ENSDARG00000070231


Danio rerio

Features
Gene ID: ENSDARG00000070231
  
Biological name :polh
  
Synonyms : polh / polymerase (DNA directed), eta
  
Possible biological names infered from orthology : DNA polymerase eta / Q9JJN0 / Q9Y253
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 813579
Gene end: 824564
  
Corresponding Affymetrix probe sets: Dr.5602.1.A1_at (Zebrafish Array)   NM_001040247_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000115601
NCBI entrez gene - 678520     See in Manteia.
RefSeq - NM_001040247
RefSeq Peptide - NP_001035337
swissprot - F1Q7Z9
ZFIN ID - ZDB-GENE-060421-4949
Ensembl - ENSDARG00000070231
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLHENSGALG00000010317Gallus gallus
 POLHENSG00000170734Homo sapiens
 PolhENSMUSG00000023953Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
poli / polymerase (DNA directed) iota / Q9UNA4* / DNA polymerase iota*ENSDARG0000002925018
rev1 / REV1, polymerase (DNA directed) / Q9UBZ9* / Q920Q2* / DNA repair protein REV1 * / REV1, DNA directed polymerase*ENSDARG0000001829617
polk / polymerase (DNA directed) kappa / Q9QUG2* / Q9UBT6* / DNA polymerase kappa*ENSDARG0000005996316


Protein motifs (from Interpro)
Interpro ID Name
 IPR001126  UmuC domain
 IPR017061  DNA polymerase eta/kappa/iota/IV
 IPR017961  DNA polymerase, Y-family, little finger domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003684 damaged DNA binding IEA


Pathways (from Reactome)
Pathway description
Translesion Synthesis by POLH
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / complex / reaction
 ENSDARG00000054155 pcna / Q9PTP1 / proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / complex / reaction
 ENSDARG00000104709 sprtn / SprT-like N-terminal domain / Q9H040*  / complex / reaction
 ENSDARG00000010051 ufd1l / ubiquitin recognition factor in ER associated degradation 1 / UFD1* / P70362* / Q92890*  / reaction / complex
 ENSDARG00000100487 nploc4 / NPL4 homolog, ubiquitin recognition factor / Q8TAT6*  / reaction / complex
 ENSDARG00000020008 vcp / Q7ZU99 / valosin containing protein / P55072* / Q01853*  / complex / reaction






 

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