ENSDARG00000088293


Danio rerio

Features
Gene ID: ENSDARG00000088293
  
Biological name :doc2b
  
Synonyms : doc2b / double C2-like domains, beta
  
Possible biological names infered from orthology : double C2 domain beta / Double C2-like domain-containing protein beta / P70169
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 60919378
Gene end: 61329656
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000156231
Ensembl peptide - ENSDARP00000108848
Ensembl peptide - ENSDARP00000111593
NCBI entrez gene - 100006713     See in Manteia.
swissprot - F1QDX5
swissprot - F1QTK2
ZFIN ID - ZDB-GENE-090615-1
Ensembl - ENSDARG00000088293
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000004917Gallus gallus
 DOC2BENSG00000272636Homo sapiens
 Doc2bENSMUSG00000020848Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rph3ab / rabphilin 3A homolog (mouse), b / RPH3A* / Q9Y2J0* / rabphilin 3A*ENSDARG0000010549040
si:dkey-93n13.3 / DOC2A* / Q14183* / Q7TNF0* / double C2 domain alpha* / Double C2-like domain-containing protein alpha *ENSDARG0000007873634
doc2d / double C2-like domains, delta / Doc2g*ENSDARG0000007996233
sytl4 / synaptotagmin-like 4 / Q96C24* / Q9R0Q1*ENSDARG0000010243318
sytl2b / synaptotagmin-like 2b / SYTL2* / Q9HCH5* / Q99N50* / synaptotagmin like 2* / Synaptotagmin-like protein 2 *ENSDARG0000007543617
sytl5 / synaptotagmin-like 5 / Q80T23* / Q8TDW5*ENSDARG0000006213517
si:ch211-266g18.6ENSDARG0000000338116
sytl1 / synaptotagmin-like 1 / Q8IYJ3*ENSDARG0000007009415
sytl2a / synaptotagmin-like 2a / SYTL2* / Q9HCH5* / synaptotagmin like 2*ENSDARG0000006195613
sytl3 / synaptotagmin-like 3 / Q4VX76* / Q99N48* / Synaptotagmin-like protein 3 *ENSDARG0000004346813
rph3aa / rabphilin 3A homolog (mouse), a / RPH3A* / Q9Y2J0* / rabphilin 3A*ENSDARG0000006343613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR010911  Rab-binding domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR030534  Double C2-like domain-containing protein beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0031340 positive regulation of vesicle fusion IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070382 exocytic vesicle IBA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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