ENSG00000120278


Homo sapiens

Features
Gene ID: ENSG00000120278
  
Biological name :PLEKHG1
  
Synonyms : pleckstrin homology and RhoGEF domain containing G1 / PLEKHG1 / Q9ULL1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q25.1
Gene start: 150599883
Gene end: 150843665
  
Corresponding Affymetrix probe sets: 226122_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000351318
Ensembl peptide - ENSP00000356295
Ensembl peptide - ENSP00000433107
Ensembl peptide - ENSP00000493494
Ensembl peptide - ENSP00000496254
NCBI entrez gene - 57480     See in Manteia.
RefSeq - XM_017011102
RefSeq - NM_001029884
RefSeq - NM_001329798
RefSeq - NM_001329799
RefSeq - NM_001329800
RefSeq - NM_001329801
RefSeq - XM_005267064
RefSeq - XM_005267065
RefSeq - XM_005267066
RefSeq - XM_006715521
RefSeq - XM_006715522
RefSeq - XM_011535981
RefSeq - XM_011535982
RefSeq - XM_011535983
RefSeq Peptide - NP_001316730
RefSeq Peptide - NP_001025055
RefSeq Peptide - NP_001316727
RefSeq Peptide - NP_001316728
RefSeq Peptide - NP_001316729
swissprot - Q9ULL1
swissprot - Q5JYA6
swissprot - Q5T1F3
swissprot - H0YD71
Ensembl - ENSG00000120278
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01048666.1ENSDARG00000111585Danio rerio
 PLEKHG1ENSGALG00000012395Gallus gallus
 Plekhg1ENSMUSG00000040624Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A1L390 / PLEKHG3 / pleckstrin homology and RhoGEF domain containing G3ENSG0000012682230
Q9H7P9 / PLEKHG2 / pleckstrin homology and RhoGEF domain containing G2ENSG0000009092424
TRIO / O75962 / trio Rho guanine nucleotide exchange factorENSG0000003838215
MCF2L / O15068 / MCF.2 cell line derived transforming sequence likeENSG0000012621712
MCF2 / P10911 / MCF.2 cell line derived transforming sequenceENSG000001019779
MCF2L2 / Q86YR7 / MCF.2 cell line derived transforming sequence-like 2ENSG000000535248
Q86VW2 / ARHGEF25 / Rho guanine nucleotide exchange factor 25ENSG000002407718
KALRN / O60229 / kalirin RhoGEF kinaseENSG000001601451


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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