ENSDARG00000014465


Danio rerio

Features
Gene ID: ENSDARG00000014465
  
Biological name :arhgef25b
  
Synonyms : arhgef25b / Rho guanine nucleotide exchange factor (GEF) 25b
  
Possible biological names infered from orthology : ARHGEF25 / Mus musculus Rho guanine nucleotide exchange factor (GEF) 25 (Arhgef25), transcript variant 3, mRNA. / Q86VW2 / Rho guanine nucleotide exchange factor 25
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 39256170
Gene end: 39275915
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124934
Ensembl peptide - ENSDARP00000124252
Ensembl peptide - ENSDARP00000152536
NCBI entrez gene - 569561     See in Manteia.
swissprot - E7FF78
swissprot - F8W5Y3
ZFIN ID - ZDB-GENE-080225-17
Ensembl - ENSDARG00000014465
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q86VW2ENSG00000240771Homo sapiens
 Arhgef25ENSMUSG00000019467Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
trioa / trio Rho guanine nucleotide exchange factor a / TRIO* / Q0KL02* / O75962* / Triple functional domain protein * / trio Rho guanine nucleotide exchange factor*ENSDARG0000001942651
triob / trio Rho guanine nucleotide exchange factor b / TRIO* / O75962* / trio Rho guanine nucleotide exchange factor*ENSDARG0000000037050
BX539336.1 / Q86VW2* / ARHGEF25* / Rho guanine nucleotide exchange factor 25*ENSDARG0000010060645
kalrna / kalirin RhoGEF kinase a / KALRN* / O60229* / A2CG49* / Kalirin * / kalirin RhoGEF kinase*ENSDARG0000010411943
kalrnb / kalirin RhoGEF kinase b / KALRN* / O60229* / A2CG49* / Kalirin * / kalirin RhoGEF kinase*ENSDARG0000006353836
mcf2la / mcf.2 cell line derived transforming sequence-like a / MCF2L* / O15068* / MCF.2 cell line derived transforming sequence like*ENSDARG0000007585921
mcf2a / MCF.2 cell line derived transforming sequence a / MCF2* / P10911* / MCF.2 cell line derived transforming sequence*ENSDARG0000002289519
mcf2lb / mcf.2 cell line derived transforming sequence-like b / MCF2L* / O15068* / MCF.2 cell line derived transforming sequence like*ENSDARG0000007648019
mcf2l2 / MCF.2 cell line derived transforming sequence-like 2 / Q86YR7*ENSDARG0000007974219
mcf2b / MCF.2 cell line derived transforming sequence b / MCF2* / P10911* / MCF.2 cell line derived transforming sequence*ENSDARG0000005660316
plekhg2 / pleckstrin homology domain containing, family G (with RhoGef domain) member 2ENSDARG0000005845915
CABZ01048666.1 / Q9ULL1* / PLEKHG1* / pleckstrin homology and RhoGEF domain containing G1*ENSDARG000001115858
si:ch73-212j7.3 / A1L390* / Q4VAC9* / PLEKHG3* / pleckstrin homology and RhoGEF domain containing G3* / Pleckstrin homology domain-containing family G member 3 *ENSDARG000000966137
FP015810.1 / KALRN* / O60229* / kalirin RhoGEF kinase*ENSDARG000001127490


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR030738  Rho guanine nucleotide exchange factor 25


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000011487 gnaq / guanine nucleotide binding protein (G protein), q polypeptide / P50148* / P21279* / G protein subunit alpha q* / guanine nucleotide binding protein, alpha q polypeptide*  / reaction / complex
 ENSDARG00000025013 gna14a / guanine nucleotide binding protein (G protein), alpha 14a / GNA14* / P30677* / O95837* / G protein subunit alpha 14* / guanine nucleotide binding protein, alpha 14*  / complex / reaction
 ENSDARG00000016364 gna15.1 / guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1 / GNA15* / P30679* / P30678* / G protein subunit alpha 15* / guanine nucleotide binding pro...  / reaction / complex






 

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