ENSG00000053524


Homo sapiens

Features
Gene ID: ENSG00000053524
  
Biological name :MCF2L2
  
Synonyms : MCF.2 cell line derived transforming sequence-like 2 / MCF2L2 / Q86YR7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q27.1
Gene start: 183178043
Gene end: 183428778
  
Corresponding Affymetrix probe sets: 215112_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328118
Ensembl peptide - ENSP00000417345
Ensembl peptide - ENSP00000491317
Ensembl peptide - ENSP00000420070
Ensembl peptide - ENSP00000388190
Ensembl peptide - ENSP00000414131
NCBI entrez gene - 23101     See in Manteia.
RefSeq - XM_017005946
RefSeq - XM_011512586
RefSeq - XM_017005943
RefSeq - XM_017005944
RefSeq - XM_017005945
RefSeq - NM_015078
RefSeq - XM_011512585
RefSeq Peptide - NP_055893
swissprot - C9J326
swissprot - A0A1W2PP43
swissprot - Q86YR7
Ensembl - ENSG00000053524
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcf2l2ENSDARG00000079742Danio rerio
 MCF2L2ENSGALG00000008744Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCF2L / O15068 / MCF.2 cell line derived transforming sequence likeENSG0000012621741
MCF2 / P10911 / MCF.2 cell line derived transforming sequenceENSG0000010197733
TRIO / O75962 / trio Rho guanine nucleotide exchange factorENSG0000003838224
KALRN / O60229 / kalirin RhoGEF kinaseENSG0000016014514
A1L390 / PLEKHG3 / pleckstrin homology and RhoGEF domain containing G3ENSG0000012682211
Q9ULL1 / PLEKHG1 / pleckstrin homology and RhoGEF domain containing G1ENSG0000012027811
Q9H7P9 / PLEKHG2 / pleckstrin homology and RhoGEF domain containing G2ENSG0000009092410
Q86VW2 / ARHGEF25 / Rho guanine nucleotide exchange factor 25ENSG000002407719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018159  Spectrin/alpha-actinin
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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