ENSDARG00000079742


Danio rerio

Features
Gene ID: ENSDARG00000079742
  
Biological name :mcf2l2
  
Synonyms : MCF.2 cell line derived transforming sequence-like 2 / mcf2l2
  
Possible biological names infered from orthology : Q86YR7
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 10467299
Gene end: 10663122
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000134580
Ensembl peptide - ENSDARP00000100489
Ensembl peptide - ENSDARP00000144823
Ensembl peptide - ENSDARP00000149874
swissprot - E7FGN0
swissprot - A0A0R4IGI8
ZFIN ID - ZDB-GENE-100812-1
Ensembl - ENSDARG00000079742
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCF2L2ENSGALG00000008744Gallus gallus
 MCF2L2ENSG00000053524Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mcf2la / mcf.2 cell line derived transforming sequence-like a / MCF2L* / O15068* / MCF.2 cell line derived transforming sequence like*ENSDARG0000007585948
mcf2lb / mcf.2 cell line derived transforming sequence-like b / MCF2L* / O15068* / MCF.2 cell line derived transforming sequence like*ENSDARG0000007648041
mcf2a / MCF.2 cell line derived transforming sequence a / MCF2* / P10911* / MCF.2 cell line derived transforming sequence*ENSDARG0000002289539
mcf2b / MCF.2 cell line derived transforming sequence b / MCF2* / P10911* / MCF.2 cell line derived transforming sequence*ENSDARG0000005660333
trioa / trio Rho guanine nucleotide exchange factor a / TRIO* / Q0KL02* / O75962* / Triple functional domain protein * / trio Rho guanine nucleotide exchange factor*ENSDARG0000001942624
triob / trio Rho guanine nucleotide exchange factor b / TRIO* / O75962* / trio Rho guanine nucleotide exchange factor*ENSDARG0000000037023
kalrna / kalirin RhoGEF kinase a / KALRN* / O60229* / A2CG49* / Kalirin * / kalirin RhoGEF kinase*ENSDARG0000010411922
kalrnb / kalirin RhoGEF kinase b / KALRN* / O60229* / A2CG49* / Kalirin * / kalirin RhoGEF kinase*ENSDARG0000006353810
plekhg2 / pleckstrin homology domain containing, family G (with RhoGef domain) member 2ENSDARG0000005845910
arhgef25b / Rho guanine nucleotide exchange factor (GEF) 25b / Q86VW2* / ARHGEF25* / Rho guanine nucleotide exchange factor 25* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 2...ENSDARG0000001446510
BX539336.1 / Q86VW2* / ARHGEF25* / Rho guanine nucleotide exchange factor 25*ENSDARG000001006069
CABZ01048666.1 / Q9ULL1* / PLEKHG1* / pleckstrin homology and RhoGEF domain containing G1*ENSDARG000001115855
si:ch73-212j7.3 / A1L390* / Q4VAC9* / PLEKHG3* / pleckstrin homology and RhoGEF domain containing G3* / Pleckstrin homology domain-containing family G member 3 *ENSDARG000000966133
FP015810.1 / KALRN* / O60229* / kalirin RhoGEF kinase*ENSDARG000001127492


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018159  Spectrin/alpha-actinin
 IPR035532  DBS, SH3 domain
 IPR035534  DBS, PH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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