ENSMUSG00000040624


Mus musculus

Features
Gene ID: ENSMUSG00000040624
  
Biological name :Plekhg1
  
Synonyms : pleckstrin homology and RhoGEF domain containing G1 / Plekhg1
  
Possible biological names infered from orthology : Q9ULL1
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: A1
Gene start: 3740364
Gene end: 3967303
  
Corresponding Affymetrix probe sets: 10367673 (MoGene1.0st)   1435363_at (Mouse Genome 430 2.0 Array)   1440991_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116652
Ensembl peptide - ENSMUSP00000040495
Ensembl peptide - ENSMUSP00000114056
Ensembl peptide - ENSMUSP00000119950
Ensembl peptide - ENSMUSP00000122131
NCBI entrez gene - 213783     See in Manteia.
MGI - MGI:2676551
RefSeq - XM_011243078
RefSeq - NM_001033253
RefSeq - NM_001159942
RefSeq - XM_006512439
RefSeq - XM_006512442
RefSeq - XM_006512443
RefSeq - XM_011243077
RefSeq Peptide - NP_001028425
RefSeq Peptide - NP_001153414
swissprot - F7CES2
swissprot - F7C583
swissprot - Q3UX37
swissprot - F6S200
Ensembl - ENSMUSG00000040624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01048666.1ENSDARG00000111585Danio rerio
 PLEKHG1ENSGALG00000012395Gallus gallus
 Q9ULL1ENSG00000120278Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q4VAC9 / Plekhg3 / Pleckstrin homology domain-containing family G member 3 / A1L390* / pleckstrin homology and RhoGEF domain containing G3*ENSMUSG0000005260928
Plekhg2 / pleckstrin homology and RhoGEF domain containing G2 / Q9H7P9*ENSMUSG0000003755223
Trio / Q0KL02 / Triple functional domain protein / O75962* / trio Rho guanine nucleotide exchange factor*ENSMUSG0000002226316
Mcf2l / MCF.2 cell line derived transforming sequence like / O15068*ENSMUSG0000003144212
Arhgef25 / Mus musculus Rho guanine nucleotide exchange factor (GEF) 25 (Arhgef25), transcript variant 3, mRNA. / Q86VW2* / Rho guanine nucleotide exchange factor 25*ENSMUSG000000194679
Mcf2 / MCF.2 cell line derived transforming sequence / P10911*ENSMUSG000000311399
Kalrn / A2CG49 / Kalirin / O60229* / kalirin RhoGEF kinase*ENSMUSG000000617511


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010087 increased circulating fructosamine level "increase in the concentration in the blood of total non enzymatic glycated proteins in the blood" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pitpnm1tm1a(EUCOMM)Wtsi/Pitpnm1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Pitpnm1tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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