ENSMUSG00000052609


Mus musculus

Features
Gene ID: ENSMUSG00000052609
  
Biological name :Plekhg3
  
Synonyms : Pleckstrin homology domain-containing family G member 3 / Plekhg3 / Q4VAC9
  
Possible biological names infered from orthology : A1L390 / pleckstrin homology and RhoGEF domain containing G3
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: C3
Gene start: 76530891
Gene end: 76580488
  
Corresponding Affymetrix probe sets: 10396671 (MoGene1.0st)   1434680_at (Mouse Genome 430 2.0 Array)   1440017_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151867
Ensembl peptide - ENSMUSP00000151564
Ensembl peptide - ENSMUSP00000151704
Ensembl peptide - ENSMUSP00000151851
Ensembl peptide - ENSMUSP00000074729
NCBI entrez gene - 263406     See in Manteia.
MGI - MGI:2388284
RefSeq - XM_006515880
RefSeq - XM_006515874
RefSeq - XM_006515875
RefSeq - XM_006515876
RefSeq - XM_006515877
RefSeq - XM_006515878
RefSeq - NM_153804
RefSeq - XM_006515869
RefSeq - XM_006515870
RefSeq - XM_006515871
RefSeq - XM_006515872
RefSeq - XM_006515873
RefSeq Peptide - NP_722499
swissprot - A0A1W2P7Z4
swissprot - A0A1W2P7L9
swissprot - A0A1W2P798
swissprot - Q4VAC9
Ensembl - ENSMUSG00000052609
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-212j7.3ENSDARG00000096613Danio rerio
 ENSGALG00000036199Gallus gallus
 ENSGALG00000037409Gallus gallus
 A1L390ENSG00000126822Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plekhg1 / pleckstrin homology and RhoGEF domain containing G1 / Q9ULL1*ENSMUSG0000004062429
Plekhg2 / pleckstrin homology and RhoGEF domain containing G2 / Q9H7P9*ENSMUSG0000003755224
Trio / Q0KL02 / Triple functional domain protein / O75962* / trio Rho guanine nucleotide exchange factor*ENSMUSG0000002226315
Mcf2l / MCF.2 cell line derived transforming sequence like / O15068*ENSMUSG0000003144211
Arhgef25 / Mus musculus Rho guanine nucleotide exchange factor (GEF) 25 (Arhgef25), transcript variant 3, mRNA. / Q86VW2* / Rho guanine nucleotide exchange factor 25*ENSMUSG000000194679
Mcf2 / MCF.2 cell line derived transforming sequence / P10911*ENSMUSG000000311399
Kalrn / A2CG49 / Kalirin / O60229* / kalirin RhoGEF kinase*ENSMUSG000000617511


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011989  Armadillo-like helical
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011960 abnormal eye anterior chamber depth "anomaly in the distance between the iris and the cornea at the center plane (maximum distance) of the anterior chamber, compared to controls" [MGI:csmith]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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