ENSDARG00000077139


Danio rerio

Features
Gene ID: ENSDARG00000077139
  
Biological name :col6a3
  
Synonyms : col6a3 / collagen, type VI, alpha 3
  
Possible biological names infered from orthology : collagen type VI alpha 3 chain / P12111
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 23914317
Gene end: 23990416
  
Corresponding Affymetrix probe sets: Dr.4077.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000103149
Ensembl peptide - ENSDARP00000118193
Ensembl peptide - ENSDARP00000122619
Ensembl peptide - ENSDARP00000123601
swissprot - F1Q4X1
swissprot - F1QKE8
swissprot - F1QMR9
swissprot - F1QV92
ZFIN ID - ZDB-GENE-070501-8
Ensembl - ENSDARG00000077139
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COL6A3ENSGALG00000003923Gallus gallus
 COL6A3ENSG00000163359Homo sapiens
 Col6a3ENSMUSG00000048126Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
col6a4a / collagen, type VI, alpha 4a / A2AX52* / Col6a4* / Collagen alpha-4(VI) chain *ENSDARG0000007975220
si:ch211-62a1.3 / COL6A5* / COL6A6* / A6NMZ7* / A8TX70* / Q8C6K9* / Collagen alpha-6(VI) chain * / collagen type VI alpha 5 chain* / collagen type VI alpha 6 chain*ENSDARG0000011241915
col12a1b / collagen, type XII, alpha 1b / Q99715* / Q60847* / COL12A1* / Collagen alpha-1(XII) chain * / collagen type XII alpha 1 chain*ENSDARG0000001960111
col12a1a / collagen, type XII, alpha 1a / Q99715* / Q60847* / COL12A1* / Collagen alpha-1(XII) chain * / collagen type XII alpha 1 chain*ENSDARG0000007832211
col7a1 / collagen, type VII, alpha 1 / Q63870* / Q02388* / Collagen alpha-1(VII) chain * / collagen type VII alpha 1 chain*ENSDARG0000002172011
col14a1a / collagen, type XIV, alpha 1a / Q80X19* / Q05707* / COL14A1* / Collagen alpha-1(XIV) chain * / collagen type XIV alpha 1 chain*ENSDARG000000057628
col7a1l / collagen type VII alpha 1-likeENSDARG000000696928
col6a3 / collagen, type VI, alpha 3 / P12111* / collagen type VI alpha 3 chain*ENSDARG000000959158
vwa2 / von Willebrand factor A domain containing 2 / Q5GFL6* / Q70UZ7*ENSDARG000000754414
ch1073-291c23.1 / VIT* / Q6UXI7* / Q8VHI5* / vitrin*ENSDARG000000636314
coch / coagulation factor C homolog, cochlin (Limulus polyphemus) / O43405* / Q62507* / cochlin*ENSDARG000000240323
col14a1b / collagen, type XIV, alpha 1b / Q80X19* / Q05707* / COL14A1* / Collagen alpha-1(XIV) chain * / collagen type XIV alpha 1 chain*ENSDARG000000766233


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR008160  Collagen triple helix repeat
 IPR013783  Immunoglobulin-like fold
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0048675 axon extension IMP
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Collagen biosynthesis and modifying enzymes
Signaling by PDGF
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
ECM proteoglycans
NCAM1 interactions
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001115 trunk trunk increased curvature , abnormal
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 ZFA:0009114 muscle cell muscle cell apoptotic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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