ENSDARG00000018296


Danio rerio

Features
Gene ID: ENSDARG00000018296
  
Biological name :rev1
  
Synonyms : rev1 / REV1, polymerase (DNA directed)
  
Possible biological names infered from orthology : DNA repair protein REV1 / Q920Q2 / Q9UBZ9 / REV1, DNA directed polymerase
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 21793565
Gene end: 21816606
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000115859
Ensembl peptide - ENSDARP00000136909
NCBI entrez gene - 570043     See in Manteia.
RefSeq - NM_001123300
RefSeq Peptide - NP_001116772
swissprot - B0UY97
swissprot - A0A0R4ISU0
ZFIN ID - ZDB-GENE-081105-180
Ensembl - ENSDARG00000018296
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 REV1ENSGALG00000016766Gallus gallus
 REV1ENSG00000135945Homo sapiens
 Rev1ENSMUSG00000026082Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
polk / polymerase (DNA directed) kappa / Q9QUG2* / Q9UBT6* / DNA polymerase kappa*ENSDARG0000005996312
poli / polymerase (DNA directed) iota / Q9UNA4* / DNA polymerase iota*ENSDARG0000002925010
polh / polymerase (DNA directed), eta / Q9JJN0* / Q9Y253* / DNA polymerase eta*ENSDARG0000007023110


Protein motifs (from Interpro)
Interpro ID Name
 IPR001126  UmuC domain
 IPR001357  BRCT domain
 IPR012112  DNA repair protein Rev1
 IPR017961  DNA polymerase, Y-family, little finger domain
 IPR025527  Domain of unknown function DUF4414
 IPR031991  DNA repair protein Rev1, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0042276 error-prone translesion synthesis IEA
 biological_processGO:0071897 DNA biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / complex / reaction
 ENSDARG00000042456 MAD2L2 / Q568H3 / zgc:110299 / Q9D752* / Q9UI95* / mitotic arrest deficient 2 like 2* / Mitotic spindle assembly checkpoint protein MAD2B *  / complex / reaction
 ENSDARG00000054155 pcna / Q9PTP1 / proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / complex / reaction
 ENSDARG00000058801 rev3l / REV3-like, polymerase (DNA directed), zeta, catalytic subunit / Q61493* / O60673* / DNA polymerase zeta catalytic subunit * / REV3 like, DNA directed polymerase zeta catalytic subunit*  / complex / reaction
 ENSDARG00000029250 poli / polymerase (DNA directed) iota / Q9UNA4* / DNA polymerase iota*  / reaction / complex
 ENSDARG00000059963 polk / polymerase (DNA directed) kappa / Q9QUG2* / Q9UBT6* / DNA polymerase kappa*  / reaction / complex






 

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