MP:0000023 | abnormal ear distance/ position | "anomaly in the space between or the placement of the outer ears " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0000024 | lowered ear position | "outer ears which are situated below the normal location " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0000074 | abnormal neurocranium morphology | "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
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MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0000120 | malocclusion | "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Nos3tm1Unc/Nos3tm1Unc Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: Nos3tm1Unc/Nos3tm1Unc Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000160 | kyphosis | "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0000161 | scoliosis | "lateral and rotational curvature of the spine" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53770, J:66943] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0000266 | abnormal cardiac morphology | "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Pkd1tm1Shh/Pkd1tm1.1Pcha Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
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MP:0000267 | abnormal cardiac development | "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370] |
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Allelic Composition: Nos3tm1Unc/Nos3tm1Unc Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000269 | abnormal looping morphogenesis | "atypical bending of the primitive heart tube during early development" [J:27443] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3Ka/Zic3Ka Genetic Background: involves: BALB/cOlaHsd * C3H/HeH
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
Allelic Composition: Zic3tm2.1Jwb/Y,Tg(T-cre)1Lwd/0 Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C3H * C57BL/6
Allelic Composition: Zic3tm1.1Smwa/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Zic3tm1.1Smwa/Y,Tg(T-cre)1Lwd/0 Genetic Background: involves: C3H * C57BL/6
Allelic Composition: Zic3Ka/Y Genetic Background: involves: BALB/cOlaHsd * C3H/HeH
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MP:0000284 | double outlet right ventricle | "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0000432 | abnormal head morphology | "anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
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MP:0000441 | wide skull | |
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Allelic Composition: Thrbtm1Df/Thrbtm1Df Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000454 | abnormal jaw morphology | "malformation of the bony framework of the mouth where the teeth are held" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mapkapk2tm1Mgl/Mapkapk2tm1Mgl,Mapkapk3tm1.1Lex/Mapkapk3tm1.1Lex Genetic Background: involves: 129P2/OlaHsd * 129S/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0000457 | maxilla hypoplasia | "arrested growth or atrophy of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0000458 | abnormal mandible morphology | "malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0000531 | right pulmonary isomerism | "bilaterally symmetric right lung pattern (or altered asymmetric patterning of the lung)" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, J:58530] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000585 | kinked tail | "a sharp bend or zig-zag in the tail" [J:61295] |
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Allelic Composition: Thrbtm1Df/Thrbtm1Df Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
Allelic Composition: Zic3Ka/Zic3+ Genetic Background: involves: BALB/cOlaHsd * C3H/HeH
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
Allelic Composition: Zic3tm2.1Jwb/Y,Tg(T-cre)1Lwd/0 Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C3H * C57BL/6
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MP:0000592 | short tail | "reduced length of tail compared to control " [J:55583] |
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Allelic Composition: Thrbtm1Df/Thrbtm1Df Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
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MP:0000598 | abnormal liver morphology | "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170] |
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Allelic Composition: Nos3tm1Unc/Nos3tm1Unc Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000644 | dextrocardia | "cardiac apex pointing to the right as opposed to the normal levocardia" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0000694 | spleen hypoplasia | "small size due to reduced cell number in the spleen" [J:43971] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000755 | hindlimb paralysis | "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0000783 | abnormal forebrain morphology | "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000786 | abnormal neuroepithelial layer differentiation | "malformation or arrest of differentiation or patterning of the epithelial layer of the brain" [J:45302] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000807 | abnormal hippocampus morphology | "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000830 | abnormal diencephalon morphology | "any malformation or absence of the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000850 | absent cerebellum | "missing the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000897 | abnormal midbrain | "malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000914 | exencephaly | "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0000919 | cranioschisis | "incomplete closure of the skull, usually congenital " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
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MP:0000929 | open neural tube | "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0001304 | cataracts | "complete or partial opacity of the lens" [J:65031] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0001539 | decreased number of caudal vertebrae | "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Thrbtm1Df/Thrbtm1Df Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
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MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * Swiss
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0001680 | abnormal mesoderm development | "failure or abnormality in the formation of the mesoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0001685 | abnormal endoderm development | "failure or abnormality in the formation of the endoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0001688 | abnormal somite development | "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0001695 | abnormal gastrulation | "anomalous development and invagination of the embryonic germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * Swiss
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1.1Smwa/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: C57BL/6 * CBA
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MP:0001700 | abnormal embryo turning | "atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0001706 | abnormal left-right axis patterning | "anomaly in the formation or development of the body or a specific organ of the body in relation to the left and right sides of the body or organ" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zic3Ka/Zic3+ Genetic Background: involves: BALB/cOlaHsd * C3H/HeH
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1.1Smwa/Y,Tg(T-cre)1Lwd/0 Genetic Background: involves: C3H * C57BL/6
Allelic Composition: Zic3Ka/Y Genetic Background: involves: BALB/cOlaHsd * C3H/HeH
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MP:0001730 | embryonic growth arrest | "the cessation of development beyond a particular stage" [J:17509] |
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Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * Swiss
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0001890 | anencephaly | "absence of the bones of the cranial vault and absent or rudimentary cerebral and cerebellar hemispheres, brainstem, and basal ganglia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:31571] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
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Allelic Composition: Thrbtm1Df/Thrbtm1Df Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Thrbtm1Df/Thrbtm1Df Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0002085 | abnormal embryonic tissue morphology | "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * Swiss
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0002086 | abnormal extraembryonic tissue morphology | "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * Swiss
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0002092 | abnormal eye morphology | "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0002114 | abnormal axial skeleton morphology | "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nos3tm1Unc/Nos3tm1Unc Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0002127 | abnormal cardiovascular system morphology | "abnormal development of the heart or vascular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nos3tm1Unc/Nos3tm1Unc Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0002151 | abnormal neural tube morphology/development | "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
Allelic Composition: Zic3tm1.1Smwa/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: C57BL/6 * CBA
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Adcy7tm1.1Pcst/Adcy7tm1.1Pcst,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Zic3tm2.1Jwb/Zic3tm2.1Jwb Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6J
Allelic Composition: Nkx2-5tm1(cre)Rjs/Nkx2-5+,Zic3tm2.1Jwb/Y Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6J
Allelic Composition: Zic3tm2.1Jwb/Y,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6J * CBA/J
Allelic Composition: Mesp1tm2(cre)Ysa/Mesp1+,Zic3tm2.1Jwb/Y Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA/JNCrlj
Allelic Composition: Zic3tm1.1Smwa/Y,Nkx2-5tm1(cre)Rjs/Nkx2-5+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm1.1Smwa/Y,Tg(Mef2c-cre)#Blk/0 Genetic Background: Not Specified
Allelic Composition: Zic3tm1.1Smwa/Y,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: C57BL/6J * CBA/J
Allelic Composition: Zic3tm1.1Smwa/Y,Tg(Myh7-cre)1Jmk/0 Genetic Background: Not Specified
Allelic Composition: Zic3tm1.1Smwa/Y,Tg(Nodal-cre)16Hmd/0 Genetic Background: involves: C57BL/6
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MP:0002231 | abnormal primitive streak morphology | "anomaly in the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0002258 | abnormal cricoid cartilage morphology | "any structural anomaly of the most inferior of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0002621 | delayed neural tube closure | "delayed fusion of the neuroepithelial layer in early development" [J:79790, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0002766 | situs inversus | "lateral transposition of the viscera of the thorax and abdomen, sometimes incomplete" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
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MP:0002767 | situs ambiguus | "abnormal organ position" [J:62608] |
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Allelic Composition: Thrbtm1Df/Thrbtm1Df Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
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MP:0003036 | vertebral transformation | "homeotic transformation of a specific vertebrae to adopt the fate of another" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0003056 | abnormal hyoid bone | "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0003085 | abnormal egg cylinder morphology | "anomaly in the transient cup-like structure of the epiblast that consists of a single layer of embryonic cells" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3Ka/Y Genetic Background: involves: BALB/cOlaHsd * C3H/HeH
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MP:0003178 | left pulmonary isomerism | "bilaterally symmetric left lung pattern (or altered asymmetric patterning of the lung)" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93051] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0003345 | decreased number of ribs | "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0003886 | abnormal embryonic epiblast morphology | "anomaly in the development/organization of the tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0003890 | abnormal embryonic-extraembryonic boundary morphology | "anomaly in the normal development /maintenance of the connection between the embryo proper and extraembryonic tissues" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3Ka/Y Genetic Background: involves: BALB/cOlaHsd * C3H/HeH
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MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0004066 | abnormal Henson s node morphology | "malformation of cells in the small pit at the anterior end of the primitive streak that are important in determining left-right asymmetry" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1.1Smwa/Y,Tg(T-cre)1Lwd/0 Genetic Background: involves: C3H * C57BL/6
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MP:0004073 | caudal body truncation | "caudal part of body truncated with anterior portion relatively normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0004110 | transposition of great arteries | "cardiovascular malformation in which the aorta arises from the right ventricle while the pulmonary artery arises from the left ventricle" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0004131 | abnormal embryonic ciliary morphology | "any structural malformation of the earliest cilia of the mouse embryo found on the cells of the embryonic node" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0004133 | heterotaxia | "abnormal arrangement of organs or parts of the body in relation to each other" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
Allelic Composition: Zic3tm2.1Jwb/Y,Tg(T-cre)1Lwd/0 Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C3H * C57BL/6
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MP:0004157 | interrupted aortic arch | "complete discontinuation/blockage between the ascending and descending aorta; includes Type A, interruption distal to the subclavian artery that is ipsilateral to the second carotid artery, and Type B, interruption between second carotid artery and ipsilateral subclavian artery" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0004158 | right aortic arch | "the aortic arch lies to the right of the trachea and esophagus; results from persistance of the entire right dorsal arch and involution of a segment of the left arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0004252 | abnormal direction of looping morphogenesis | "deviation from the normal rightward direction of cardiac looping" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
Allelic Composition: Zic3Ka/Y Genetic Background: B6.C(C3H)-Zic3Ka
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MP:0004559 | small allantois | "reduced size of the fetal membrane which contributes to the formation of the umbilical cord and placental blood vessels" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0004713 | split notochord | "the appearance of an abnormal division in the axial fibrocellular cord in embryos around which develops the vertebral primordia" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0004871 | premaxilla hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, in the anterior and interior portion of the maxilla" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0005034 | abnormal anus morphology | "structural anomaly of the lower opening of the digestive tract" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0005221 | abnormal rostral-caudal axis patterning | "anomaly in the development or formation of the axis that runs from the head to the tail of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0005224 | abnormal left-right axis symmetry of the somites | "anomaly in the formation or development of the somites in relation to the left and right sides of the body " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0005236 | abnormal olfactory nerve morphology | "anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0005270 | abnormal zygomatic bone morphology | "anomalous structure of the bone that forms the prominence of the cheek" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0005657 | abnormal neural plate morphology | "malformation or absence of the neuroectodermal area of the embryo s dorsal surface that develops into the neural tube and neural crest" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator, J:68142] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0006007 | abnormal basal ganglion morphology | "malformation or absence of any of a group of nuclei associated with the ability to carry out willed movements, including the caudate, putamen, nucleus accumbens, globus pallidus, substantia nigra, and subthalamic nucleus" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0006063 | abnormal inferior vena cava morphology | "structural malformation in the principal vein draining blood from the lower portion of the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0006065 | abnormal heart position | "the heart is displaced from the normal left-sided position and/or orientation" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0008533 | abnormal anterior visceral endoderm | "any structural anomaly of the extraembryonic tissue that is responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate patterning of adjacent embryonic tissue" [PMID:17078044] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0008818 | abnormal interfrontal bone morphology | "any structural anomaly or presence of a bone between the frontal bones in the skull; an extra bony plate within the anterior fontanelle that is not usually present" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
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MP:0009331 | absent primitive node | "absence of the regional thickening of cells at the rostral tip of the vertebrate primitive streak through which gastrulating cells migrate anteriorally to form tissues in the future head and neck; this region organizes the formation of the three embryonic layers and establishes the longitudinal axis and the polarity of the embryo" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0009916 | absent hyoid bone greater horns | "absence of the larger and more lateral of the paired processes on either side of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0010402 | ventricular septal defect | "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0010403 | atrial septal defect | "abnormal communications between the two upper chambers of the heart, including such defects in any or all of the ostium primum, ostium secundum, sinus venosus, and coronary sinus regions" [MESH:C14.240.400.560.375] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0010807 | abnormal stomach position or orientation | "the stomach is displaced from the normal left-sided position and/or orientation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0010808 | right-sided stomach | "stomach is present on the right side of the body instead of the left" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0010853 | abnormal lung position or orientation | "the lung is displaced from the normal position and/or has an altered left/right orientation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0010854 | lung situs inversus | "anomaly in the asymmetry of the lung such that lung lobes on both the left and right side have the morphology normally seen on the opposite side of the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0011092 | complete embryonic lethality | "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Zic3Bn/Zic3Bn Genetic Background: BNT/LeJ
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * Swiss
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MP:0011109 | partial lethality throughout fetal growth and development | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Zic3tm2.1Jwb/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C57BL/6 * CBA
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MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Tbx21tm1Glm/Tbx21+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Zic3tm2.1Jwb/Y,Tg(T-cre)1Lwd/0 Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvSvBrd * C3H * C57BL/6
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MP:0011660 | ectopia cordis | "congenital condition in which the heart is exposed and/or protruding from the thorax due to abnormal development of the sternum, pericardium and/or the abdominal wall" [ISBN:0-683-40008-8] |
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Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0012156 | rostral-caudal axis duplication | "partial or complete duplication of rostral-caudal axis structures" [MGI:anna] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0012685 | abnormal primitive streak elongation | "any anomaly in the process by which the primitive streak extends anteriorly and elongates towards the distal (cranial) end of the embryo to reach its full length" [MGI:anna] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0012739 | abnormal anterior primitive streak morphology | "any structural anomaly of the anterior region of the vertebrate primitive streak which gives rise to the axial and paraxial mesoderm, the definitive endoderm, the primitive groove, and the primitive node" [MGI:anna] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0020530 | disorganized thalamus | "derangement of the pattern of thalamic tissues" [MGI:smb] |
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Allelic Composition: Zic3tm1Bca/Zic3tm1Bca Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Zic3tm1Bca/Zic3+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0030100 | hemifacial hypoplasia | "unilateral underdevelopment or size reduction of the facial tissues, including muscles and bones; usually due to a reduced number of cells" [HP:0011332, MGI:anna] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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MP:0030285 | mandibular coronoid process hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the thin, flattened, triangular eminence that arises from the upper surface of the mandibular ramus (perpendicular portion)" [MGI:anna] |
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Allelic Composition: Zic3tm1Jwb/Zic3tm1Jwb Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Allelic Composition: Zic3tm1Jwb/Y Genetic Background: either: (involves: 129S6/SvEvTac * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
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