ENSDARG00000058801


Danio rerio

Features
Gene ID: ENSDARG00000058801
  
Biological name :rev3l
  
Synonyms : rev3l / REV3-like, polymerase (DNA directed), zeta, catalytic subunit
  
Possible biological names infered from orthology : DNA polymerase zeta catalytic subunit / O60673 / Q61493 / REV3 like, DNA directed polymerase zeta catalytic subunit
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 3346242
Gene end: 3403033
  
Corresponding Affymetrix probe sets: Dr.2555.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000086696
Ensembl peptide - ENSDARP00000122052
NCBI entrez gene - 569100     See in Manteia.
RefSeq - XM_002665646
RefSeq - XM_021468589
swissprot - F1QSQ9
swissprot - E7FDC5
ZFIN ID - ZDB-GENE-050302-55
Ensembl - ENSDARG00000058801
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 REV3LENSGALG00000015033Gallus gallus
 REV3LENSG00000009413Homo sapiens
 Rev3lENSMUSG00000019841Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nexmifa / neurite extension and migration factor a / NEXMIF* / Q5QGS0* / Q5DTT1* / neurite extension and migration factor*ENSDARG000000892716
nexmifb / neurite extension and migration factor b / NEXMIF* / Q5QGS0* / Q5DTT1* / neurite extension and migration factor*ENSDARG000000292966


Protein motifs (from Interpro)
Interpro ID Name
 IPR006133  DNA-directed DNA polymerase, family B, exonuclease domain
 IPR006134  DNA-directed DNA polymerase, family B, multifunctional domain
 IPR006172  DNA-directed DNA polymerase, family B
 IPR012337  Ribonuclease H-like superfamily
 IPR017964  DNA-directed DNA polymerase, family B, conserved site
 IPR023211  DNA polymerase, palm domain superfamily
 IPR025687  C4-type zinc-finger of DNA polymerase delta
 IPR032757  Domain of unknown function DUF4683


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0019985 translesion synthesis IEA
 biological_processGO:0042276 error-prone translesion synthesis IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0016035 zeta DNA polymerase complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003887 DNA-directed DNA polymerase activity IEA


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Translesion synthesis by POLK
Translesion synthesis by POLI


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000059963 polk / polymerase (DNA directed) kappa / Q9QUG2* / Q9UBT6* / DNA polymerase kappa*  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / complex / reaction
 ENSDARG00000054155 pcna / Q9PTP1 / proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / reaction / complex
 ENSDARG00000029250 poli / polymerase (DNA directed) iota / Q9UNA4* / DNA polymerase iota*  / reaction / complex
 ENSDARG00000042456 MAD2L2 / Q568H3 / zgc:110299 / Q9D752* / Q9UI95* / mitotic arrest deficient 2 like 2* / Mitotic spindle assembly checkpoint protein MAD2B *  / reaction / complex
 ENSDARG00000018296 rev1 / REV1, polymerase (DNA directed) / Q9UBZ9* / Q920Q2* / DNA repair protein REV1 * / REV1, DNA directed polymerase*  / complex / reaction






 

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