ENSDARG00000042456


Danio rerio

Features
Gene ID: ENSDARG00000042456
  
Biological name :MAD2L2
  
Synonyms : MAD2L2 / Q568H3 / zgc:110299
  
Possible biological names infered from orthology : mitotic arrest deficient 2 like 2 / Mitotic spindle assembly checkpoint protein MAD2B / Q9D752 / Q9UI95
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 22345282
Gene end: 22348391
  
Corresponding Affymetrix probe sets: Dr.17706.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000062253
NCBI entrez gene - 550258     See in Manteia.
RefSeq - XM_005167034
RefSeq Peptide - NP_001017595
swissprot - Q568H3
ZFIN ID - ZDB-GENE-050417-61
Ensembl - ENSDARG00000042456
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAD2L2ENSGALG00000004640Gallus gallus
 MAD2L2ENSG00000116670Homo sapiens
 Mad2l2ENSMUSG00000029003Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003511  HORMA domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation ISS
 biological_processGO:0042177 negative regulation of protein catabolic process ISS
 biological_processGO:0042772 DNA damage response, signal transduction resulting in transcription ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0051301 cell division IEA
 biological_processGO:1904667 negative regulation of ubiquitin protein ligase activity ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005680 anaphase-promoting complex ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle ISS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016035 zeta DNA polymerase complex ISS
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Translesion synthesis by POLK
Translesion synthesis by POLI


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / reaction / complex
 ENSDARG00000059963 polk / polymerase (DNA directed) kappa / Q9QUG2* / Q9UBT6* / DNA polymerase kappa*  / reaction / complex
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / reaction / complex
 ENSDARG00000029250 poli / polymerase (DNA directed) iota / Q9UNA4* / DNA polymerase iota*  / reaction / complex
 ENSDARG00000054155 pcna / Q9PTP1 / proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / reaction / complex
 ENSDARG00000018296 rev1 / REV1, polymerase (DNA directed) / Q9UBZ9* / Q920Q2* / DNA repair protein REV1 * / REV1, DNA directed polymerase*  / complex / reaction
 ENSDARG00000058801 rev3l / REV3-like, polymerase (DNA directed), zeta, catalytic subunit / Q61493* / O60673* / DNA polymerase zeta catalytic subunit * / REV3 like, DNA directed polymerase zeta catalytic subunit*  / complex / reaction






 

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