ENSG00000089169


Homo sapiens

Features
Gene ID: ENSG00000089169
  
Biological name :RPH3A
  
Synonyms : Q9Y2J0 / rabphilin 3A / RPH3A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.13
Gene start: 112570380
Gene end: 112898881
  
Corresponding Affymetrix probe sets: 205230_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450382
Ensembl peptide - ENSP00000450216
Ensembl peptide - ENSP00000450347
Ensembl peptide - ENSP00000374036
Ensembl peptide - ENSP00000405357
Ensembl peptide - ENSP00000440384
Ensembl peptide - ENSP00000446556
Ensembl peptide - ENSP00000446570
Ensembl peptide - ENSP00000446780
Ensembl peptide - ENSP00000446789
Ensembl peptide - ENSP00000447083
Ensembl peptide - ENSP00000447306
Ensembl peptide - ENSP00000447505
Ensembl peptide - ENSP00000447639
Ensembl peptide - ENSP00000448100
Ensembl peptide - ENSP00000448297
Ensembl peptide - ENSP00000448662
Ensembl peptide - ENSP00000449613
Ensembl peptide - ENSP00000449650
Ensembl peptide - ENSP00000449705
NCBI entrez gene - 22895     See in Manteia.
OMIM - 612159
RefSeq - NM_001347952
RefSeq - NM_001143854
RefSeq - NM_001347953
RefSeq - NM_001347954
RefSeq - NM_001347955
RefSeq - NM_014954
RefSeq - XM_011538048
RefSeq Peptide - NP_001334883
RefSeq Peptide - NP_001334884
RefSeq Peptide - NP_055769
RefSeq Peptide - NP_001334882
RefSeq Peptide - NP_001137326
RefSeq Peptide - NP_001334881
swissprot - F8W1A3
swissprot - F8W1K7
swissprot - F8VNP7
swissprot - Q9Y2J0
swissprot - F8VNU2
swissprot - F8VNW3
swissprot - F8VP47
swissprot - F8VR41
swissprot - F8VRJ1
swissprot - F8VV58
swissprot - F8VTR7
swissprot - F8VVK8
swissprot - F8VZS2
swissprot - F8W045
swissprot - F8W116
swissprot - F8W131
Ensembl - ENSG00000089169
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rph3aaENSDARG00000063436Danio rerio
 rph3abENSDARG00000105490Danio rerio
 RPH3AENSGALG00000004840Gallus gallus
 Rph3aENSMUSG00000029608Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DOC2B / double C2 domain betaENSG0000027263637
DOC2A / Q14183 / double C2 domain alphaENSG0000014992733
SYTL4 / Q96C24 / synaptotagmin like 4ENSG0000010236222
SYTL5 / Q8TDW5 / synaptotagmin like 5ENSG0000014704121
SYTL2 / Q9HCH5 / synaptotagmin like 2ENSG0000013750118
SYTL1 / Q8IYJ3 / synaptotagmin like 1ENSG0000014276517
SYTL3 / Q4VX76 / synaptotagmin like 3ENSG0000016467416


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR010911  Rab-binding domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR028698  Rabphilin-3A
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005794 Golgi apparatus ISS
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008021 synaptic vesicle TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030141 secretory granule ISS
 cellular_componentGO:0030672 synaptic vesicle membrane ISS
 cellular_componentGO:0032991 protein-containing complex ISS
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0045202 synapse ISS
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0008430 selenium binding ISS
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0042301 phosphate ion binding ISS
 molecular_functionGO:0044877 protein-containing complex binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070679 inositol 1,4,5 trisphosphate binding ISS
 molecular_functionGO:1901981 phosphatidylinositol phosphate binding TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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