ENSDARG00000078378


Danio rerio

Features
Gene ID: ENSDARG00000078378
  
Biological name :unm_sa808
  
Synonyms : unm_sa808 / un-named sa808
  
Possible biological names infered from orthology : P39429 / Q12933 / TNF receptor associated factor 2 / TRAF2
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 5689476
Gene end: 5696173
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000016657
swissprot - E7F5X7
ZFIN ID - ZDB-GENE-120727-21
Ensembl - ENSDARG00000078378
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRAF2ENSGALG00000042838Gallus gallus
 TRAF2ENSG00000127191Homo sapiens
 Traf2ENSMUSG00000026942Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
traf2a / Tnf receptor-associated factor 2a / TRAF2* / P39429* / Q12933* / TNF receptor associated factor 2*ENSDARG0000003017384
traf2b / Tnf receptor-associated factor 2bENSDARG0000010103667
traf1 / TNF receptor-associated factor 1 / P39428* / Q13077*ENSDARG0000006948243
traf3 / TNF receptor-associated factor 3 / Q13114* / Q60803*ENSDARG0000002200041
traf4a / tnf receptor-associated factor 4a / TRAF4* / Q61382* / Q9BUZ4* / TNF receptor associated factor 4*ENSDARG0000000396326
traf4b / tnf receptor-associated factor 4bENSDARG0000003896425
traf6 / Q6IWL4 / TNF receptor-associated factor 6 / P70196* / Q9Y4K3*ENSDARG0000002805822
traf5 / Tnf receptor-associated factor 5 / O00463*ENSDARG000000172406


Protein motifs (from Interpro)
Interpro ID Name
 IPR002083  MATH/TRAF domain
 IPR008974  TRAF-like
 IPR027133  TNF receptor-associated factor 2
 IPR032070  TNF receptor-associated factor, BIRC3 binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation by c-FLIP
RIPK1-mediated regulated necrosis
CASP8 activity is inhibited
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
TNFR2 non-canonical NF-kB pathway
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Ub-specific processing proteases
Dimerization of procaspase-8
TNF signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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