ENSGALG00000010317


Gallus gallus

Features
Gene ID: ENSGALG00000010317
  
Biological name :POLH
  
Synonyms : DNA polymerase eta / POLH
  
Possible biological names infered from orthology : Q9JJN0 / Q9Y253
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 30956405
Gene end: 30964870
  
Corresponding Affymetrix probe sets: Gga.7127.1.S1_s_at (Chicken Array)   Gga.7127.2.S1_at (Chicken Array)   GgaAffx.21759.1.S1_at (Chicken Array)   GgaAffx.6516.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000037252
Ensembl peptide - ENSGALP00000050716
NCBI entrez gene - 395102     See in Manteia.
RefSeq - NM_001001304
RefSeq Peptide - NP_001001304
swissprot - F1NCM3
swissprot - Q5ZIW9
Ensembl - ENSGALG00000010317
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polhENSDARG00000070231Danio rerio
 POLHENSG00000170734Homo sapiens
 PolhENSMUSG00000023953Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
REV1 / DNA repair protein REV1 / Q920Q2* / Q9UBZ9* / REV1, DNA directed polymerase*ENSGALG0000001676617
POLK / DNA polymerase kappa / Q9QUG2* / Q9UBT6* / polymerase (DNA directed), kappa*ENSGALG0000001495617


Protein motifs (from Interpro)
Interpro ID Name
 IPR001126  UmuC domain
 IPR017061  DNA polymerase eta/kappa/iota/IV
 IPR017961  DNA polymerase, Y-family, little finger domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000731 DNA synthesis involved in DNA repair IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006290 pyrimidine dimer repair IEA
 biological_processGO:0006301 postreplication repair IEA
 biological_processGO:0010225 response to UV-C IEA
 biological_processGO:0071494 cellular response to UV-C IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003887 DNA-directed DNA polymerase activity IEA


Pathways (from Reactome)
Pathway description
Translesion Synthesis by POLH
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000734 RPA2 / RPA4* / Q13156* / P15927* / replication protein A2* / replication protein A4*  / reaction / complex
 ENSGALG00000003144 TRIM25 / Gallus gallus tripartite motif containing 25 (TRIM25), mRNA. / Q14258* / Q61510* / tripartite motif containing 25* / E3 ubiquitin/ISG15 ligase TRIM25 *  / complex
 ENSGALG00000003072 RPA1 / Q5ZJJ2 / Replication protein A 70 kDa DNA-binding subunit / Q8VEE4* / P27694* / replication protein A1*  / complex / reaction
 ENSGALG00000011065 SPRTN / SprT-like N-terminal domain / G3X912* / Q9H040* / SprT-like domain-containing protein Spartan *  / complex / reaction
 ENSGALG00000010700 RPA3 / replication protein A3 / P35244* / Q9CQ71* / Replication protein A 14 kDa subunit *  / complex / reaction
 ENSGALG00000029292 PCNA / Q9DEA3 / Proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / reaction / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000023335 RCHY1 / ring finger and CHY zinc finger domain containing 1 / Q96PM5* / Q9CR50*  / reaction / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction






 

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