnormal spinal cord interneuron morphology "malformation or absence of neurons that exclusively interact with other neurons in the spinal cord" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * Swiss Webster

Allelic Composition: Gli2tm5.1(GLI3)Alj/Gli2tm5.1(GLI3)Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL * CBA/H * Swiss Webster

Allelic Composition: Gli1tm2Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0004135 abnormal mammary gland embryonic development "aberration in the differentiation of the mammary gland during early embryogenesis" [smb:Susan M Bello, Mouse Genome Informatics Curator, llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Gli2tm2.1Alj/Gli2+,Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster

 MP:0004174 abnormal spine curvature "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004214 abnormal long bone diaphysis morphology "any structural anomaly of the main or mid section (shaft) of a long bone" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+,Ihhtm1Amc/Ihhtm1Amc,Tg(Col2a1-cre)3Amc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

 MP:0004268 abnormal optic stalk morphology "any structural anomaly of the narrow, proximal portion of the optic vesicle which connects the embryonic eye and forebrain" [ISBN:0-914294-08-3 "Gray s Anatomy"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004269 abnormal optic cup morphology "any structural anomaly of double walled stuctured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004320 split sternum "the appearance of an abnormal division in the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

 MP:0004321 short sternum "reduced length of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0004340 short scapula "reduced length of either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0004342 scapular bone foramen "presence of a hole in either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15+
Genetic Background: involves: C3H * C57BL/6J

 MP:0004343 small scapula "reduced size of either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15de-H
Genetic Background: involves: C3H * C57BL/6J

 MP:0004345 abnormal acromion morphology "any structural anomaly of the lateral end of the spine of the scapula which projects as a broad flattened process and articulates with the clavicle, and forms the point of the shoulder" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tbx15de-H/Tbx15de-H
Genetic Background: involves: C3H * C57BL/6J

 MP:0004351 short humerus "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3tm1.2Zllr/Gli3+,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0004355 short radius "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0004358 bowed tibia "increased curvature of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004359 short ulna "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0004360 absent ulna "missing the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0004361 bowed ulna "increased curvature of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0004372 bowed fibula "increased curvature of the lateral and smaller bone of the lower limb" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004374 bowed radius "increased curvature of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0004457 abnormal orbitosphenoid bone morphology "any structural anomaly of the bone that is situated in the orbit on either side of the presphenoid; it generally forms a part of the sphenoid in the adult, and may be independent in the young" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004462 small basisphenoid bone "reduced size of part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004463 basisphenoid bone foramen "the presence of one or more holes in part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004506 abnormal pubic bone morphology "any structural anomaly in the forward portion of either of the hipbones, at the juncture forming the front arch of the pelvis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004537 abnormal palatine shelf "any structural anomaly of the palatine bone; normally fuses with maxillary shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004544 absent esophagus "absence of the part of the digestive canal through which food passes from the pharynx to the stomach" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0004576 abnormal foot plate morphology "any structural anomaly of the distal elements of the developing limb of vertebrates that will give rise to the pedal appendages (e.g. hand, foot, paw)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-J/Gli3+
Genetic Background: involves: C3H * CD-1

 MP:0004599 abnormal vertebral arch morphology "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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 MP:0004609 vertebral fusion "the union of one or more vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004613 fusion of vertebral arches "improper union of the dorsal part of adjacent vertebra" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli2tm1Alj/Gli2+,Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004622 sacral vertebral fusion "the union of one or more sacral vertebrae into a single structure in species where this does not normally occur" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3tm1.2Zllr/Gli3+,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004784 abnormal anterior cardinal vein morphology "any structural anomaly of the two paired veins draining the cephalic part of the body" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0004948 abnormal neuronal precursor proliferation "any anomaly in the ability of a neuroblast population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli1tm2Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0004979 abnormal neuronal precursor cell number "deviation from the normal count of the neuroblast embryonic cells that develop into nerve cells or neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli1tm2Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0004980 increased neuronal precursor cell number "increased number of the neuroblast embryonic cells that develop into nerve cells or neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli1tm2Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

Allelic Composition: Gli2tm1Alj/Gli2+,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0005170 cleft lip "defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0005176 eyelids fail to open "eyes remain shut throughout life" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0005225 abnormal vertebrae development "anomalous formation of the vertebrae from the sclerotome" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

 MP:0005236 abnormal olfactory nerve morphology "anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0005237 abnormal olfactory tract morphology "structural anomaly of the nervelike, white band composed primarily of nerve fibers originating from the mitral cells and tufted cells of the olfactory bulb, but also containing the scattered cells of the anterior olfactory nucleus " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34460]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0005306 abnormal phalanx morphology "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli3Xt/Gli3+
Genetic Background: involves: 101/H * 129/Sv * C3H/HeH * C57BL/6

Allelic Composition: Gli3tm2Blnw/Gli3tm2Blnw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129/Sv * C3H/HeJ * C57BL/6

Allelic Composition: Gli3tm2Blnw/Gli3+,Shhtm1Chg/Shhtm1Chg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt-2H/Gli3Xt-2H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-5H/Gli3Xt-5H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt-6H/Gli3Xt-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0005313 absent adrenal gland "missing endocrine glands that are normally located above the kidney and responsible for hormone and epinepherine secretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56651]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005408 hypopigmentation "dilution of the pigment in the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Mos1/Gli3+
Genetic Background: involves: BALB/cJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3+,Sox10tm1Weg/Sox10+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

Allelic Composition: Gli3Mos1/Gli3+,Sox10tm1Weg/Sox10+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J

 MP:0005430 absent fibula "missing the lateral and shorter of the two bones of the lower leg" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:86196]
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Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr,Pkdcctm1.2Azun/Pkdcctm1.2Azun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli2tm1Alj/Gli2+,Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * CD-1

Allelic Composition: Gli3TgBR/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6J * CBA/H

 MP:0005537 abnormal cerebral aqueduct "anomalous structure of the channel in the mesencephalon that connets the third and fourth ventricles" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0005631 decreased lung weight "less than the normal state of the physical heaviness of the lung" [RGD:Rat Genome Database submission]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0005650 abnormal limb bud morphology "aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:61460]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0006009 abnormal neuronal migration "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0006030 abnormal otic vesicle formation "anomalous formation of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:57313:]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0006104 abnormal tectum morphology "any structural alterations or malfunction of the rostral part of the midbrain roof" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator, J:65762]
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Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0006254 thin cerebral cortex "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0006279 abnormal limb development "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Hand2tm1.1Zllr/Hand2tm1.2Zllr,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129/Sv * BALB/cJ * C3H/HeJ * C57BL/6 * SJL

 MP:0006280 abnormal digit development "anomaly in the formation of the digits" [J:70592, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Relnrl-Alb2/Relnrl-Alb2
Genetic Background: involves: C3H/HeJ * C57BL/6J

Allelic Composition: Gli3add/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H * SJL

 MP:0006292 abnormal olfactory placode morphology "any structural abnormality in the paired ectodermal placodes that come to lie in the bottom of the olfactory pits as the pits are deepened by the growth of the surrounding medial and lateral nasal processes" [J:62024, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0006322 abnormal perichondrium morphology "any structural anomaly of the fibrous connective tissue that surrounds all non-joint end cartilage" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", J:117033, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Ihhtm1Amc/Ihhtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

 MP:0006343 enlarged first branchial arch "increased size of the first branchial arch" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0008160 increased diameter of humerus "increased width of the cross-sectional distance that extends from one lateral edge of the humerus, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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 MP:0008161 increased diameter of radius "increased width of the cross-sectional distance that extends from one lateral edge of the radius, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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 MP:0008163 increased diameter of ulna "increased width of the cross-sectional distance that extends from one lateral edge of the ulna, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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 MP:0008223 absent hippocampal commissure "absence of the triangular subcallosal plate of commissural fibers resulting from the converging of the right and left fornix bundles which exchange numerous fibers and which curve back in the contralateral fornix to end in the hippocampus of the opposite side" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0008227 absent anterior commissure "absence of a round bundle of nerve fibers that crosses the midline of the brain near the anterior limit of the third ventricle" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0008272 abnormal endochondral bone ossification "anomaly in the process of the formation of bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958]
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Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008275 failure of endochondral bone ossification "failure to initiate or a block in the process of the formation of bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Gli3tm3.1Blnw/Gli3+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0008540 abnormal cerebrum morphology "any structural anomaly of the largest part of the brain, derived from the telencephalon, and is composed of a right and a left hemisphere each which contains an outer cerebral cortex and a subcortical basal ganglia; cerebral functions include sensorimotor, emotional, and intellectual activities" [MESH:A08.186.211.730.885.287]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0008762 embryonic lethality "death of an animal in the embryonic period (Mus: up to E14)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Mos1/Gli3Xt-J
Genetic Background: involves: BALB/cJ * C3H/HeJ * C57BL/6J

 MP:0008789 abnormal olfactory epithelium morphology "any structural anomaly in the epithelial cells that line the interior of the nose" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli3tm1Alj/Gli3+,Tgif1tm1Caw/Tgif1tm1Caw,Tgif2tm1Dwot/Tgif2tm1Dwot,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA

 MP:0008818 abnormal interfrontal bone morphology "any structural anomaly or presence of a bone between the frontal bones in the skull; an extra bony plate within the anterior fontanelle that is not usually present" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0008854 bleb "presence of a blister-like, nearly hemispherical structure formed during embryonic development filled with air, serous fluid or blood" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0008915 fused carpal bones "anomaly of the nine nodular bones of the joint between the forelimb bones and the front paws/hands resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0008919 fused tarsal bones "anomaly of the eight bones of the instep of the paw/foot resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0008985 hemimelia "congenital absence of part of an extremity, such as absent fibula with the tibia present" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Gli3tm1.2Zllr/Gli3tm1.2Zllr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009003 abnormal vibrissa number "any anomaly in the number of the stiff hairs projecting from the face around the nose of most mammals which act as touch receptors" [MESH:A13.950, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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 MP:0009004 progressive hair loss "thinning of hair (coat) over time, usually in a defined pattern, until entirely gone with no recurrent growth" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli2tm3.1(Gli1)Alj/Gli2+,Gli3Xt-J/Gli3+
Genetic Background: either: (involves: 129S6/SvEvTac * C3H/HeJ) or (involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ)

 MP:0009039 absent inferior colliculus "absence of the paired inferior eminence of the mesencephalic tectum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

 MP:0009048 enlarged tectum "increased size of the rostral part of the midbrain roof" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Fgf8tm1.4Mrt/Fgf8+,Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

Allelic Composition: Gli3tm1Alj/Gli3tm1Alj,Tg(Nes-cre)1Kln/?
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL

Allelic Composition: En1tm2(cre)Wrst/?,Gli3tm1Alj/Gli3tm1Alj,Smotm2Amc/Smotm2Amc
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6

 MP:0009049 abnormal hallux morphology "any structural anomaly of the first or primary digit of the foot" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0009569 abnormal left lung morphology "any structural anomaly of the organ of respiration located on the left side of the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gabra1tm2Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0009571 abnormal right lung accessory lobe morphology 
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Allelic Composition: Gabra1tm2Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0009573 abnormal right lung middle lobe morphology 
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0009574 abnormal right lung caudal lobe morphology 
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Allelic Composition: Gabra1tm2Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0009719 reduced cerebellar foliation "the cerebellar lobules are reduced in size or number" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6 * CBA/H

Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1.1Alj/Gli3Xt
Genetic Background: involves: 101/H * 129S6/SvEvTac * C3H/HeH * C57BL/6 * CBA/H

 MP:0009743 preaxial polydactyly "duplication of all or part of the first ray on one or more of the autopods" [PMID:19125433]
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Allelic Composition: Gli3TgBR/Gli3TgBR
Genetic Background: involves: C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Hand2tm1.1Zllr/Hand2tm1.2Zllr,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129/Sv * BALB/cJ * C3H/HeJ * C57BL/6 * SJL

 MP:0009744 postaxial polydactyly "duplication of all or part of any of the rays except the first ray on one or more of the autopods" [PMID:19125433]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Hand2tm1.1Zllr/Hand2tm1.2Zllr,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129/Sv * BALB/cJ * C3H/HeJ * C57BL/6 * SJL

 MP:0009770 abnormal optic chiasm morphology "an anomaly in the flattened quadrangular body that is the point of crossing of the fibers of the optic nerves" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0009783 abnormal melanoblast morphology "any structural anomaly of a cell that originates from the neural crest and differentiates into a pigment cell" [CL:0000541]
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Allelic Composition: Gli3Mos1/Gli3Xt-J
Genetic Background: involves: BALB/cJ * C3H/HeJ * C57BL/6J

Allelic Composition: Gli3Mos1/Gli3+,Tg(Dct-LacZ)A12Jkn/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6J * CBA

Allelic Composition: Gli3Mos1/Gli3Mos1,Tg(Dct-LacZ)A12Jkn/0
Genetic Background: involves: BALB/cJ * C57BL/6 * C57BL/6J * CBA

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli1tm2Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

 MP:0010082 sternebra fusion "appearance of one or more sternebrae as a single structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3Xt-3H/Gli3+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0010371 abnormal epiglottis morphology "any structural anomaly of the most superior of the laryngeal cartilages, which is found at the root of the tongue and folds back over the entrance to the larynx during swallowing, preventing inhalation of food or drink" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010883 trachea stenosis "abnormal narrowing or constriction of the trachea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0010885 absent trachea "absence of the tube descending from the larynx and branching into the right and left main bronchi" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0010906 abnormal lung bud morphology "any structural anomaly of the primary outgrowth of the embryonic trachea i.e. blunt end of the respiratory diverticulum which grows ventrally out of the proximal end of the foregut, then extends caudally and divides into two, forming the anlage of a primary bronchus and all its branches" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Gli3tm1Blnw/Gli3Xt-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Gli3tm2Blnw/Gli3tm2Blnw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+,Ihhtm1Amc/Ihhtm1Amc,Tg(Col2a1-cre)3Amc/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Gli3tm3.1Blnw/Gli3tm3.1Blnw,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Dtnatm1Jrs/Dtnatm1Jrs,Utrntm1Jrs/Utrntm1Jrs
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
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Allelic Composition: Gli3Xt-3H/Gli3Xt-3H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Gli2tm3(Gli1)Alj/Gli2tm3(Gli1)Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C3H/HeJ * C57BL/6

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011259 abnormal cephalic neural fold morphology "any structural anomaly of the elevated margins of the neural groove that are located in the future cephalic region of the embryo" [ISBN:0-683-40008-8, MGI:csmith]
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Allelic Composition: Gli3tm1Alj/Gli3+,Tgif1tm1Caw/Tgif1tm1Caw,Tgif2tm1Dwot/Tgif2tm1Dwot,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA

 MP:0011362 ectopic adrenal gland "an adrenal gland located outside of its normal position" [MGI:anna]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0011505 camptomelia "a skeletal dysplasia characterized by the bending of the long bones of the extremities" [ISBN:0-683-40008-8]
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Allelic Composition: Gli3tm1Urt/Gli3tm1Urt
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011727 ectopic ovary "appearance of an ovary in a region where it is not normally found (topographical anomaly)" [MGI:csmith]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0011964 increased total retina thickness "increased width of the retina through the center plane" [MGI:csmith]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0012101 acoria "absence of the pupil of the eye" [MGI:anna]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0012132 abnormal midbrain-hindbrain boundary morphology "any structural anomaly of the midbrain-hindbrain domain of the embryonic brain that is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; normally, an organizing center located at the boundary patterns the midbrain and hindbrain primordia of the neural plate" [MGI:anna]
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Allelic Composition: Gli3tm1.1Alj/Gli3tm1.1Alj
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Gli3tm1Alj/Gli3tm1Alj,Tg(Nes-cre)1Kln/?
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL

 MP:0012139 increased forebrain size "greater than average size of the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)" [GO:0048853]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0012667 split sternal manubrium "the appearance of an abnormal division of the cranial most segment of the sternum" [MGI:anna]
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Allelic Composition: Gli3Pdn/Gli3Pdn
Genetic Background: involves: Jcl:ICR

 MP:0012706 decreased embryonic neuroepithelial cell proliferation "decrease in the expansion rate of the cells of the embryonic neuroepithelium by cell division" [CL:0000710, MGI:anna]
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Allelic Composition: Gli3tm1Alj/Gli3+,Tgif1tm1Caw/Tgif1tm1Caw,Tgif2tm1Dwot/Tgif2tm1Dwot,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA

 MP:0013362 absent pineal gland "absence of the unpaired epithalamic structure that is shaped like a tiny pine cone and located above the posterior commissure near the level of the habenular complex and the sylvian aqueduct; the pineal is both a circumventricular organ and an endocrine organ that secretes melatonin, a serotonin-derived hormone involved in the regulation of circadian rhythms" [MGI:Anna]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0013443 Harderian gland hyperplasia "overdevelopment or increased size, usually due to an increased number of cells, of the sebaceous gland that is located behind the eyeball and excretes fluid that facilitates movement of the nictitating membrane" [MGI:Anna]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0013496 abnormal trachea development "aberrant formation or incomplete differentiation of the tube descending from the larynx and branching into the right and left main bronchi" [MGI:Anna]
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Allelic Composition: Gli2tm1Alj/Gli2tm1Alj,Gli3Xt/Gli3Xt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0013529 decreased nipple number "fewer than the expected number of structures located on the apex of the mammary gland on the integument surface into which the lactiferous ducts open; normal female mice have five pairs of mammary glands and nipples (males have no nipples); two pairs of nipples are situated in the abdomino-inguinal region (inguinal group) and three pairs in the ventral thoracic region (pectoral or thoracic group)" [http://www.informatics.jax.org/cookbook/figures/figure48.shtml, http://www.informatics.jax.org/cookbook/figures/figure50.shtml, MGI:Anna]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0013720 abnormal mammary line morphology "any structural anomaly of either of the presumptive bilateral epidermal ridges (milk lines) formed at the onset of mammogenesis and running in an anteroposterior direction ventrally between fore- and hindlimbs, one line along each flank of the embryo; in mouse, mammary gland development begins shortly after mid-gestation (about E10.5); epidermal cells within the milk line become columnar and multilayered, defining a ridge that protrudes above and below the plane of the single-layered primitive epidermis or periderm; by E11.5, five pairs of lens-shaped placodes form along the mammary line at the site of each future nipple" [PMID:12558599, PMID:16524451]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0013721 abnormal mammary placode morphology "any structural anomaly of the transient lens-shaped thickening of surface ectoderm that will give rise to the mammary bud proper; in mouse, five pairs of symmetrically positioned mammary placodes (three thoracic and two inguinal) form at reproducible locations along the mammary line at E11.5; the individual pairs develop asynchronously and in a distinct order; pair 3 is first, followed by pair 4, then by pairs 1 and 5 (which develop together), and finally by pair 2; the orientation of placodal cells is not uniform, suggesting that placodes are formed by migration of cells from the mammary line; between E11.5 and E12.5, each mammary placode expands and invaginates into the underlying mesenchyme to form an early bulb-shaped mammary bud " [PMID:16168142, PMID:20484386]
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Allelic Composition: Gli2tm2.1Alj/Gli2+,Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster

 MP:0013785 abnormal mammary gland bud morphology "any structural anomaly of the morphologically distinct bulb of epithelial cells formed once each mammary placode expands and invaginates into the underlying mesenchyme; in mouse embryos at E12.5, each epithelial bud with its contiguous mesenchyme is elevated above the surrounding ectoderm as a knob or dome; at E13.5, the buds sink into the underlying dermal mesenchyme, and by E14.5 they can no longer be detected externally; in female mouse embryos, five pairs of anlagen or buds are formed along the mammary line between E12.5 and E14.5 by proliferation of basal epidermal cells; while further mammary development is temporarily arrested in females, androgen receptor activation in male embryos causes degeneration of the buds between E13.5 and E15.5; in female mice, further development is resumed at around E15.5 when each bud elongates to form a mammary cord (sprout), invading the underlying fat pad precursor" [http://www.informatics.jax.org/greenbook/frames/frame13.shtml, MGI:Anna, PMID:12558599]
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Allelic Composition: Gabra1tm2Geh/Gabra1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

Allelic Composition: Gli2tm3(Gli1)Alj/Gli2tm3(Gli1)Alj,Gli3Xt-J/Gli3+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster

Allelic Composition: Gli2tm2.1Alj/Gli2+,Gli3Xt-J/Gli3Xt-J
Genetic Background: involves: 129S6/SvEvTac * Black Swiss * C3H/HeJ * C57BL/6 * Swiss Webster

 MP:0030031 abnormal forehead morphology "any structural anomaly of the part of the face above the eyes; in human anatomy, the forehead is the fore part of the head, an area of the head bounded by three features, two of the skull and one of the scalp; the top of the forehead is marked by the hairline, the edge of the area where hair on the scalp grows while the bottom of the forehead is marked by the supraorbital ridge, the bone feature of the skull above the eyes; the two sides of the forehead are marked by the temporal ridge, a bone feature that links the supraorbital ridge to the coronal suture line and beyond" [HP:0000290]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0030203 short nasal septum "reduced length of the dividing wall that runs down the midline of the nose, separating the nasal cavity into the two nostrils" [MGI:anna]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0030205 thick nasal septum "increased width of the dividing wall that runs down the midline of the nose, separating the nasal cavity into the two nostrils" [HP:0009746, MGI:anna]
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Allelic Composition: Gli3Xt/Gli3Xt
Genetic Background: involves: 101/H * C3H/HeH * CBA/H

 MP:0030353 wide sagittal suture "an abnormally increased width of the sagittal suture for age-related norms" [MGI:anna]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0030356 premature lambdoid suture closure "early closure of the lambdoid suture of the skull" [MGI:anna]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

 MP:0030431 wide metopic suture "an abnormally increased width of the metopic suture for age-related norms" [MGI:anna]
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Allelic Composition: Gli3Xt-J/Gli3Xt-J
Genetic Background: B6.C3-Gli3Xt-J/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005469 P05132 / Prkaca / protein kinase, cAMP dependent, catalytic, alpha / P17612* / protein kinase cAMP-activated catalytic subunit alpha*  / reaction
 ENSMUSG00000005034 P68181 / Prkacb / protein kinase, cAMP dependent, catalytic, beta / P22694* / protein kinase cAMP-activated catalytic subunit beta*  / reaction
 ENSMUSG00000022812 Gsk3b / Q9WV60 / glycogen synthase kinase 3 beta / P49841*  / reaction
 ENSMUSG00000022400 Rbx1 / P62878 / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed / P62877* / ring-box 1*  / reaction / complex
 ENSMUSG00000025231 Sufu / Q9Z0P7 / SUFU negative regulator of hedgehog signaling / Q9UMX1*  / reaction / complex
 ENSMUSG00000032308 Ulk3 / Q3U3Q1 / unc-51-like kinase 3 / Q6PHR2*  / reaction
 ENSMUSG00000057522 Spop / Q6ZWS8 / Mus musculus speckle-type POZ protein (Spop), transcript variant 2, mRNA. / O43791* / speckle type BTB/POZ protein*  / reaction / complex
 ENSMUSG00000039153 Runx2 / Q08775 / runt related transcription factor 2 / Q13950*  / complex / reaction
 ENSMUSG00000024576 Q8BK63 / Csnk1a1 / casein kinase 1, alpha 1 / P48729*  / reaction
 ENSMUSG00000004364 Cul3 / Q9JLV5 / Cullin-3 / Q13618*  / complex / reaction
 ENSMUSG00000026361 Cdc73 / Q8JZM7 / Parafibromin / Q6P1J9* / cell division cycle 73*  / complex / reaction






 

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