ENSDARG00000079766


Danio rerio

Features
Gene ID: ENSDARG00000079766
  
Biological name :tap1
  
Synonyms : tap1 / transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
  
Possible biological names infered from orthology : P21958 / Q03518 / transporter 1, ATP binding cassette subfamily B member
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 48678655
Gene end: 48708045
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124923
Ensembl peptide - ENSDARP00000148638
NCBI entrez gene - 100333043     See in Manteia.
RefSeq - XM_002665007
swissprot - E7F8A9
ZFIN ID - ZDB-GENE-050517-43
Ensembl - ENSDARG00000079766
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TAP1ENSGALG00000035075Gallus gallus
 TAP1ENSG00000168394Homo sapiens
 Tap1ENSMUSG00000037321Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abcb9 / ATP-binding cassette, sub-family B (MDR/TAP), member 9 / Q9JJ59* / Q9NP78* / ATP binding cassette subfamily B member 9*ENSDARG0000005620039
tap2a / transporter associated with antigen processing, subunit type a / TAP2* / Q03519* / P36371* / AL669918.1* / transporter 2, ATP binding cassette subfamily B member* / transporter 2, A...ENSDARG0000003678737
tap2t / transporter associated with antigen processing, subunit type t, teleost specific / TAP2* / Q03519* / P36371* / AL669918.1* / transporter 2, ATP binding cassette subfamily B member* ...ENSDARG0000003344633
abcb10 / ATP-binding cassette, sub-family B (MDR/TAP), member 10 / Q9JI39* / Q9NRK6* / ATP binding cassette subfamily B member 10*ENSDARG0000006159130
abcb8 / ATP-binding cassette, sub-family B (MDR/TAP), member 8 / Q9CXJ4* / Q9NUT2* / ATP binding cassette subfamily B member 8*ENSDARG0000005667228


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR013306  Antigen peptide transporter 1
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015833 peptide transport IEA
 biological_processGO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IEA
 biological_processGO:0042886 amide transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0042825 TAP complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015440 peptide-transporting ATPase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042287 MHC protein binding IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA
 molecular_functionGO:0046979 TAP2 binding IEA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000033446 tap2t / transporter associated with antigen processing, subunit type t, teleost specific / TAP2* / Q03519* / P36371* / AL669918.1* / transporter 2, ATP binding cassette subfamily B member* ...  / complex
 ENSDARG00000045011 tapbp.2 / TAP binding protein (tapasin), tandem duplicate 2 / TAPBP* / O15533* / TAP binding protein*  / reaction
 ENSDARG00000079402 tapbp.1 / TAP binding protein (tapasin), tandem duplicate 1 / TAPBP* / O15533* / TAP binding protein*  / reaction
 ENSDARG00000076290 calr / calreticulin / P14211* / P27797*  / reaction
 ENSDARG00000100435 Q7SXP0 / sec22bb / SEC22 homolog B, vesicle trafficking protein b / SEC22B* / O08547* / O75396* / Vesicle-trafficking protein SEC22b * / SEC22 homolog B, vesicle trafficking protein (gene/p...  / reaction






 

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