ENSMUSG00000037552


Mus musculus

Features
Gene ID: ENSMUSG00000037552
  
Biological name :Plekhg2
  
Synonyms : pleckstrin homology and RhoGEF domain containing G2 / Plekhg2
  
Possible biological names infered from orthology : Q9H7P9
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A3
Gene start: 28359604
Gene end: 28372599
  
Corresponding Affymetrix probe sets: 10561431 (MoGene1.0st)   1418201_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112881
Ensembl peptide - ENSMUSP00000092228
Ensembl peptide - ENSMUSP00000113449
Ensembl peptide - ENSMUSP00000122050
Ensembl peptide - ENSMUSP00000118217
Ensembl peptide - ENSMUSP00000117062
Ensembl peptide - ENSMUSP00000115651
NCBI entrez gene - 101497     See in Manteia.
MGI - MGI:2141874
RefSeq - XM_011250408
RefSeq - NM_001083912
RefSeq - NM_001290542
RefSeq - NM_138752
RefSeq - XM_006539436
RefSeq - XM_006539437
RefSeq - XM_006539439
RefSeq - XM_006539441
RefSeq - XM_006539442
RefSeq Peptide - NP_001077381
RefSeq Peptide - NP_001277471
RefSeq Peptide - NP_620091
swissprot - D3Z5N8
swissprot - A0A0R4J1S3
swissprot - G5E8T4
swissprot - D3YY99
swissprot - D3Z1B1
swissprot - E9QKB6
swissprot - D6RFC7
Ensembl - ENSMUSG00000037552
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9H7P9ENSG00000090924Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q4VAC9 / Plekhg3 / Pleckstrin homology domain-containing family G member 3 / A1L390* / pleckstrin homology and RhoGEF domain containing G3*ENSMUSG0000005260924
Plekhg1 / pleckstrin homology and RhoGEF domain containing G1 / Q9ULL1*ENSMUSG0000004062424
Trio / Q0KL02 / Triple functional domain protein / O75962* / trio Rho guanine nucleotide exchange factor*ENSMUSG0000002226312
Mcf2l / MCF.2 cell line derived transforming sequence like / O15068*ENSMUSG0000003144210
Mcf2 / MCF.2 cell line derived transforming sequence / P10911*ENSMUSG000000311399
Arhgef25 / Mus musculus Rho guanine nucleotide exchange factor (GEF) 25 (Arhgef25), transcript variant 3, mRNA. / Q86VW2* / Rho guanine nucleotide exchange factor 25*ENSMUSG000000194678
Kalrn / A2CG49 / Kalirin / O60229* / kalirin RhoGEF kinase*ENSMUSG000000617511


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030833 regulation of actin filament polymerization IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr