ENSG00000272636


Homo sapiens

Features
Gene ID: ENSG00000272636
  
Biological name :DOC2B
  
Synonyms : DOC2B / double C2 domain beta
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.3
Gene start: 142789
Gene end: 181636
  
Corresponding Affymetrix probe sets: 207311_at (Human Genome U133 Plus 2.0 Array)   236045_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482950
NCBI entrez gene - 8447     See in Manteia.
OMIM - 604568
RefSeq - NM_003585
RefSeq - XM_011535363
RefSeq Peptide - NP_003576
swissprot - A0A087WZX8
Ensembl - ENSG00000272636
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 doc2bENSDARG00000088293Danio rerio
 ENSGALG00000004917Gallus gallus
 Doc2bENSMUSG00000020848Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RPH3A / Q9Y2J0 / rabphilin 3AENSG0000008916963
DOC2A / Q14183 / double C2 domain alphaENSG0000014992761
SYTL4 / Q96C24 / synaptotagmin like 4ENSG0000010236228
SYTL5 / Q8TDW5 / synaptotagmin like 5ENSG0000014704126
SYTL2 / Q9HCH5 / synaptotagmin like 2ENSG0000013750125
SYTL1 / Q8IYJ3 / synaptotagmin like 1ENSG0000014276522
SYTL3 / Q4VX76 / synaptotagmin like 3ENSG0000016467420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR014638  Double C2 protein, alpha/beta/gamma
 IPR030534  Double C2-like domain-containing protein beta
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031340 positive regulation of vesicle fusion IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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