ENSG00000137501


Homo sapiens

Features
Gene ID: ENSG00000137501
  
Biological name :SYTL2
  
Synonyms : Q9HCH5 / synaptotagmin like 2 / SYTL2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q14.1
Gene start: 85694224
Gene end: 85811159
  
Corresponding Affymetrix probe sets: 220613_s_at (Human Genome U133 Plus 2.0 Array)   225496_s_at (Human Genome U133 Plus 2.0 Array)   232914_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432996
Ensembl peptide - ENSP00000432144
Ensembl peptide - ENSP00000434010
Ensembl peptide - ENSP00000489554
Ensembl peptide - ENSP00000489269
Ensembl peptide - ENSP00000489095
Ensembl peptide - ENSP00000488994
Ensembl peptide - ENSP00000437005
Ensembl peptide - ENSP00000436678
Ensembl peptide - ENSP00000436164
Ensembl peptide - ENSP00000435855
Ensembl peptide - ENSP00000435238
Ensembl peptide - ENSP00000434621
Ensembl peptide - ENSP00000434111
Ensembl peptide - ENSP00000318803
Ensembl peptide - ENSP00000352065
Ensembl peptide - ENSP00000374608
Ensembl peptide - ENSP00000374610
Ensembl peptide - ENSP00000431701
Ensembl peptide - ENSP00000431703
Ensembl peptide - ENSP00000432116
Ensembl peptide - ENSP00000432137
NCBI entrez gene - 54843     See in Manteia.
OMIM - 612880
RefSeq - XM_017017940
RefSeq - XM_005274060
RefSeq - XM_005274061
RefSeq - XM_005274062
RefSeq - XM_005274063
RefSeq - XM_005274066
RefSeq - XM_005274067
RefSeq - XM_011545105
RefSeq - XM_011545106
RefSeq - XM_011545107
RefSeq - XM_011545108
RefSeq - XM_011545109
RefSeq - XM_011545110
RefSeq - XM_011545114
RefSeq - XM_011545115
RefSeq - XM_011545116
RefSeq - XM_017017933
RefSeq - XM_017017934
RefSeq - XM_017017935
RefSeq - XM_017017936
RefSeq - XM_017017937
RefSeq - XM_017017938
RefSeq - XM_017017939
RefSeq - NM_001162951
RefSeq - NM_001162952
RefSeq - NM_001162953
RefSeq - NM_001289608
RefSeq - NM_001289609
RefSeq - NM_001289610
RefSeq - NM_032943
RefSeq - NM_206929
RefSeq - NM_206930
RefSeq - XM_005274057
RefSeq Peptide - NP_001156424
RefSeq Peptide - NP_001156425
RefSeq Peptide - NP_001276537
RefSeq Peptide - NP_001276538
RefSeq Peptide - NP_001276539
RefSeq Peptide - NP_116561
RefSeq Peptide - NP_996812
RefSeq Peptide - NP_996813
RefSeq Peptide - NP_001156423
swissprot - A0A0U1RR07
swissprot - A0A0U1RQP0
swissprot - E9PS39
swissprot - Q9HCH5
swissprot - A0A0U1RQH1
swissprot - E9PS29
swissprot - E9PRW5
swissprot - E9PQL8
swissprot - E9PPL3
swissprot - E9PK22
swissprot - E9PIB5
swissprot - A0A1Y8EH08
swissprot - A0A0U1RRJ3
Ensembl - ENSG00000137501
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sytl2aENSDARG00000061956Danio rerio
 sytl2bENSDARG00000075436Danio rerio
 ENSGALG00000008326Gallus gallus
 Sytl2ENSMUSG00000030616Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYTL1 / Q8IYJ3 / synaptotagmin like 1ENSG0000014276525
SYTL4 / Q96C24 / synaptotagmin like 4ENSG0000010236223
SYTL5 / Q8TDW5 / synaptotagmin like 5ENSG0000014704123
SYTL3 / Q4VX76 / synaptotagmin like 3ENSG0000016467418
RPH3A / Q9Y2J0 / rabphilin 3AENSG0000008916914
DOC2B / double C2 domain betaENSG0000027263611
DOC2A / Q14183 / double C2 domain alphaENSG0000014992710


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR010911  Rab-binding domain
 IPR027006  Synaptotagmin-like protein 2
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006887 exocytosis IDA
 biological_processGO:0006904 vesicle docking involved in exocytosis IDA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0010923 negative regulation of phosphatase activity IDA
 biological_processGO:0016192 vesicle-mediated transport ISS
 biological_processGO:0070257 positive regulation of mucus secretion IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0019897 extrinsic component of plasma membrane ISS
 cellular_componentGO:0042470 melanosome ISS
 cellular_componentGO:0070382 exocytic vesicle IDA
 molecular_functionGO:0001786 phosphatidylserine binding IMP
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IMP
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0019902 phosphatase binding IDA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0042043 neurexin family protein binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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