ENSDARG00000076480


Danio rerio

Features
Gene ID: ENSDARG00000076480
  
Biological name :mcf2lb
  
Synonyms : mcf.2 cell line derived transforming sequence-like b / mcf2lb
  
Possible biological names infered from orthology : MCF.2 cell line derived transforming sequence like / MCF2L / O15068
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 29581662
Gene end: 29616590
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000146540
Ensembl peptide - ENSDARP00000152501
Ensembl peptide - ENSDARP00000099542
Ensembl peptide - ENSDARP00000116427
Ensembl peptide - ENSDARP00000116934
NCBI entrez gene - 569231     See in Manteia.
swissprot - E7F2V3
swissprot - F1R1Z4
swissprot - F1RAS5
ZFIN ID - ZDB-GENE-081104-416
Ensembl - ENSDARG00000076480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCF2LENSGALG00000016834Gallus gallus
 MCF2LENSG00000126217Homo sapiens
 Mcf2lENSMUSG00000031442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mcf2la / mcf.2 cell line derived transforming sequence-like a / MCF2L* / O15068* / MCF.2 cell line derived transforming sequence like*ENSDARG0000007585961
mcf2l2 / MCF.2 cell line derived transforming sequence-like 2 / Q86YR7*ENSDARG0000007974247
mcf2a / MCF.2 cell line derived transforming sequence a / MCF2* / P10911* / MCF.2 cell line derived transforming sequence*ENSDARG0000002289542
mcf2b / MCF.2 cell line derived transforming sequence b / MCF2* / P10911* / MCF.2 cell line derived transforming sequence*ENSDARG0000005660334
trioa / trio Rho guanine nucleotide exchange factor a / TRIO* / Q0KL02* / O75962* / Triple functional domain protein * / trio Rho guanine nucleotide exchange factor*ENSDARG0000001942624
kalrna / kalirin RhoGEF kinase a / KALRN* / O60229* / A2CG49* / Kalirin * / kalirin RhoGEF kinase*ENSDARG0000010411924
triob / trio Rho guanine nucleotide exchange factor b / TRIO* / O75962* / trio Rho guanine nucleotide exchange factor*ENSDARG0000000037023
kalrnb / kalirin RhoGEF kinase b / KALRN* / O60229* / A2CG49* / Kalirin * / kalirin RhoGEF kinase*ENSDARG0000006353811
arhgef25b / Rho guanine nucleotide exchange factor (GEF) 25b / Q86VW2* / ARHGEF25* / Rho guanine nucleotide exchange factor 25* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 2...ENSDARG0000001446511
plekhg2 / pleckstrin homology domain containing, family G (with RhoGef domain) member 2ENSDARG0000005845911
BX539336.1 / Q86VW2* / ARHGEF25* / Rho guanine nucleotide exchange factor 25*ENSDARG000001006069
CABZ01048666.1 / Q9ULL1* / PLEKHG1* / pleckstrin homology and RhoGEF domain containing G1*ENSDARG000001115856
si:ch73-212j7.3 / A1L390* / Q4VAC9* / PLEKHG3* / pleckstrin homology and RhoGEF domain containing G3* / Pleckstrin homology domain-containing family G member 3 *ENSDARG000000966134
FP015810.1 / KALRN* / O60229* / kalirin RhoGEF kinase*ENSDARG000001127490


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018159  Spectrin/alpha-actinin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr