ENSG00000126822


Homo sapiens

Features
Gene ID: ENSG00000126822
  
Biological name :PLEKHG3
  
Synonyms : A1L390 / pleckstrin homology and RhoGEF domain containing G3 / PLEKHG3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q23.3
Gene start: 64704102
Gene end: 64750247
  
Corresponding Affymetrix probe sets: 212821_at (Human Genome U133 Plus 2.0 Array)   212823_s_at (Human Genome U133 Plus 2.0 Array)   217044_s_at (Human Genome U133 Plus 2.0 Array)   229952_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450973
Ensembl peptide - ENSP00000451256
Ensembl peptide - ENSP00000489373
Ensembl peptide - ENSP00000247226
Ensembl peptide - ENSP00000378183
Ensembl peptide - ENSP00000450501
Ensembl peptide - ENSP00000450880
Ensembl peptide - ENSP00000450945
NCBI entrez gene - 26030     See in Manteia.
RefSeq - XM_017021158
RefSeq - XM_011536627
RefSeq - XM_011536628
RefSeq - XM_011536629
RefSeq - XM_017021154
RefSeq - XM_017021155
RefSeq - XM_017021156
RefSeq - XM_017021157
RefSeq - NM_001308147
RefSeq - XM_011536624
RefSeq - XM_011536625
RefSeq Peptide - NP_001295076
swissprot - G3V278
swissprot - G3V2V2
swissprot - A1L390
swissprot - G3V3I3
swissprot - A0A0U1RR71
swissprot - G3V311
Ensembl - ENSG00000126822
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-212j7.3ENSDARG00000096613Danio rerio
 ENSGALG00000036199Gallus gallus
 ENSGALG00000037409Gallus gallus
 Q4VAC9ENSMUSG00000052609Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9ULL1 / PLEKHG1 / pleckstrin homology and RhoGEF domain containing G1ENSG0000012027834
Q9H7P9 / PLEKHG2 / pleckstrin homology and RhoGEF domain containing G2ENSG0000009092427
TRIO / O75962 / trio Rho guanine nucleotide exchange factorENSG0000003838216
MCF2L / O15068 / MCF.2 cell line derived transforming sequence likeENSG0000012621713
MCF2 / P10911 / MCF.2 cell line derived transforming sequenceENSG0000010197710
MCF2L2 / Q86YR7 / MCF.2 cell line derived transforming sequence-like 2ENSG0000005352410
Q86VW2 / ARHGEF25 / Rho guanine nucleotide exchange factor 25ENSG0000024077110
KALRN / O60229 / kalirin RhoGEF kinaseENSG000001601451


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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